Clinical trials: Maternal
Physical Inactivity
Free Time For Wellness Pilot Effectiveness Trial
Physical inactivity is pervasive and prevalent in the United States, particularly among women of low socioeconomic position, and women with children.
- Trial name
- FT4W (NCT06474715)
- Testing
- Arms
- Where
- 3 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Columbia University
Maternal Death, Maternal Infections Affecting Fetus or Newborn
Azithromycin-Prevention in Labor Use Study (A-PLUS)
Maternal and neonatal infections are among the most frequent causes of maternal and neonatal deaths, and current antibiotic strategies have not been effective in preventing many of these deaths.
- Conditions
- Maternal Death, Maternal Infections Affecting Fetus or Newborn, Neonatal SEPSIS, Maternal Sepsis During Labor
- Trial name
- NCT03871491
- Testing
- Azithromycin
- Where
- 8 sites in Bangladesh, Democratic Republic of the Congo and 5 more
- Volunteers
- 58,747 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Parenting, Mother-child Relations
Collaborative Perinatal Mental Health and Parenting Support in Primary Care
Treating mothers' perinatal depressive and other mental health symptoms alone does not prevent impaired parenting quality and adverse infant outcomes.
- Trial name
- NCT02724774
- Testing
- Promoting First Relationships®
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- University of Washington
Breastfeeding, Bottle Feeding
Breast Versus Bottle Study
The objective of the proposed research is to conduct a within-subject experimental study that will assess the effect of feeding mode (breast- versus bottle-feeding) on the quality and outcome of infant feeding interactions.
- Trial name
- NCT03704051
- Testing
- Mode of Feeding (breastfeeding versus bottle-feeding)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Behavioral Health
Improving Future Thinking Among Mothers to Reduce Harsh Parenting and Improve Child Outcomes
Parents of children from impoverished communities are disproportionately more likely to engage in harsh physical discipline, which can lead to serious clinical outcomes, including suicidal ideation and attempts.
- Trial name
- NCT05229146
- Testing
- Episodic Future Thinking
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Maternal Behavior, Maternal Addiction
Oxytocin and Brain Responses in Maternal Addiction
A prior study by the principal investigator of this project identified dopamine- and oxytocin-related brain pathways that showed a diminished response when addicted mothers viewed the faces of their own vs.
- Trial name
- NCT02979093
- Testing
- Oxytocin, Functional MRI scanning
- Where
- 2 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Lane Strathearn, MBBS PhD
Labor, Induced, Cervical Ripening
Prehospital Cervical Ripening Before Induction and the Maternal Experience
This is a randomized study evaluating the impact of pre-hospital cervical ripening with a transcervical Foley balloon before labor induction in full-term pregnancies on the length of inpatient labor induction and maternal…
- Trial name
- "PRIME" (NCT01641601)
- Testing
- Outpatient transcervical Foley balloon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
HIV Infections
ARVs to Prevent Breastmilk HIV:Viral and Immune Responses
Identifying new approaches for preventing breastmilk transmission of HIV-1 is an important research priority. To this end, clinical trials are underway to evaluate the efficacy of HAART (zidovudine, lamivudine, nevirapine) during…
- Trial name
- NCT00167674
- Testing
- Combined short-course zidovudine/nevirapine, HAART
- Where
- Kenya
- Volunteers
- 58 people
- Sponsor
- University of Washington
Self-Efficacy for Decision Making, Apgar Score
Effectiveness of a Pender's Health Promotion Model-Based Diabetes Self-Management Program in Gestational Diabetes: A Clinical Trial
The aim was to evaluate the effect of a nursing education intervention based on Pender's SGM on gestational diabetes management and healthy lifestyle behaviors for pregnant women diagnosed with gestational diabetes.
