Clinical trials: Mastectomy
Modified Radical Mastectomy
Adding Magnesium Sulfate to Combined Pecto-Intercostal & Serratus Anterior Planes Block on Post-operative Analgesia in Patients Undergoing Modified Radical Mastectomy
Here, in our study, we intend to compare the analgesic efficacy of magnesium sulfate as an adjuvant to local anesthetics added to the Pecto-Intercostal Fascial Block (PIFB) vs the Serratus Anterior Plane Block (SAPB) in patients…
- Trial name
- Mastectomy (NCT07434232)
- Testing
- combined Pecto-Intercostal- Serratus anterior fascial planes Block
- Volunteers
- 100 people
- Sponsor
- South Egypt Cancer Institute
Mastectomy and Breast Reconstruction, Tissue Expander Based Breast Reconstruction
Comparison of Mastectomy Expander Trial
Expanders are used outside their intended use, due to two following facts: It is possible that expander implantation exceed the "approved" duration of 6 months (maximal 10 months).
- Conditions
- Mastectomy and Breast Reconstruction, Tissue Expander Based Breast Reconstruction, Adjuvant Radiotherapy, Long Term Outcome
- Trial name
- COMMET (NCT07434648)
- Testing
- intervention (unilateral/bilateral), scheduled for (NSME/SSME), indication (breast cancer diagnosis (malignancy) with neoadjuvant chemotherapy or DCIS diagnosis without neoadjuvant chemotherapy
- Volunteers
- 80 people
- Sponsor
- Medical University Innsbruck
Mastectomy, Peripheral Nerve Block
Comparison of the Postoperative Analgesic Effects of SPSIPB and TPB in Mastectomy Operations
Breast cancer is the most common malignancy in women, and surgery is one of the cornerstone treatments for breast cancer. Postoperative pain can significantly reduce patients' quality of life and acute pain may even trigger…
- Conditions
- Mastectomy, Peripheral Nerve Block, Pain Management
- Trial name
- NCT06789146
- Testing
- Serratus posterior superior intercostal plane block, Thoracic Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Amantadine, Duloxetine
Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
This study aims to evaluate the additive effect of Amantadine or Duloxetine to Pregabalin on development of post mastectomy pain syndrome
- Conditions
- Amantadine, Duloxetine, Pregabalin, Mastectomy
- Trial name
- NCT07421427
- Testing
- Pregabalin, Pregabalin + Amantadine, Pregabalin + Duloxetine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Mastectomy, Pain, Acute
Stellate Ganglion Block for Prevention of Post Mastectomy Depression
Complications after mastectomy include chronic pain and depression.
- Conditions
- Mastectomy, Pain, Acute, Pain, Chronic
- Trial name
- SGB (NCT06263907)
- Testing
- Stellate gangalion block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Mansoura University
Breast Cancer, Mastectomy; Lymphedema
Breast Reconstruction by Exclusive Lipomodulin : Feasibility, Evaluation of the Aesthetic Result and Quality of Life
Breast cancer is the leading female cancer in metropolitan France in terms of incidence and death. Among the therapeutic arsenal for the treatment of these cancers, surgery plays a very important role and even if a conservative…
- Trial name
- EXCLUFAT (NCT04625621)
- Where
- France
- Volunteers
- 118 people
- Sponsor
- Institut Cancerologie de l'Ouest
Mastectomy
A Prospective Study of Video-assisted Exercise Program for the Breast Cancer Survivors
The investigators cancer rehabilitation/recovery program, Strong Survivor, has been designed to be delivered digitally, and while there are many such programs currently available on the internet, especially in the time of…
- Trial name
- StrongSurvivor (NCT07071896)
- Testing
- 16 weeks remotely exercise program
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Diego
Breast Cancer, Post Mastectomy
Breast Fractionation Study - Standard Versus Investigational Fractionation Trial - Nodal Radiation
The purpose of this study is to investigate the difference in fatigue, quality of life and radiation morbidity between hypofractionated and conventional radiation to the breast, chest wall and regional lymph nodes post mastectomy…
- Trial name
- NCT04909125
- Testing
- Hypofractionated radiotherapy VS Standard/Conventional fractionation radiotherapy
- Where
- Australia
- Volunteers
- 132 people
- Sponsor
- Royal North Shore Hospital
Breast Cancer, Modified Radical Mastectomy
Ultrasound-Guided PEC I vs SAP Block for Postoperative Analgesia in Modified Radical Mastectomy
This randomized double-blind controlled clinical trial was conducted to compare the analgesic efficacy of ultrasound-guided Pectoral Nerve Block versus Serratus Anterior Plane Block in female patients undergoing Modified Radical…
- Conditions
- Breast Cancer, Modified Radical Mastectomy, Pectoral Nerve Blocks, Serratus Anterior Plane Block
- Trial name
- PECS I vs SAP (NCT07388238)
- Testing
- Ultrasound-Guided Pectoral Nerve Block (PECS I), Ultrasound-Guided Serratus Anterior Plane Block (SAPB)
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Ain Shams University
Mastectomy and Breast Reconstruction, Sexual Wellness
Sexual Well-being of Women Undergoing Mastectomy and Reconstruction
The study plans to collect data from patients on sexual well-being after mastectomy and immediate reconstruction by surveys. This data can support preoperative patient counselling and the prevention and care of adverse effects of…
- Trial name
- NCT07234461
- Testing
- Survey using a questionnaire.
