Clinical trials: Mastication Disorder
Colorectal Cancer
Effectiveness of Gum Chewing on Ileus in Chinese Colorectal Patients Underwent Laparoscopic Colorectal Surgery
Gum chewing group will have less ileus and early resume of bowel motion than control group.
- Trial name
- NCT02419586
- Testing
- bubble gum
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Shum Nga Fan
Temporomandibular Joint Disorder
The Effect of Prolonged Sugar-Free Chewing Gum Mastication on Self-Reported Fatigue Levels and Changes of Static and Dynamic Surface Electromyography Parameters in Young Individuals With and Without Temporomandibular Joint Disorders.
This case-control study investigates fatigue induced by prolonged gum mastication in individuals with temporomandibular disorders (TMD).
- Trial name
- NCT07273123
- Testing
- Mastication of sugar-free chewing gum
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Milan
Colorectal Cancer (CRC)
Trial of Gum Chewing to Enhance the Restoration of Intestinal Motility in Colorectal Cancer Surgery
Surgery is one of the most frequent treatments of colorectal cancer. However, delayed restoration of intestinal motility is a common phenomenon in patients who undergo colorectal surgery, and may reduce comfort, prevent the early…
- Trial name
- NCT06860685
- Testing
- gum chewing
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Gum Chewing, Preoperative
Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function
The aim of this study was to investigate the effects of chewing gum before surgery on preoperative anxiety, postoperative gastrointestinal functions (time to first gas, time to first defecation, bowel sounds, abdominal…
- Conditions
- Gum Chewing, Preoperative, Anxiety, Postoperative Nausea and Vomiting
- Trial name
- NCT06603025
- Testing
- chewing gum
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Hepatocellular Carcinoma
Simo Decoction and Gum Chewing for Bowel Activity
Abdominal surgery, including hepatic resection for hepatocellular carcinoma (HCC), is inevitably followed by an episode of gastrointestinal hypomotility.
- Trial name
- SD/GC-HCC (NCT02438436)
- Testing
- simo decoction, gum chewing
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Plaque Induced Gingivitis
Comparative Effect of Chewing Sticks and Toothbrushing on Plaque Removal and Gingival Health
The purpose of the proposed study is to compare the effect of chewing sticks (Miswak) and the toothbrushes on plaque removal and gingival health.
- Trial name
- NCT01336179
- Testing
- Salvadora persica, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Taibah University
Anosmia, Parosmia
Multimodal Chewing Gum Flavour Training to Aid Flavour Perception Recovery - a Pilot Study.
Olfactory training is developed for people who have partly or completely lost their sense of smell (olfactory dysfunction). Participants expose themselves to odours twice daily for usually 12 weeks or longer.
- Conditions
- Anosmia, Parosmia, Phantosmia, Dysgeusia
- Trial name
- FITS (NCT07498062)
- Testing
- Flavour impairment training using chewing gum group (FIT), Olfactory training group (OT), Waiting list control group
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Oral and Esophageal Cancer, Metabolic Syndrome.
The Association Between Areca-nut Chewing Habit and Metabolic Syndrome
The purpose of this study is going to determine the odds ratio of metabolic syndrome (MS), the habit of areca nut chewing, antioxidant, and inflammatory status in oral and esophageal patients.
- Trial name
- NCT02175524
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taichung Veterans General Hospital
Type 2 Diabetes
Effect of Molar Replacement on Glycemic Control in Adults With Uncontrolled Type 2 Diabetes
Type 2 diabetes (T2D) is a major global health issue, affecting about 9.2% of adults in Europe. Although treatment begins with lifestyle changes and medications, up to half of patients fail to achieve adequate blood sugar…
- Trial name
- DIABETEETH (NCT07666529)
- Testing
- Replacement of one pair of molars
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mastication Disorder, Swallowing Disorder
Chewing, Swallowing and Orofacial Motricity in Severe Obese
Background: Obesity is considered an epidemic disease of great repercussion on the world and its prevalence has increased in recent decades.
- Conditions
- Mastication Disorder, Swallowing Disorder, Orofacial Dyskinesia
- Trial name
- NCT05516693
- Testing
- Myofacial muscle training protocol.
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centro Universitário de Anapolis
Plaque, Gingivitis
Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population
This study is to assess the safety and tolerability of single doses and multiple doses in reducing plaque and gingivitis when delivered in a chewing gum formulation.
