Clinical trials: Mask
Intraocular Lens Replacement, Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome Undergoing Intraocular Lens Replacement Surgery
The purpose of this study is to evaluate the effect of OMS302 on the signs of Intraoperative Floppy Iris Syndrome in patients at risk.
- Trial name
- NCT02093689
- Testing
- Part 1 OMS302, Part 2 OMS302
- Where
- 2 sites in Austria, Germany
- Volunteers
- 18 people
- Sponsor
- Omeros Corporation
Ocular Hypertension, Open Angle Glaucoma
A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdom
Study PhXA41 for its non-inferiority compared with timolol in lowering intra-ocular pressure
- Trial name
- NCT00751049
- Testing
- timolol, PhXA41
- Where
- 12 sites in United Kingdom
- Volunteers
- 294 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Self Cleaning
Evaluation of the Effectiveness of Fibrous Foods, Sugar-free Gomes and Rolly Brush® in the Dental Biofilm Removal
The objective of this study was to evaluate the efficacy of three methods for removal of dental biofilm when compared to dental toothbrushing control.
- Trial name
- NCT03601585
- Testing
- Comparison of dental biofilm removal.
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Hyperemia
Safety of Brimonidine Tartrate Ophthalmic Solution in a Population of Pediatric, Adult, and Geriatric Participants
To compare the safety and tolerability of brimonidine tartrate ophthalmic solution 0.025% versus its vehicle in a population of pediatric, adult, and geriatric participants.
- Trial name
- NCT01959243
- Testing
- Brimonidine Tartrate, Vehicle, Sodium Fluorescein
- Where
- 4 sites in United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Pulmonary Function
Comparative Study Between CPAP Mask and Stacked Breathing o Pneumonia
the study aimed to compare the effect of using NIV with using CPAP mask and stacked breathing exercise and its efficacy on chest expansion and pulmonary functions in pneumonic patients.
- Trial name
- CPAP (NCT04576221)
- Testing
- stacked breathing exercise, NIV by CPAP mask
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ahmed talaat ahmed aly
Head and Neck Tumors
Effectiveness of autoHYpnosis in the Prevention of Anxiety During Radiotherapy of Head and Neck Tumors (HYMACO)
HYMACO is a monocentric, randomized comparative pilot study with a total duration of 25 months. The purpose of this study is to evaluate the effectiveness of autoHYpnosis by anchoring in the prevention of anxiety related to…
- Trial name
- HYMACO (NCT04671485)
- Testing
- Standard care, Autohypnosis, Musicotherapy
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Institut de Cancérologie de Lorraine
Laryngeal Mask Airway
Laryngeal Mask Airway (LMA) Complication in Children
Desflurane is known to be the most pungent of the currently used volatile anesthetics. The investigators tried to find out if desflurane increases the incidence of perioperative upper airway complications in infants and children…
- Trial name
- NCT02644226
- Testing
- Sevoflurane, Desflurane
- Volunteers
- 3,528 people
- Sponsor
- Seoul National University Bundang Hospital
Baska Mask
A Comparative Study of the Baska Mask Vs Proseal Laryngeal Mask Regarding Airway Sealing Pressure
Baska mask air way(BM) in comparative study with Proseal laryngeal mask airway (PLMA) regarding performance of Baska mask improves the safety and efficacy of airway management for in patients undergoing general anesthesia by…
- Trial name
- NCT03812081
- Testing
- Group A : Baska Mask Airway, Group B: Proseal Laryngeal Mask Airway
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cairo University
Second Degree Perineal Tear During Delivery - Delivered, Episiotomy; Complications
Perineal Local Infiltration Study
The prevalence of birth canal lacerations is more than 70% of all deliveries in Canada. The repair of such lacerations is usually done using a pre-existing epidural analgesia.
- Conditions
- Second Degree Perineal Tear During Delivery - Delivered, Episiotomy; Complications, Anesthesia, Local
- Trial name
- PLIS (NCT03672500)
- Testing
- Bupivacaine 0.5%+Epinephrine 50mc
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Age-Related Maculopathy, Age-Related Maculopathies
Safety And Tolerability Study Of RN6G In Patients With Dry, Age-Related Macular Degeneration
The purpose of this study is to determine the safety and tolerability of RN6G in patients with dry, age-related macular degeneration.
