Clinical trials: Mastication, open to volunteers
Head and Neck Cancer
Evolution of Masticatory Function, Orofacial Functions and Quality of Life of Patients Treated for Cancers of the Upper Aerodigestive Tract, Rehabilitated by Maxillofacial Prostheses.
This is a follow-up study of masticatory function, orofacial functions, and quality of life in patients with a history of upper aerodigestive tract cancer who have undergone rehabilitation with maxillofacial prostheses.
- Trial name
- RMF-CROC (NCT07471451)
- Testing
- Prosthetic oral rehabilitation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Orthodontic Appliances
Orthodontic Pain Alleviation With Chewing Gum
The aim of this study is to determine whether chewing gum can alleviate orthodontic treatment discomfort and improve orthodontic treatment experience.
- Trial name
- NCT07210697
- Testing
- Xylitol Gum
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- West Virginia University
Mastication, Disability
Orofacial Functions and Masticatory Function in Children With Different Types of Deterioration in Oral Health
This project aims at studying the evolution of masticatory function (food bolus granulometry, masticatory behavior, muscle activity and masticatory performance) during oral rehabilitation, in children with different types of oral…
- Conditions
- Mastication, Disability, Oral Stage, Child Development
- Trial name
- KIDYCROC (NCT05821140)
- Testing
- dental treatment for global oral rehabilitation, oral health check up
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Clermont-Ferrand
Molar-Incisor Hypomineralization (MIH), Masticatory Performance
Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization
This study aims to evaluate right-left chewing balance and masticatory function in children with Molar-Incisor Hypomineralization (MIH) before and after restorative treatment.
- Conditions
- Molar-Incisor Hypomineralization (MIH), Masticatory Performance, Occlusal Analysis, Chewing Function
- Trial name
- NCT07589179
- Testing
- Glass Hybrid Restorative Treatment
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Marmara University
Malocclusion
Comparison of Acupressure, Ibuprofen, and Chewing Gum for the Management of Post-Archwire Orthodontic Pain
The goal of this clinical trial is to find out which method works best to reduce pain after braces are adjusted for the first time (when the first archwire is placed).
- Trial name
- NCT07638644
- Testing
- Acupressure, Ibuprofen 400 mg (if necessary), Chewing Gum
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Bahria University
Oral Health Care
Effects of a Salivary Gland Massage Program on Salivary Flow , Xerostomia, Chewing, and Swallowing, and Oral Health Among Community- Dwelling Older Adults
Purpose: This study aims to evaluate the effectiveness of salivary gland massage on saliva flow, xerostomia, chewing and swallowing, and oral health among community-dwelling elderly.
- Trial name
- NCT07251543
- Testing
- Salivary gland massage, General Oral Health Education
- Where
- Taiwan
- Volunteers
- 108 people
- Sponsor
- Chiayi Christian Hospital
TMD/Orofacial Pain, Myalgia of Mastication Muscle
Botulinum Toxin in the Management of Temporo-mandibular Related Myalgia: a Prospective Study
The aim of this study was to evaluate the clinical course in terms of pain, function and quality of life of patients with TMD-related myalgia during six months after receiving BTX-A injections.
- Conditions
- TMD/Orofacial Pain, Myalgia of Mastication Muscle, Botulinum Toxin, Type a
- Trial name
- BOMAMY (NCT06677216)
- Testing
- Botulinum Toxin, Type A
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Diakonessenhuis, Utrecht
Hypersialorrhea (Excessive Salivation), Psychiatric Disorders
Chewing Gum as a Therapeutic Intervention for the Management of Hypersalivation
Psychiatric disorders often require specific treatments, usually involving medications called psychotropic drugs. While effective, these medications can cause significant side effects.
- Trial name
- Chew Daily (NCT07158359)
- Testing
- chewing gum mastication
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cadillac
Chewing Efficiency in Completely Edentulous Patients Rehabilitated With Implant-Supported Full-Arch Prostheses
Dynamic vs. Static Jaw Relations in Implant-Supported Prostheses: Chewing Efficiency
This study aims to compare the chewing efficiency of implant-supported full-arch prostheses fabricated using two different jaw relation registration techniques: conventional static jaw relation registration and dynamic jaw…
- Trial name
- NCT07890389
- Testing
- Conventional Static Jaw Relation Registration, Dynamic Digital Jaw Tracking Registration
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Patient Satisfaction
This Study Will Assess Whether the Treatment Provided by Dentist is Successful in Meeting the Expectations of Patient by Asking Questions Related to Aesthetics, Chewing Ability, Comfort and Phonetics Before and After Providing Treatment and the Patient Will Tell Through Visual Analog Scale
This study aims to assess patient satisfaction after receiving porcelain-fused-to-metal fixed dental prostheses. Patients will be asked about their expectations before treatment and their satisfaction afterward.