- Trial name
- APCG (NCT01877421)
- Testing
- 2 mg KSL-W, 4 mg KSL-W, 6 mg KSL-W
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Acute Coronary Syndrome, STEMI
Chewing Ticagrelor Versus Prasugrel in ST-elevation Myocardial Infarction - A Platelet Reactivity Study
To examine the efficacy of chewing Ticagrelor versus Prasugrel in ST-elevation Myocardial Infarction (STEMI) patients on platelet reactivity.
- Trial name
- NCT03016611
- Testing
- Chewing Ticagrelor LD, Chewing Prasugrel LD
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Breast Cancer, Nausea and Vomiting
The Impact of Oral Cryotherapy and Chewing Gum Interventions
Chemotherapy-induced nausea and vomiting (CINV) and taste alterations continue to be among the most common and most severe side effects that women receiving adjuvant chemotherapy for breast cancer suffer.
- Conditions
- Breast Cancer, Nausea and Vomiting, Quality of Life, Chewing Gum
- Trial name
- NCT07145320
- Testing
- Oral Cryotherapy Group (Group 1), Chewing Gum Group (Group 2)
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Hacettepe University
Hyperphosphatemia in Chronic Kidney Disease
Efficacy of Phosphate Binding in Healthy Volunteers: Chewed Versus Crushed Lanthanum Carbonate
Patients with end-stage renal disease (ESRD) commonly have high concentrations of phosphorous, a mineral, in the blood (hyperphosphatemia). This is a result of their inability to excrete phosphorous by the kidneys.
- Trial name
- NCT00458289
- Testing
- Lanthanum carbonate (chewed vs. crushed)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Head and Neck Cancer, Radiation Therapy Complication
The Use of Chewing Gum for Xerostomia and Hyposalivation After Radiotherapy for Oral and Oropharyngeal Tumors
This study evaluates the possible benefits of a tasteless and sugar free chewing gum as a salivary stimulant for head and neck cancer patients treated with curative intended radiotherapy.
- Conditions
- Head and Neck Cancer, Radiation Therapy Complication, Xerostomia, Hyposalivation
- Trial name
- NCT03302676
- Testing
- Chewing gum
- Where
- Denmark
- Volunteers
- 109 people
- Sponsor
- Odense University Hospital
Microbial Colonization
Colonisation Efficacy of a Probiotic Chewing Gum.
To evaluate the colonization efficacy (the ability of a probiotic bacteria to remain in the mouth) delivered in a chewing gum format.
- Trial name
- NCT05624177
- Testing
- Streptococcus salivarius M18 probiotic 1 billion colony forming units chewing gum (chew 5 minutes), Streptococcus salivarius M18 probiotic 1 billion colony forming units chewing gum (chew 10 minutes)
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- BLIS Technologies Limited
Obesity, Overweight
Availability of Lipids in Almonds in Healthy Individuals
Evidence indicates that almond consumption is associated with multiple health benefits. However, nuts are commonly excluded from diets on the basis that their high energy content may induce weight gain.
- Trial name
- NCT00768417
- Testing
- 10 chews, 25 Chews, 40 Chews
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Dental Caries
Effect of a Sugar-Free Chewing Gum Containing Magnolia Bark Extract on Caries Lesions in Healthy Adult Volunteers
The effect of chewing gums containing MBE and xylitol on different variables related to caries and gingivitis in a sample of adult volunteers with a high risk for caries will be evaluated.
- Trial name
- NCT02310308
- Testing
- Chewing gum administration
- Where
- 2 sites in Italy
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Periodontal Disease
Study of Colonization of Strains L.Plantarum and L.Brevis in the Product AB-DENTALAC Chewing Gum
Study will follow a randomized, double-blind, placebo-controlled design with two groups in parallel,N of 40 patients in 6 weeks of follow up for the evaluation of two different posology models (daily consumption of probiotic gum…
- Trial name
- AB-GUM-2016 (NCT03540498)
- Testing
- AB-DENTALAC [Probiotics (study)]
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Drug-Resistant Epilepsy, ARX-Related Epilepsy
Occupational Therapy Approach in ARX-Related Epilepsy
This study evaluated the effects of medical ketogenic diet therapy combined with occupational therapy in children with ARX-related epilepsy. Twenty children were included.
- Trial name
- NCT07745608
- Testing
- Occupational Therapy, Medikal Ketogenic Diet Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Uskudar University