Clinical trials: Mask
Gastric Insufflation
Gastric Insufflation During Positive Pressure Ventilation
Effect of peak inspiratory pressure on the gastric insufflation is evaluated using ultrasonography during face mask ventilation in obese adults.
- Trial name
- NCT04964882
- Testing
- ultrasound examination of air insufflation in the upper esophageal region and stomach
- Volunteers
- 78 people
- Sponsor
- SMG-SNU Boramae Medical Center
Airway Management, Intubation, Intratracheal
The Difficult Airway Management Trial: "The DIFFICAIR-Trial"
In general anesthetic the patient is deprived of his awareness and ability to breathe. It is therefore one of the most important tasks in anesthesia to ensure the patient's airway and breathing.
- Trial name
- DIFFICAIR (NCT01718561)
- Testing
- SARI
- Where
- 28 sites in Denmark
- Volunteers
- 76,058 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Child Development, Cognitive Development
Efficacy of Micronutrient Fortified Yoghurt in School Children for Health Benefits
To evaluate the efficacy of consumption of yoghurt fortified with 30% recommended dietary allowance (RDA) of essential micronutrients (iron, zinc, vitamin A and iodine) for a period of one year in comparison to same yoghurt…
- Conditions
- Child Development, Cognitive Development, Morbidity, Physical Growth
- Trial name
- NCT00980733
- Testing
- Fortified Yoghurt, Yoghurt
- Where
- Bangladesh
- Volunteers
- 1,325 people
- Sponsor
- Annamalai University
Glaucoma
Study to Evaluate Safety and Efficacy of rhNGF Eye Drops Solution Versus Vehicle in Patients With Glaucoma
The primary objective of the study is to assess the safety and tolerability of a 180μg/ml TID dose regimen of recombinant human nerve growth factor (rhNGF) eye drop solution administered over 8 weeks versus a vehicle control in…
- Trial name
- NGF-Glaucoma (NCT02855450)
- Testing
- rhNGF, Vehicle
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Dompé Farmaceutici S.p.A
Glaucoma, Ocular Hypertension
Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension
This purpose of this study is to access the efficacy, tolerability and safety of RKI983 (0.05% and 0.10%) ophthalmic solution bid versus once daily latanoprost 0.005%, in patients with POAG or ocular hypertension.
- Trial name
- NCT00846989
- Testing
- RKI983A, Latanoprost
- Where
- 29 sites in United States
- Volunteers
- 276 people
- Sponsor
- Novartis Pharmaceuticals
Endothelial Cell Density Loss
Study of Endothelial Cell Condition After Cataract Surgery Performed Using Capsulorhexis or ZEPTO
This study will use images of the subjects' corneal endothelium obtained using non-invasive specular microscopy to obtain corneal endothelial cell density, the coefficient of variation in endothelial cell size, and the percentage…
- Trial name
- ZEPTO (NCT04882189)
- Testing
- Imaging
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centricity Vision, Inc.
Age Related Macular Degeneration
Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)
The study will test if the efficacy and safety of an alternative dosing regimen is as effective as monthly injections.
- Trial name
- EXCITE (NCT00275821)
- Testing
- Ranibizumab 0.3 mg - 3 times monthly, then quarterly, Ranibizumab 0.5 mg - 3 times monthly, then quarterly, Ranibizumab 0.3 mg monthly
- Where
- Switzerland
- Volunteers
- 353 people
- Sponsor
- Novartis
Primary Open-Angle Glaucoma, Ocular Hypertension
Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension
The objective of this Phase 2 study is to evaluate whether the Bimatoprost Ocular Insert is non-inferior to that of timolol ophthalmic solution (0.5%) at 12 weeks.
- Trial name
- NCT01915940
- Testing
- Bimatoprost, Timolol 0.5%
- Where
- 10 sites in United States
- Volunteers
- 169 people
- Sponsor
- ForSight Vision5, Inc.
Respiratory Failure, Bronchiolitis
Using HFNC in Bronchiolitis
The investigators compared oxygen therapy using the HFNC and diffuser mask (an effective low-flow oxygen delivery system) to treat patients with moderate-to-severe acute bronchiolitis admitted to an intensive care unit (ICU).
- Trial name
- NCT03342781
- Testing
- high flow nasal oxygen therapy, Diffuser oxygen mask
- Volunteers
- 60 people
- Sponsor
- Kayseri Training and Research Hospital
Intermediate Age-Related Macular Degeneration
QA108 Phase II Study in Subjects With Intermediate Age-Related Macular Degeneration
This is a phase 2, randomized, double-masked, placebo-controlled, multicenter study. To evaluate the efficacy and safety of QA108 granules in the treatment of intermediate age-related macular degeneration.
