Clinical trials: Maternal Complication of Pregnancy
Prematurity
Effect of Auditory and Tactile-kinesthetic Stimulation on Preterm Neonates
The study was conducted at a level II special care nursery of the Moi Teaching \& Referral Hospital, an academic hospital in the Western region of Kenya.
- Trial name
- NCT04287322
- Testing
- Tactile-kinesthetic stimulation, Recorded maternal voice
- Where
- Kenya
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Moi University
Female Infertility
Intracytoplasmic Morphologically Selected Sperm Injection and Advanced Maternal Age
The objective of this study was to evaluate the advanced maternal age as a rationale for performing intracytoplasmic morphologically selected sperm injection (IMSI).
- Trial name
- IMSIAMA (NCT01620346)
- Testing
- Intracytoplasmic sperm injection (ICSI), Intracytoplasmic morphologically selected sperm injection
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Sapientiae Institute
Cervical Intraepithelial Neoplasia, Cervical Cancer
The Development of a "Mother/Child, Screen, Treat and Vaccinate Program" in Manchay and Iquitos, Peru
This project will use a community based participatory research orientation to develop a model for large scale "campaign" preventive healthcare interventions.
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Cervical Neoplasm, Cervical Dysplasia
- Trial name
- PERCAPS (NCT01338051)
- Testing
- Gardasil
- Where
- 2 sites in Peru
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Preventive Oncology International, Inc.
Newborn Infant, Bonding
The Effect of Lullaby During Bath Time on Mother-Infant Bonding, Postpartum Depression, and Parental Self-Efficacy in Infants
This randomized, single-blind controlled trial aims to evaluate the effects of maternal lullaby singing during infant bathing on mother-infant bonding, postpartum depressive symptoms, and perceived parenting self-efficacy in…
- Conditions
- Newborn Infant, Bonding, Self Efficacy, Postpartum Depression (PPD)
- Trial name
- NCT07370025
- Testing
- Maternal Lullaby Singing
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Preterm Labor
Maternal Serum Amyloid A Levels in Pregnancies Complicated With Preterm Labour.
The aim of the current study is to assess the accuracy of maternal serum amyloid A for prediction of preterm labor in women with threatened preterm labor.
- Trial name
- NCT03205020
- Testing
- serum amyloid a test
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- mona nematallah
Respiratory Distress Syndrome, Transient Tachypnea of Newborn
The Possible Effect Of Amniotic Fluid pH On Neonatal Morbidities In Maternal Inflammation/Infection Associated Pregnancies
Amniotic fluid (AF) pH can be affected by the maternal and/or fetal conditions such as PPROM, prematurity or fetal distress. It is known that fetal urine is the major content of AF since 20th gestational week.
- Conditions
- Respiratory Distress Syndrome, Transient Tachypnea of Newborn, Intrauterine Growth Retardation
- Trial name
- NCT02691559
- Testing
- Amniotic fluid analysis by blood gas device
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Premature
Oral Motor Intervention to Preterms by Their Mothers
Babies who have been discharged from the neonatal intensive care unit and have difficulty in oral feeding will be identified. Oral Motor Intervention (PIOMI) will be taught to the mothers of these babies and asked to practice.
- Trial name
- NCT06194513
- Testing
- Intervention 1: Twice a day for 1 week PIOMI, Intervention 2: Once a day for 2 weeks PIOMI
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Premature Birth, Mothers of Newborn Infants
Maternal Self-efficacy and Motor Development in Premature Infants: Clinical Trial Protocol
Mothers of premature newborns face special home care situations due to the conditions of their children after hospital discharge; This requires promoting the positive perception of maternal self-efficacy and thus achieving the…
- Trial name
- NCT06420635
- Testing
- Interdisciplinary intervention program on maternal self-efficacy and the motor development of premature children, Traditional kangaroo program
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Universidad de la Sabana
Trisomy 13, Trisomy 18
High Risk Multiple Gestation Study
The objectives of the clinical study are to demonstrate the accuracy of our proprietary algorithm method to determine the genetic health of the developing fetuses in a multiple gestation pregnancy from a maternal blood sample.
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
- Trial name
- NCT02278874
- Where
- 4 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Preterm Birth, Anxiety
Online Mother-Baby Yoga With Preterm Infants and Their Mothers
The purpose of this study is to examine the effects of internet-based mother-baby yoga on preterm infants and their mothers.
