Clinical trials: Massive Rotator Cuff Tear, open to volunteers
Massive Rotator Cuff Tears
Latissimus Dorsi Tendon Transfer vs. Superior Capsular Reconstruction in Massive Rotator Cuff Tears
The goal of this clinical trial is to compare the results of two surgical operations for the treatment of massive rotator cuff tears: latissimus dorsi tendon transfer (LDT) and superior capsular reconstruction (SCR).
- Trial name
- NCT07154641
- Testing
- Latissimus dorsi tendon transfer, Superior capsular reconstruction
- Where
- Greece
- Volunteers
- 44 people
- Sponsor
- Konstantopoulio-Patission General Hospital of Nea Ionia
Massive Rotator Cuff Tears, Massive Rotator Cuff Tear
Voll Non-Degradable Shoulder Spacer FIH Study
The Voll Non-Degradable Shoulder Spacer First-in-Human study aims to evaluate the initial safety, effectiveness, and clinical outcomes of a non-degradable shoulder spacer in over 50 years old patients with symptomatic massive…
- Trial name
- NCT07745647
- Testing
- Voll Non-Degradable Shoulder Spacer
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Voll Medical Technologies Ltd.
Massive Rotator Cuff Tear
Voll Degradable Shoulder Spacer FIH Study
The Voll Degradable Shoulder Spacer First-in-Human study aims to evaluate the initial safety, effectiveness, and clinical outcomes of a degradable shoulder spacer in over 50 years old patients with symptomatic massive rotator…
- Trial name
- NCT07208448
- Testing
- Voll Degradable Shoulder Spacer
- Where
- 4 sites in Israel, Italy
- Volunteers
- 20 people
- Sponsor
- Voll Medical Technologies Ltd.
Rotator Cuff Tears, Bioinductive Implant
Maximal Repair Versus Bridging Reconstruction with BioBrace®
The purpose of this study is to determine if using BioBrace® to reconstruct the gap in the rotator cuff tears lead to better results for patients compared to the traditional maximal repair method.
- Trial name
- NCT05959733
- Testing
- Bridging Reconstruction using BioBrace, Repair
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Nova Scotia Health Authority
Rotator Cuff Tears
Acellular Matrix From Human Dermis in Combination With Orthobiologic Stimuli for Augmentation of Massive Rotator Cuff Tears
The use of biologic acellular matrices for the surgical augmentation of rotator cuff lesions has greatly expanded inrecent years.
- Trial name
- MODA (NCT05855759)
- Testing
- Acellular Dermal Matrix, Acellular Dermal Matrix with autologous orthobiologics
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Istituto Ortopedico Rizzoli
Rotator Cuff Injuries, Rotator Cuff Tears
Slow and Accelerated Rehabilitation Protocols
Latissimus dorsi transfer is an established treatment option with favorable results in massive, irreparable rotator cuff tears, however, it is controversial if earlier motion is detrimental or beneficial to the postoperative goal…
- Conditions
- Rotator Cuff Injuries, Rotator Cuff Tears, Pain, Shoulder
- Trial name
- NCT05450510
- Testing
- Accelerated (ACCEL) protocol group, Slow (SLOW) protocol group
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Hacettepe University
Massive Rotator Cuff Tear
Effects Of Biceps Transposition Without Tenotomy For Augmentation Of Massive Rotator Cuff Repairs
This prospective, single-arm interventional study will evaluate the effects of long head of the biceps tendon (LHBT) transposition without tenotomy as an augmentation technique for arthroscopic partial repair in adults with…
- Trial name
- ROTATORCUFF (NCT07375277)
- Testing
- LHBT Transposition Augmentation
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Balikesir Ataturk City Hospital
Rotator Cuff Disease
Arthroscopic Rotator Cuff Repair with UC-MSCs for Large to Massive Tears
Safety Analysis of Allogeneic Umbilical Cord-Derived Mesenchymal Stem Cells in Patients Undergoing Rotator Cuff Repair for Massive or Large Rotator Cuff Tears
- Trial name
- NCT06817616
- Testing
- Injection allogenic Umbilical Cord-derived Mesenchymal Stem Cell
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Korea University Anam Hospital
Early Retears and Clinical Outcomes Following Surgical Repair of Massive Rotator Cuff Tears
Postoperative USG Control and Clinical Follow-up of Massive Rotator Cuff Tendon Ruptures
This prospective observational study aims to investigate the tendon integrity and clinical outcomes following surgical repair of massive rotator cuff tears.
