Clinical trials: Mask
Retinitis Pigmentosa (RP), Inherited Retinal Diseases
Study to Evaluate the Efficacy of a Single Intravitreal Injection of RTx-015 in Participants With Retinitis Pigmentosa (PERCEPT)
The purpose of this clinical trial is to evaluate the effectiveness and safety of a single injection into the eye of an investigational gene therapy in participants with retinitis pigmentosa (RP).
- Trial name
- PERCEPT (NCT07901751)
- Testing
- RTx-015
- Where
- 14 sites in United States
- Volunteers
- 60 people
- Sponsor
- Ray Therapeutics, Inc.
Influenza Infection
Catechin Containing Mask for the Prevention of Influenza Infection
The purpose of this study is to evaluate the effects of catechin extracts containing mask on prevention of influenza infection.
- Trial name
- NCT00812448
- Testing
- tea catechin extracts
- Where
- 2 sites in Japan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Shizuoka
Blepharitis
Safety and Efficacy of KPI-121 in Subjects With Inflammatory Meibomian Gland Disease
The primary purpose of this study is to determine the efficacy and safety of KPI-121 ophthalmic suspension compared to vehicle (placebo) in subjects with signs and symptoms of inflammatory meibomian gland disease.
- Trial name
- Maui (NCT02218489)
- Testing
- KPI-121, Vehicle
- Where
- 8 sites in United States
- Volunteers
- 206 people
- Sponsor
- Kala Pharmaceuticals, Inc.
Diabetic Macular Edema
A Comparison of Standard Laser With Micropulse Laser for the Treatment of Diabetic Macular Oedema.
DIAMONDS is a Randomised Controlled Clinical Trial that is being carried out in the UK to determine the clinical effectiveness and cost-effectiveness of micropulse laser, compared with standard laser, for the treatment of…
- Trial name
- DIAMONDS (NCT03690050)
- Testing
- Diode 577 nm subthreshold micropulse laser, Standard threshold laser (532 nm laser)
- Where
- 14 sites in United Kingdom
- Volunteers
- 266 people
- Sponsor
- Belfast Health and Social Care Trust
Allergic Conjunctivitis
A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat Allergy
This study is researching 2 experimental drugs, REGN1908 and REGN1909, which are called REGN1908-1909 when mixed together (called "study drug") to reduce eye allergy signs and symptoms from cat allergy.
- Trial name
- NCT06602726
- Testing
- REGN1908, REGN1909
- Where
- 4 sites in United States, Canada
- Volunteers
- 64 people
- Sponsor
- Regeneron Pharmaceuticals
Myopia, Myopia Progression
The P.A.U.S.E.® Spectacle Study
The goal of this clinical trial is to learn if spectacle lenses using Phase Alteration Utilising Sub Elements (P.A.U.S.E.®) technology works to slow down the rate of myopia progression in myopic children.
- Trial name
- NCT06577948
- Testing
- Single vision spectacle lens, P.A.U.S.E. spectacle lens 1, P.A.U.S.E. spectacle lens 2
- Where
- Vietnam
- Volunteers
- 205 people
- Sponsor
- nthalmic Pty Ltd
Cataract
Chloroprocaine 3% Gel Eye Drop as Topical Anestheticsin Phacoemulsification.
Randomized clinical trial, multicenter, two-armed, to investigate and compare the clinical efficacy of chloroprocaine 3% gel and tetracaine 0.5% eye drop as topical anestheticsin phacoemulsification.
- Trial name
- NCT04685538
- Testing
- Chloroprocaine 3%, Tetracaine 0.5%
- Where
- 27 sites in Italy, Slovakia and 1 more
- Volunteers
- 338 people
- Sponsor
- Sintetica SA
Primary Open Angle Glaucoma, Ocular Hypertension
Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular Hypertension
A Phase 3 Study Comparing the Efficacy and Safety of Netarsudil Ophthalmic Solution 0.02% QD to Ripasudil Hydrochloride Hydrate Ophthalmic Solution 0.4% BID, for Treatment of Primary Open-Angle Glaucoma or Ocular Hypertension…
- Trial name
- NCT04620135
- Testing
- Netarsudil ophthalmic solution 0.02%, Ripasudil hydrochloride hydrate ophthalmic solution 0.4%
- Where
- Japan
- Volunteers
- 245 people
- Sponsor
- Aerie Pharmaceuticals
Laryngeal Masks, Anesthesia, General
The Effect of Placement of Proseal Laryngeal Mask Airway With C-Mac Videolaryngoscopy
The ProSeal laryngeal mask airway (ProSeal LMA; Intavent Orthofix, Maidenhead, UK) is a device with a double cuff to improve the seal and a drain tube to help prevent aspiration and gastric insufflation, facilitate passage of a…
- Conditions
- Laryngeal Masks, Anesthesia, General, Videolaryngoscopy
- Trial name
- NCT03852589
- Testing
- C-MAC videolaryngoscope, Blind
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Inonu University
Geographic Atrophy Secondary to Age-related Macular Degeneration
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio
A Phase 2, Randomized, Placebo-controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL-3007 in Combination with Syfovre/Pegcetacoplan (APL-2) in Patients…
- Trial name
- NCT07215390
- Testing
- APL-3007, pegcetacoplan (APL-2)
- Where
- 78 sites in United States
- Volunteers
- 240 people
- Sponsor
- Apellis Pharmaceuticals, Inc.
