Clinical trials: Mastication, open to volunteers
Face
Effects of Hard Gum Chewing on Facial Soft Tissue Morphology
This pilot clinical trial will evaluate whether intentional chewing of a standardized hard chewing gum for 4 weeks produces measurable changes in facial morphology in healthy adults.
- Trial name
- GUM-3D (NCT07726511)
- Testing
- Hard Gum Chewing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- UConn Health
Endodontically Treated Teeth
Bite Force and Occlusal Force Distribution Following Root Canal Treatment.
Understanding the changes in bite force and occlusal force distribution in ETT is clinically important, as it can directly influence tooth prognosis, guide restorative treatment planning, and impact the long-term survival of the…
- Trial name
- B-FORCE RCT (NCT07626372)
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Edentulism
3D-Printed Implant Overdentures: Comparing Impression Techniques
This randomized crossover clinical trial aims to compare three different impression techniques for the construction of 3d-printed mandibular implant overdentures in completely edentulous patients.
- Trial name
- NCT07208812
- Testing
- Conventional open -tray impression, Functionally generated reline impression, Mucostatic base with functional borders impression
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pain, Anxiety
Effects of Music Application and Gum Chewing on Pain, Anxiety, and Patient Satisfaction During Episiotomy Repair
Lacerations and episiotomies are serious procedures requiring surgical stitches. Therefore, pain occurs during episiotomy repair. Pain during episiotomy repair also causes anxiety, which in turn exacerbates pain.
- Conditions
- Pain, Anxiety, Patient Satisfaction
- Trial name
- NCT07323758
- Testing
- Music, Gum Chewing
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Patient Satisfaction
This Study Will Assess Whether the Treatment Provided by Dentist is Successful in Meeting the Expectations of Patient by Asking Questions Related to Aesthetics, Chewing Ability, Comfort and Phonetics Before and After Providing Treatment and the Patient Will Tell Through Visual Analog Scale
This study aims to assess patient satisfaction after receiving porcelain-fused-to-metal fixed dental prostheses. Patients will be asked about their expectations before treatment and their satisfaction afterward.
- Trial name
- NCT07100678
- Testing
- Porcelain-Fused-to-Metal Fixed Dental Prosthesis
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Khyber College of dentistry
Edentulism Complete, Denture, Complete
Nutritional Intervention for Older Adults With Complete Dentures
The purpose of this clinical trial is to test a nutritional intervention. This study helps older adults who wear complete removable dentures improve their health.
- Conditions
- Edentulism Complete, Denture, Complete, Mastication Disorder
- Trial name
- NCT07692828
- Testing
- Nutritional Intervention
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad de La Frontera
Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle
Occlusal Equilibration vs. Sham Therapies for TMDs: Post-Trial Follow-up (OEST)
Chronic temporomandibular disorders (TMDs) affect the masticatory muscles, the temporomandibular joints (TMJs), and associated structures. Except in cases of trauma, their etiology remains uncertain, debated, and multifactorial.
- Conditions
- Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle, Arthralgia Syndrome
- Trial name
- OEST (NCT07445516)
- Where
- 2 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Urbano Santana Penin
Hypersialorrhea (Excessive Salivation), Psychiatric Disorders
Chewing Gum as a Therapeutic Intervention for the Management of Hypersalivation
Psychiatric disorders often require specific treatments, usually involving medications called psychotropic drugs. While effective, these medications can cause significant side effects.
- Trial name
- Chew Daily (NCT07158359)
- Testing
- chewing gum mastication
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cadillac
TMD/Orofacial Pain, Myalgia of Mastication Muscle
Botulinum Toxin in the Management of Temporo-mandibular Related Myalgia: a Prospective Study
The aim of this study was to evaluate the clinical course in terms of pain, function and quality of life of patients with TMD-related myalgia during six months after receiving BTX-A injections.
- Conditions
- TMD/Orofacial Pain, Myalgia of Mastication Muscle, Botulinum Toxin, Type a
- Trial name
- BOMAMY (NCT06677216)
- Testing
- Botulinum Toxin, Type A
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Diakonessenhuis, Utrecht
Postoperative Nausea and Vomiting (PONV), Peritoneal Metastases From Colorectal Cancer
Chewing Gum Flavors to Reduce Postoperative Nausea and Vomiting After PIPAC
This randomized controlled clinical trial aims to evaluate the effectiveness of chewing gum with different natural flavors in reducing postoperative nausea and vomiting (PONV) following Pressurized IntraPeritoneal Aerosol…
- Conditions
- Postoperative Nausea and Vomiting (PONV), Peritoneal Metastases From Colorectal Cancer, Intraperitoneal Chemotherapy
- Trial name
- NCT07315412
- Testing
- Ginger-Mint Chewing Gum, Cinnamon Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Fenerbahce University
Mastication Disorder, Fatigue
Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT).