- Where
- 19 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- European Institute of Oncology
Chronic Low-back Pain, Mastectomy
EMG Biofeedback Treatment for Chronic Low Back Pain, Cancer Pain and Migraines
The purpose of this pilot efficacy study is to examine the effects of EMG-biofeedback (EMG-BF) on pain-related outcomes in Chronic Low Back Pain (CLBP) patients, Recent mastectomy and lumpectomy patients, and patients with…
- Conditions
- Chronic Low-back Pain, Mastectomy, Lumpectomy, Migraine
- Trial name
- BEAT-Pain (NCT04607460)
- Testing
- JOGO Digital Therapeutics EMG Biofeedback for Lower Back Pain, JOGO Digital Therapeutics EMG Biofeedback for Persistent Post Mastectomy Pain, JOGO Digital Therapeutics EMG Biofeedback for Migraine
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Brigham and Women's Hospital
Mastectomy Patient
Bi-level Erector Spinae Plane Block and Pre-emptive Oral Tizanidine for Analgesia After Mastectomy Surgery
Effective management of postoperative pain in breast cancer surgery is essential to minimize the risk of developing postmastectomy pain syndrome.The aim of this study is to evaluate the effectiveness of combining bilevel erector…
- Trial name
- NCT07022353
- Testing
- Bilevel erector spinae plane block, tizanidine oral capsule
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Costotransverse Foramen Block, Erector Spinae Plane Block
Costotransverse Foramen Block With Erector Spinae Plane Block in Modified Radical Mastectomy
This study aims to compare the costotransverse foramen block with erector spinae plane block in modified radical mastectomy.
- Conditions
- Costotransverse Foramen Block, Erector Spinae Plane Block, Modified Radical Mastectomy
- Trial name
- NCT07367568
- Testing
- Costotransverse foramen block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer, Breast Reconstruction After Mastectomy
Study on the Cosmetic Outcome and Safety Evaluation of 3D Printed Biodegradable Biological Mesh for One-Stage Breast Reconstruction After Radical Mastectomy
Primary objective of this trial: To evaluate the clinical performance (aesthetic outcome and quality of life) and safety of a 3D-printed biodegradable biological mesh in post-mastectomy immediate breast reconstruction.
- Conditions
- Breast Cancer, Breast Reconstruction After Mastectomy, 3D-Printed Biodegradable Biological Mesh
- Trial name
- NCT07365267
- Testing
- Implantation of a silicone breast prosthesis combined with a 3D-printed biodegradable mesh
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Xijing Hospital
Breast Cancer, Sentinel Lymph Node Biopsy (SLNB)
Finding Sentinel Lymph Nodes During Mastectomy Using Indocyanine Green (INIGMA Study)
This pilot study evaluates the diagnostic value of indocyanine green (ICG) fluorescence for sentinel lymph node biopsy (SLNB) performed through the mastectomy incision in breast cancer patients.
- Conditions
- Breast Cancer, Sentinel Lymph Node Biopsy (SLNB), Sentinel Lymph Node Detection, Sentinel Lymph Node
- Trial name
- INIGMA (NCT07362485)
- Testing
- Indocyanine green (ICG)-fluorescence guided sentinel lymph node biopsy
- Where
- 2 sites in Netherlands
- Volunteers
- 90 people
- Sponsor
- Isabelle Henskens
Osteoporosis, Mastectomy
Effect of Wii Fit Balance Board Games on Balance in Patients With Osteoporosis Post Mastectomy
This study will be a randomized controlled trial. The purpose of the study is to evaluate the therapeutic effect of Wii Fit balance board games on balance in patients with osteoporosis post mastectomy.
- Trial name
- NCT07364279
- Testing
- Wii fit balance board, traditional balance exercise, Calcium supplement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Breast Neoplasms, Mastectomy; Lymphedema
Self-Affirmation Intervention After Mastectomy
This randomized controlled trial aims to evaluate the effect of a structured self-affirmation intervention on pain, depression, anxiety, and stress levels in patients undergoing mastectomy.
- Conditions
- Breast Neoplasms, Mastectomy; Lymphedema, Pain, Depression
- Trial name
- NCT07355244
- Testing
- Positive Self-Affirmation Audio with Calming Background Sounds
- Volunteers
- 42 people
- Sponsor
- Muş Alparslan University
Breast Neoplasms, Mastectomy, Segmental
Acellular Dermal Matrix(SureDerm BCS) in Breast-Conserving Surgery for Breast Cancer Patients
The goal of this clinical trial is to evaluate whether the use of an acellular dermal matrix (SureDerm) can improve cosmetic satisfaction and is safe in women with breast cancer undergoing breast-conserving surgery.
- Trial name
- NCT07345026
- Testing
- Acellular Dermal Matrix (SureDerm BCS), Standard Breast-Conserving Surgery
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Seoul St. Mary's Hospital
Mastectomy; Lymphedema, Breast Cancer
Polyurethan Versus Non-polyurethan Covered Implants in Combination With Radiotherapy
The purpose of this multicenter retrospective cohort study is to determine the effect of radiotherapy on capsular contraction and implant loss rates in patients undergoing prepectoral immediate implant-based breast reconstruction…
- Trial name
- PRExRT (NCT06747065)
- Testing
- Radiotherapy
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Post Mastectomy
Sensorimotor Training Exercises for Shoulder Position Sense
Forty-six female patients aged 35-55 years who were suffering from shoulder dysfunction following mastectomy surgeries participated in this study.
- Trial name
- NCT07316283
- Testing
- Sensorimotor Training Exercises, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University