- Trial name
- NCT07004218
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Massive Rotator Cuff Tears
Arthroscopic Treatment of Massive Rotator Cuff Tears With Debridement and Biodegradable Spacer.
Massive rotator cuff tears are common in the adult population. It is estimated that about 12 % of adults 60 years of age or older suffer from a rotator cuff injury.
- Trial name
- AMRIS (NCT04571918)
- Testing
- Biodegradable spacer, Debridement and biceps tenotomy
- Where
- 2 sites in Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Rotator Cuff Tears, Rotator Cuff Injuries
Arthroscopic Rotator Cuff Repair With Long Head of Biceps Transposition and Acellular Dermal Matrix Augmentation for Large to Massive Incompletely Repairable Rotator Cuff Tears
Large-to-massive rotator cuff tears of the shoulder with poor tendon and muscle quality often cannot be fully repaired back to its footprint, and they have a high risk of re-tear.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Massive Rotator Cuff Tear
- Trial name
- SCR-ADM-repair (NCT07875556)
- Testing
- Rotator Cuff Repair, Long Head of the Biceps Tendon Transposition, Acellular Dermal Matrix (Allograft) Augmentation
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Tam Anh Research Institute
Rotator Cuff Tear
Superior Capsular Reconstruction vs. Partial Repair for Massive Rotator Cuff Tears
Little evidence exists to guide treatment in patients with massive irreparable rotator cuff tears (MRCTS). Arthroscopic partial rotator cuff repair (PRCR) has the longest record of use.
- Trial name
- SCR (NCT03617562)
- Testing
- Superior Capsular Reconstruction, Partial Repair
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Sunnybrook Health Sciences Centre
Rotator Cuff Tears
RSA Vs RCR for Massive RCTs
Different treatment options are available for massive or irreparable rotator cuff tears. An arthroscopic or an open repair approach is possible in the majority of cases and functional outcomes are improved, particularly when a…
- Trial name
- NCT05807854
- Testing
- Arthroscopy, Reverse Shoulder Arthroplasty
- Where
- 2 sites in United States, Switzerland
- Volunteers
- 160 people
- Sponsor
- La Tour Hospital
Rotator Cuff Tears
InSpace Accelerated Rehabilitation Study
This is a prospective, parallel group, open-label, multi- center, randomized study to assess two accelerated rehabilitation programs for use with the InSpace device in the treatment of full thickness Massive, Irreparable Rotator…
- Trial name
- iAccelerate (NCT05329584)
- Testing
- InSpace Subacromial Tissue Spacer
- Where
- 11 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Stryker Endoscopy
Rotator Cuff Injuries
Evaluation Of Outcomes Following Rotator Cuff Repair Using the REGENETEN Bioinductive Implant
This prospective, single-arm, multicenter registry is being conducted to collect real world post-market data from patients who are undergoing rotator cuff repair using the REGENETEN◊ Bioinductive Implant System.
- Trial name
- RePaRe (NCT06857084)
- Testing
- Arthroscopic rotator cuff repair with REGENETEN Bioinductive Implant augmentation
- Where
- 22 sites in Australia, Germany and 2 more
- Volunteers
- 400 people
- Sponsor
- Smith & Nephew, Inc.
Massive Rotator Cuff Tear
Lower Trapezius Tendon Transfer vs Partial Cuff Repair in Massive Rotator Cuff Tears
Very large tears of the shoulder tendons (the 'rotator cuff') that are not surgically repairable and in the absence of significant shoulder arthritis are common in older patients, and are associated with significant pain and…
- Trial name
- TENET (NCT07051889)
- Testing
- Lower Trapezius Tendon Transfer, Partial Rotator Cuff Repair
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ottawa Hospital Research Institute
Rotator Cuff Tears, Rotator Cuff Syndrome
Outcomes of Massive Rotator Cuff Tendon Tear Treatment.
Rotator cuff tear is the leading cause of shoulder pain in the elderly. There isn't enough evidence nor clinical guidelines to guide the treatment of massive rotator cuff tears, specially irreparable tears.
- Trial name
- NCT06016439
- Testing
- Arthroscopic rotator cuff partial repair with superior capsular augmentation with LHBBT, Arthroscopic rotator cuff partial repair, Arthroscopic complete rotator cuff repair
- Volunteers
- 80 people
- Sponsor
- Tartu University Hospital