Temporomandibular Disorders (TMD) encompass various conditions that affect the temporomandibular joint and associated tissues, often causing or being associated with other symptoms such as jaw pain, myofascial pain, neck pain…
- Conditions
- Mastication Disorder, Fatigue, Temporomandibular Disorder, Orofacial Pain
- Trial name
- F-6MMT (NCT06298786)
- Testing
- Functional 6-minute mastication test
- Where
- 3 sites in Spain
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- Fundació Universitària del Bages
Oral Health Care
Effects of a Salivary Gland Massage Program on Salivary Flow , Xerostomia, Chewing, and Swallowing, and Oral Health Among Community- Dwelling Older Adults
Purpose: This study aims to evaluate the effectiveness of salivary gland massage on saliva flow, xerostomia, chewing and swallowing, and oral health among community-dwelling elderly.
- Trial name
- NCT07251543
- Testing
- Salivary gland massage, General Oral Health Education
- Where
- Taiwan
- Volunteers
- 108 people
- Sponsor
- Chiayi Christian Hospital
Healhty
Chewing, Eating Rate, and Weight Status in Children
Background: Childhood obesity is a multifactorial health condition associated with profound metabolic, psychosocial, and socioeconomic ramifications across the lifespan.
- Trial name
- CHEW-KIDS (NCT07808983)
- Testing
- Test meal B, Test meal A
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ariel University
Nutritional and Metabolic Diseases, Overweight
The FaibaGo Study - Long-Term Weight Reduction Via Low-Threshold Intervention
The main aim of this study is to assess the effect of a chewing gum containing galactooligosaccharides (GOS) on the body mass index (BMI), the metabolism and the oral and intestinal microbiomes in a population of overweight…
- Trial name
- NCT07036692
- Testing
- FibreGum
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Bern
Mastication, Disability
Orofacial Functions and Masticatory Function in Children With Different Types of Deterioration in Oral Health
This project aims at studying the evolution of masticatory function (food bolus granulometry, masticatory behavior, muscle activity and masticatory performance) during oral rehabilitation, in children with different types of oral…
- Conditions
- Mastication, Disability, Oral Stage, Child Development
- Trial name
- KIDYCROC (NCT05821140)
- Testing
- dental treatment for global oral rehabilitation, oral health check up
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Clermont-Ferrand
Molar-Incisor Hypomineralization (MIH), Masticatory Performance
Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization
This study aims to evaluate right-left chewing balance and masticatory function in children with Molar-Incisor Hypomineralization (MIH) before and after restorative treatment.
- Conditions
- Molar-Incisor Hypomineralization (MIH), Masticatory Performance, Occlusal Analysis, Chewing Function
- Trial name
- NCT07589179
- Testing
- Glass Hybrid Restorative Treatment
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Marmara University
Temporal Mandibular Joint Dysfunction
Effect of Rocabado Exercises With Strain Counter-Strain Technique on Muscles of Mastication for Pain, Jaw Function, and Quality of Life in Patients With Temporomandibular Joint Dysfunction
Temporomandibular joint dysfunction (TMD) is a common musculoskeletal disorder affecting the jaw joint and masticatory muscles, leading to pain, limited jaw function, and reduced quality of life.
- Trial name
- NCT07703059
- Testing
- Rocabado Exercise, Strain Counterstrain Technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Malocclusion
Comparison of Acupressure, Ibuprofen, and Chewing Gum for the Management of Post-Archwire Orthodontic Pain
The goal of this clinical trial is to find out which method works best to reduce pain after braces are adjusted for the first time (when the first archwire is placed).
- Trial name
- NCT07638644
- Testing
- Acupressure, Ibuprofen 400 mg (if necessary), Chewing Gum
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Bahria University
Mild Cognitive Impairment (MCI), Aging
Elderberry Functional Gum and Cognitive & Oral Health in Older Adults
Globally, the aging population is increasing rapidly, leading to a dramatic rise in the prevalence of Alzheimer's disease and other types of dementia.
- Conditions
- Mild Cognitive Impairment (MCI), Aging, Oral Microbiome
- Trial name
- NCT07054645
- Testing
- Elderberry Anthocyanin Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Completely Edentulous Patients
Stabilizing Mandibular Overdentures With a Single Implant Placed in the Canine Region of the Preferred Chewing Side
The investigators are evaluating the use of a single implant to stabilize complete dentures in the lower jaw, in the canine region of the preferred chewing side.
- Trial name
- c-SIMO (NCT06755034)
- Testing
- c-SIMO, m-SIMO
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Frauke Müller