- Trial name
- NCT07100678
- Testing
- Porcelain-Fused-to-Metal Fixed Dental Prosthesis
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Khyber College of dentistry
Smoking Cessation
Gen AI Powered Behavioral Support Plus Chewing Gum Intervention for Construction Workers Who Smoke
The goal of this pilot trial is to learn if 1-week NRT sampling, 3-week chewing gum, and 12-week chatbot-delivered instant messaging support works to help smoking cessation in construction workers who smoke.
- Trial name
- NCT07649018
- Testing
- AWARD advice, Brief leaflet on health warning and smoking cessation, Referral card
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Edentulism Complete, Denture, Complete
Nutritional Intervention for Older Adults With Complete Dentures
The purpose of this clinical trial is to test a nutritional intervention. This study helps older adults who wear complete removable dentures improve their health.
- Conditions
- Edentulism Complete, Denture, Complete, Mastication Disorder
- Trial name
- NCT07692828
- Testing
- Nutritional Intervention
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad de La Frontera
Systemic Sclerosis (SSc), Scleroderma
Patients Diagnosed With Scleroderma and Their Chewing and Swallowing Performance
It is recommended to focus on the physical functionality, chewing, and swallowing performance of individuals diagnosed with scleroderma.
- Conditions
- Systemic Sclerosis (SSc), Scleroderma, Scleroderma (Limited and Diffuse), Scleroderma, Localized
- Trial name
- NCT07182981
- Testing
- Questionnaire application for child and adult scleroderma patients
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Edentulism
3D-Printed Implant Overdentures: Comparing Impression Techniques
This randomized crossover clinical trial aims to compare three different impression techniques for the construction of 3d-printed mandibular implant overdentures in completely edentulous patients.
- Trial name
- NCT07208812
- Testing
- Conventional open -tray impression, Functionally generated reline impression, Mucostatic base with functional borders impression
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Type 2 Diabetes
Effect of Molar Replacement on Glycemic Control in Adults With Uncontrolled Type 2 Diabetes
Type 2 diabetes (T2D) is a major global health issue, affecting about 9.2% of adults in Europe. Although treatment begins with lifestyle changes and medications, up to half of patients fail to achieve adequate blood sugar…
- Trial name
- DIABETEETH (NCT07666529)
- Testing
- Replacement of one pair of molars
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle
Occlusal Equilibration vs. Sham Therapies for TMDs: Post-Trial Follow-up (OEST)
Chronic temporomandibular disorders (TMDs) affect the masticatory muscles, the temporomandibular joints (TMJs), and associated structures. Except in cases of trauma, their etiology remains uncertain, debated, and multifactorial.
- Conditions
- Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle, Arthralgia Syndrome
- Trial name
- OEST (NCT07445516)
- Where
- 2 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Urbano Santana Penin
Completely Edentulous Patients
Stabilizing Mandibular Overdentures With a Single Implant Placed in the Canine Region of the Preferred Chewing Side
The investigators are evaluating the use of a single implant to stabilize complete dentures in the lower jaw, in the canine region of the preferred chewing side.
- Trial name
- c-SIMO (NCT06755034)
- Testing
- c-SIMO, m-SIMO
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Frauke Müller
Dental Plaque Accumulation
4-day Plaque Accumulation Model Evaluating Compound Containing Gum
This will be a single-blind, single-center, 3-way crossover, randomized controlled clinical trial with 3 treatment periods utilizing 32 subjects.
- Trial name
- NCT06984744
- Testing
- MIIP-E2 containing gum
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Lactea Therapeutics, LLC
Mastication Disorder, Fatigue
Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT).
Temporomandibular Disorders (TMD) encompass various conditions that affect the temporomandibular joint and associated tissues, often causing or being associated with other symptoms such as jaw pain, myofascial pain, neck pain…
- Conditions
- Mastication Disorder, Fatigue, Temporomandibular Disorder, Orofacial Pain
- Trial name
- F-6MMT (NCT06298786)
- Testing
- Functional 6-minute mastication test
- Where
- 3 sites in Spain
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- Fundació Universitària del Bages
Postoperative Nausea and Vomiting (PONV), Peritoneal Metastases From Colorectal Cancer
Chewing Gum Flavors to Reduce Postoperative Nausea and Vomiting After PIPAC
This randomized controlled clinical trial aims to evaluate the effectiveness of chewing gum with different natural flavors in reducing postoperative nausea and vomiting (PONV) following Pressurized IntraPeritoneal Aerosol…
- Conditions
- Postoperative Nausea and Vomiting (PONV), Peritoneal Metastases From Colorectal Cancer, Intraperitoneal Chemotherapy
- Trial name
- NCT07315412
- Testing
- Ginger-Mint Chewing Gum, Cinnamon Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Fenerbahce University