Keratoconjunctivitis Sicca
To Assess the Safety and Efficacy of R932348 Ophthalmic Solutions in Patients With Keratoconjunctivitis Sicca
The purpose of this study is to determine whether 0.2% and 0.5% R348 Ophthalmic Solutions are safe and effective in the treatment of Patients with Keratoconjunctivitis Sicca.
- Trial name
- DROPS (NCT01900249)
- Testing
- R348 Ophthalmic Solution, 0.2%, R348 Ophthalmic Solution, 0.5%
- Where
- 20 sites in United States
- Volunteers
- 204 people
- Sponsor
- Rigel Pharmaceuticals
Skin Condition, Skin Hydration
Efficacy Test of a Moisturizing and Anti-aging Facial Mask
The objective of this study is to evaluate the effect of Moisturizing facial mask and Anti-aging facial mask on human skin condition improvement.
- Conditions
- Skin Condition, Skin Hydration, Anti Skin Aging
- Trial name
- NCT07622160
- Testing
- Hydrating Repairing Mask, Anti-aging Rejuvenating Mask
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Conjunctivitis, Allergic
Evaluation of the Onset and Duration of Action of Bepotastine Besilate Ophthalmic Solution in Acute Allergic Conjunctivitis
The purpose of this study is to evaluate whether bepotastine besilate ophthalmic solution is effective in the treatment of acute allergic conjunctivitis
- Trial name
- NCT00424398
- Testing
- Bepreve, Bepotastine Besilate
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Bausch & Lomb Incorporated
Macular Degeneration
A Safety Study to Evaluate Pazopanib Eye Drops in Healthy Volunteers
A study to determine the safety and tolerability of pazopanib eye drops. The study will also determine how the drug is absorbed and metabolized over time.
- Trial name
- NCT01072214
- Testing
- pazopanib
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Neonatal Mortality, Cord Care
Chlorhexidine Cordcare for Reduction in Neonatal Mortality and Omphalitis
In a community-based controlled trial among children to evaluate if use of 4% Chlorhexidine cleansing solution on umbilical cord of infants in first 10 days of life results in Reduction in neonatal mortality (deaths in first 28…
- Conditions
- Neonatal Mortality, Cord Care, Omphalitis
- Trial name
- CHX-Pemba (NCT01528852)
- Testing
- Chlorhexidine 4%, Control cord cleaning solution
- Where
- Tanzania
- Volunteers
- 36,911 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Dry Eye
An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
The purpose of this study is to determine the safety and efficacy of VSJ-110 compared to placebo in the treatment of dry eye.
- Trial name
- NCT07179055
- Testing
- VSJ-110
- Where
- 5 sites in United States
- Volunteers
- 160 people
- Sponsor
- Vanda Pharmaceuticals
Exudative Age-Related Macular Degeneration, Focal Vitreomacular Adhesion
Safety and Efficacy Study of Intravitreal Ocriplasmin in Subjects With AMD With Focal Vitreomacular Adhesion
This study will evaluate the safety and efficacy of Ocriplasmin intravitreal injection, in subjects diagnosed with exudative AMD with focal vitreomacular adhesion.
- Trial name
- MIVI-5 (NCT00913744)
- Testing
- Ocriplasmin
- Where
- 27 sites in United States, Belgium and 4 more
- Volunteers
- 100 people
- Sponsor
- ThromboGenics
Fine Lines and Wrinkles, Skin Health
Efficacy of an LED Mask
The goal of this interventional study is to evaluate the efficacy and perception a commercial LED device in 110 healthy adult females and males between the ages of 35-65 years old, inclusively.
- Conditions
- Fine Lines and Wrinkles, Skin Health, Skin Tone
- Trial name
- NCT07890233
- Testing
- Light emitting diode treatment
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Therabody, Inc.
Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy
Effects of Face Mask Continuous Positive Airway Pressure Vs. Noninvasive Ventilation Vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: the TRIPOD Randomized Clinical Trial
Acute hypoxemic respiratory failure (AHRF) is a common indication for admission to an intensive care unit (ICU), with mortality exceeding 50% in cases where invasive mechanical ventilation is needed.
- Conditions
- Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy, Noninvasive Ventilation, Continuous Positive Airway Pressure (CPAP)
- Trial name
- TRIPOD (NCT06795971)
- Testing
- Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Southeast University, China
Respiratory Physiology, Respiratory Insufficiency
Investigation of Efficiency of Breathing With Different Breathing Patterns
Our aim in this study is to investigate the efficiency of the breathing with different breathing patterns. Ten volunteers and twenty patients having respiratory problems will be coached on their breathing through specific masks…
- Conditions
- Respiratory Physiology, Respiratory Insufficiency, Breathing Patterns
- Trial name
- NCT00784004
- Testing
- Breathing Patterns
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.