- Conditions
- Self-Efficacy for Decision Making, Apgar Score, Behavior Change, Maternal and Neonatal Outcomes
- Trial name
- NCT07060963
- Testing
- Motivational interviews within the context of a health promotion-based diabetes self-management program
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- Ankara Yildirim Beyazıt University
Obesity, Sedentary
Effects of Obesity and Physical Inactivity on Pregnancy Outcomes
Regular maternal physical activity leads to the delivery of lighter, leaner infants. Higher birth weights and childhood obesity are both strong predictors for adult obesity, suggesting that the impact of maternal physical…
- Trial name
- NCT02039414
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Pregnancy, Child Development
Improving Maternal and Child Health Through Prenatal Fatty Acid Supplementation
The purpose of the study is to test whether nutritional supplementation during pregnancy is associated with 1) improved maternal health during pregnancy; 2) improved infant birth and neurodevelopmental outcomes, and 3) whether…
- Trial name
- NAPS (NCT02647723)
- Testing
- DHA, Sugar pill
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Fetal Monitoring
A Clinical Study for Validating the Equivalence of Bloomlife MFM-Pro to Clinical Standard-of-care for Performing Antepartum Fetal Monitoring
Bloomlife MFM-Pro is a non-invasive, wireless, external monitoring system used to measure fetal heart rate and maternal heart rate on pregnant women with a singleton pregnancy, starting from 32 weeks of gestation.
- Trial name
- NST (NCT04915131)
- Testing
- Bloomlife MFM-Pro
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Bloom Technologies
Maternal Health, Mental Health
Caring for Providers to Improve Patient Experience Study Phase 2 in Migori County
The activities described in this proposal are aimed at addressing health care provider stress and unconscious bias to improve quality of maternal health care, particularly related to the person-centered dimensions of care-i.e.
- Conditions
- Maternal Health, Mental Health, Healthcare Provider, Adverse Outcomes
- Trial name
- CPIPE2 (NCT05019131)
- Testing
- Training, Peer support and mentorship, Leadership engagement
- Where
- Kenya
- Volunteers
- 83 people
- Sponsor
- University of California, San Francisco
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hypovolemic Shock, Hemorrhage
Efficacy Study of the Non-Pneumatic Anti-Shock Garment (NASG) in Egypt
This study will test the efficacy of the NASG on women suffering from obstetric hemorrhage as compared to hemorrhaging women who do not receive the NASG.
- Trial name
- NCT00305253
- Testing
- Non-pneumatic Anti-shock Garment (NASG)
- Where
- 2 sites in Egypt
- Volunteers
- 990 people
- Sponsor
- University of California, San Francisco
ADHD, Parenting
Treating Parents With ADHD and Their Young Children Via Telehealth: A Hybrid Type I Effectiveness-Implementation Trial
This study will compare the effectiveness of combined parental stimulant medication and behavioral parent training (BPT) versus BPT alone on child ADHD-related impairment (primary outcome), child ADHD and externalizing symptoms…
- Trial name
- TPAC (NCT04240756)
- Testing
- Behavioral Parent Training, Extended release mixed amphetamine salts (MAS)
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- University of Maryland, College Park
Breastfeeding
Effects of Music Therapy on Breastfeeding Among Mothers of Premature Newborns
The purpose of this study is to evaluate the impact of music therapy on breastfeeding rates among mothers of premature newborns.
- Trial name
- NCT00930761
- Testing
- Music therapy
- Where
- Brazil
- Volunteers
- 101 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Postpartum Depression
Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum Depression
Postpartum depression (PPD) is undertreated and the consequences of this are substantial for women and children. Studies show that infant cry/fuss and sleep behavior are associated with PPD, and that parenting interventions can…
- Trial name
- NCT01379781
- Testing
- Behavioral Intervention for PPD
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Breastfeeding Duration
BOOST: Breastfeeding Onset and Onward With Support Tools
This behavioral intervention trial will test whether a standard care breastfeeding intervention from the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) program plus monthly financial incentives…
- Trial name
- NCT03964454
- Testing
- WIC support + home-based individual support + Breastfeeding Incentives (SC+BFI), WIC support + home-based individual support (SC)
- Where
- 2 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Philadelphia College of Osteopathic Medicine
Neonatal Abstinence Syndrome
Fetal and Infant Effects of Maternal Buprenorphine Treatment
This research will track the longitudinal neurobehavioral development of the buprenorphine-exposed fetus across gestation through 1 month of age in an effort to determine the safety of this medication for use during gestation…
- Trial name
- NCT01561079
- Testing
- Buprenorphine
- Where
- 2 sites in United States
- Volunteers
- 127 people
- Sponsor
- Johns Hopkins University