- Trial name
- NCT05562219
- Testing
- QA108 granules
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Smilebiotek Zhuhai Limited
Pediatric Anesthesia, Airway Management
Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children
This study uses a prospective, up-and-down sequential allocation method to determine the median effective dose (ED50) and 95% effective dose (ED95) of alfentanil combined with propofol for successful laryngeal mask airway (LMA)…
- Conditions
- Pediatric Anesthesia, Airway Management, General Anesthesia, LMA
- Trial name
- NCT07581665
- Testing
- Alfentanil
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Sevoflurane
Sevoflurane-remifentanil EC50 (The 50% Effective Concentration) Values for LMA-Supreme Versus LMA ProSeal Insertion
The study was designed to determine and compare the sevoflurane EC50 optimal concentration for laryngeal mask airway Supreme versus laryngeal mask airway ProSeal insertion during target-controlled infusion of remifentanil.
- Trial name
- NCT03003377
- Testing
- laryngeal mask supreme, laryngeal mask proseal
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Morbid Obesity, Airway Complication of Anesthesia
Evaluation of SaCo Videolaryngeal Mask Airway in Morbidly Obese
SaCo videolaryngeal mask airway is a novel third generation supraglottic device allowing for continuous observation of entrance to larynx via inserted in special channel videoscope connected with cable with external monitor.
- Conditions
- Morbid Obesity, Airway Complication of Anesthesia, Intubation Complication, Intubation; Difficult or Failed
- Trial name
- NCT05680909
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz
Hypoxia
Double Trunk Mask and Standard Nasal Cannula During Acute Hypoxia
The objective of the study is to determine whether adjunctive mask of our design (Double Trunk Mask - DTM) has an effect on increasing arterial pressure in Oxygen (PaO2) diagnosed with severe hypoxia.
- Trial name
- NCT03457363
- Testing
- DTM will be add above NC
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Laboratory of Movement, Condorcet, Tournai, Belgium
Cardiac Arrest During and/or Resulting From A Procedure
Prehospital Laryngeal Tube vs. Bag-Valve Mask Ventilation Used by Paramedics During CPR
During CPR bag-valve mask ventilation is difficult for basically skilled rescuers. Ventilation may be inefficient or with too high pressures result in stomach inflation and aspiration.
- Trial name
- NCT01718795
- Testing
- Bag-valve mask or laryngeal tube ventilation
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Michael Baubin, MD
Diabetic Macular Edema
A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME)
This is a randomized, masked, active-controlled, parallel-group, multi-center study that will assess the efficacy of ILUVIEN as a baseline therapy in the treatment of Center Involving DME (CI-DME).
- Trial name
- NEW DAY (NCT04469595)
- Testing
- Iluvien 0.19 MG Drug Implant, Aflibercept
- Where
- 40 sites in United States
- Volunteers
- 300 people
- Sponsor
- Alimera Sciences
Anesthesia
Effects of One-handed and Two-handed Mask Ventilation Techniques on Global and Regional Lung Ventilation
Two-handed mask ventilation has been shown to provide higher tidal volume than one-handed mask ventilation. The effects of the two techniques on respiratory mechanics during induction of general anesthesia, however, still need to…
- Trial name
- NCT04617665
- Testing
- One-handed mask ventilation, Two-handed mask ventilation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fudan University
Neonatal Resuscitation, Neonatal Disease
Pedi-Cap CO2 Detector for Face-mask Ventilation in the Delivery Room
The goal of this study is to determine if using a Pedi-Cap (a type of colorimetric carbon dioxide detector) during face mask ventilation (PPV) for newborn infants in the delivery room will lower the time of PPV needed.
- Trial name
- CO2-Vent (NCT06258187)
- Testing
- Pedi-Cap
- Where
- United States
- Volunteers
- 632 people
- Sponsor
- University of Texas Southwestern Medical Center
Inflammatory Reaction Due to Ocular Lens Prosthesis
Efficacy and Safety Study of IBI-10090 in Patients Undergoing Cataract Surgery
This study will test the efficacy and safety of IBI-10090 for the reduction of ocular inflammation after cataract surgery.
- Trial name
- NCT01048593
- Testing
- IBI-10090
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- ICON Bioscience Inc
Allergic Conjunctivitis
Study Evaluating the Efficacy and Safety of PRT-2761 for the Treatment of Acute and Chronic Allergic Conjunctivitis
To evaluate the efficacy and safety of two concentrations of PRT-2761 as a topical ophthalmic solution for the treatment of the signs and symptoms of acute and chronic allergic conjunctivitis.
- Trial name
- NCT03320434
- Testing
- PRT-2761 0.5%, PRT-2761 1%, Patanol
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- ORA, Inc.
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