- Conditions
- Age-Related Maculopathy, Age-Related Maculopathies, Eye Diseases, Retinal Degeneration
- Trial name
- NCT00877032
- Testing
- RN6G
- Where
- 20 sites in United States
- Volunteers
- 57 people
- Sponsor
- Pfizer
Paediatric Airway
Ultrasound Evaluation of Laryngeal Mask Airway (LMA) Placement in Pediatric Patients and Its Relationship to Postoperative Complications
This study was designed to improve understanding of some respiratory reactions that can occur after surgery, such as difficulty breathing or persistent cough.
- Trial name
- LMAUSPED (NCT06712732)
- Volunteers
- 340 people
- Sponsor
- University Of Perugia
Diabetes Mellitus, Macular Edema
A Study of Ranibizumab Injection in Subjects With Clinically Significant Macular Edema (ME) With Center Involvement Secondary to Diabetes Mellitus (RISE)
This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study of the efficacy and safety of ranibizumab injection in patients with clinically significant macular edema with center involvement…
- Trial name
- RISE (NCT00473330)
- Testing
- Ranibizumab
- Volunteers
- 377 people
- Sponsor
- Genentech, Inc.
Exudative Macular Degeneration, Retinal Hemorrhage
Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular AMD
This study will recruit patients who have recently had a submacular haemorrhage (bleed under the part of the retina responsible for detailed vision), as a complication of wet age-related macular degeneration (wet AMD).
- Trial name
- TAPAS (NCT01835067)
- Testing
- Ranibizumab, C3F8 Gas, tPA
- Where
- 5 sites in United Kingdom
- Volunteers
- 55 people
- Sponsor
- King's College Hospital NHS Trust
Macular Edema, Retinal Vein Occlusion
A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO)
This Phase 3 study will evaluate the efficacy, durability, and safety of KSI-301 compared to aflibercept, in participants with macular edema due to treatment-naïve branch (BRVO) or central retinal vein occlusion (CRVO).
- Trial name
- BEACON (NCT04592419)
- Testing
- KSI-301, Aflibercept
- Where
- 141 sites in United States, Czechia and 10 more
- Volunteers
- 568 people
- Sponsor
- Kodiak Sciences Inc
Healthy Subjects
A Study to Explore the Physiological Impact of AIR+ KN95 Masks on Children
The primary objective is to evaluate the physiological impact of AIR+ KN95 Masks on end-tidal carbon dioxide (ETCO2) of children aged 7 to 14 years of age.
- Trial name
- NCT07037381
- Testing
- KN95 mask
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Innosparks Pte Ltd.
Unilateral Cataract Extraction, Congenital Cataract
A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement
The purpose of this study is to evaluate the effect of OMS302 compared to phenylephrine when administered in irrigation solution during cataract extraction on intraoperative pupil diameter, acute postoperative pain, and safety in…
- Trial name
- ILR7 (NCT02132312)
- Testing
- OMS302, Phenylephrine HCl
- Where
- 11 sites in United States
- Volunteers
- 78 people
- Sponsor
- Omeros Corporation
Idiopathic Gastroparesis
Nortriptyline for Idiopathic Gastroparesis
The principal objective of this multicenter, randomized, placebo-controlled trial is to evaluate whether treatment with nortriptyline will improve gastroparesis symptoms compared with placebo.
- Trial name
- NORIG (NCT00765895)
- Testing
- Nortriptyline Hydrochloride
- Where
- 7 sites in United States
- Volunteers
- 130 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Myopia
Evaluation of Short Term Use of Experimental Eye Drops BHVI2, 0.02% Atropine and BHVI2 Plus 0.02% Atropine Eye Drops
To assess the one-month ocular effects of nightly application of experimental BHVI2 and 0.02% atropine eye drops either alone or in combination, in children aged between 6 to 13 years old with myopia and randomized to use of…
- Trial name
- NCT03690414
- Testing
- Experimental BHVI2, Atropine sulfate 0.02% eye drops, Combination eye drops
- Where
- Vietnam
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hai Yen Eye Care
Geographic Atrophy
A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)
The primary purpose of the study is to determine if IVT injections of vonaprument every month reduce vision loss in participants with dry AMD with GA.
- Trial name
- ARCHER II (NCT06510816)
- Testing
- Vonaprument
- Where
- 132 sites in United States, Australia and 12 more
- Volunteers
- 659 people
- Sponsor
- Annexon, Inc.
Photorefractive Keratectomy
Processed Amniotic Fluid (PAF) Drops After Photorefractive Keratectomy (PRK)
This is a randomized, double-masked, placebo-controlled study to determine the safety of pAF in patients who undergo PRK.
- Trial name
- NCT04281004
- Testing
- Amniotic Fluid (AFED), Saline Solution
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Utah
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