- Conditions
- Preterm Birth, Anxiety, Development, Infant
- Trial name
- NCT05147480
- Testing
- internet-based mother-baby yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Halic University
Preterm Birth
Effects of Mother's Voice and Heartbeat Sounds on Preterm Newborns
The purpose of this RCT is to learn more about how sounds that we experience in the womb can affect early development in premature infants.
- Trial name
- NCT01913288
- Testing
- Biological Maternal Sounds
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Brigham and Women's Hospital
Depression During Pregnancy, Pregnancy
Obstetric Exercise and Maternal Outcomes in Pregnancy
This randomized controlled trial will be conducted in the antenatal clinic and pregnancy school of a public hospital in eastern Türkiye.
- Conditions
- Depression During Pregnancy, Pregnancy, Pregnancy Complications
- Trial name
- BDI-PSI (NCT07170124)
- Testing
- Obstetric exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bingol University
Preeclampsia, Fullpairs
fullPIERS Model in the Prediction of Adverse Maternal Outcomes in Preeclampsia
Apredictive formula, fullPIERS (Pre-eclampsia Integrated Estimate of Risk Score), can be used to estimate the risk of suffering an adverse outcome using information obtained within 48 hours of admission with pre-eclampsia.
- Trial name
- Aprospective (NCT07316140)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Low Birth Weight Infants, Preterm Infants
Predictors and Outcomes of Kangaroo Mother Care: A Quasi-Experimental Study in Pakistan
This quasi-experimental study evaluated the impact of Kangaroo Mother Care (KMC) versus Conventional Care (CC) on the growth, developmental milestones, breastfeeding, vaccination, and mortality of low birth weight infants in…
- Trial name
- NCT06559020
- Testing
- Kangroo mother care
- Where
- Pakistan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Preterm Infant, Hypothermia Neonatal
Kangaroo Mother Care With Plastic Bag (Trials 2A & 2B)
The purpose of this study is to determine whether the combination of Kangaroo Mother Care (KMC) as continuously as possible together with the use of a plastic bag in combination with routine World Health Organization (WHO)…
- Trial name
- NCT03141723
- Testing
- KMC & WHO protocol (0-1 hour), KMC, WHO protocol & bag (0-1 hour), KMC & WHO protocol (1-24 hours)
- Where
- Zambia
- Volunteers
- 423 people
- Sponsor
- University of Alabama at Birmingham
Preeclampsia
Anti-Angiogenic Preeclampsia Milieu Impairs Infant Lung and Vascular Development
Pregnant mothers who develop high blood pressure and other vascular problems (preeclampsia) deliver babies with increased neonatal health problems, which include lung disease and vascular complications, later in life.
- Trial name
- NCT02639676
- Testing
- Diffusion Lung Capacity (DLCO), Vascular Challenge, Video Imaging, Specimen Collections
- Where
- United States
- Volunteers
- 292 people
- Sponsor
- Indiana University
Maternal Obesity, Obesity
The Developmental Origins of Obesity
Pregestational obesity (PGO, BMI ≥30) is a significant independent risk factor for the development of obesity in childhood and adolescence.
- Trial name
- OMEGA-Stem (NCT06981676)
- Testing
- DHA and EPA
- Where
- Chile
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
HIV Infections, Pregnancy
A Study of Nevirapine to Prevent HIV Transmission From Mothers to Their Infants
The purpose of this study is to see if giving the anti-HIV drug nevirapine (NVP) to HIV-positive pregnant women and their infants can help reduce the chance that a mother will give HIV to her baby during delivery.
- Trial name
- NCT00001135
- Testing
- Nevirapine
- Where
- 20 sites in United States, Puerto Rico
- Volunteers
- 2,009 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gestational Diabetes Mellitus, Pregnancy Outcome
GDM and Its Consequences in Mothers and Offsprings
Gestational diabetes mellitus (GDM) is one of the most common disorders which occured during pregnancy. GDM is not only associated with short-term maternal and fetal adverse outcomes, but also related to a wide range of long-term…
- Conditions
- Gestational Diabetes Mellitus, Pregnancy Outcome, Neurodevelopment, Immune Development
- Trial name
- GDMCMO (NCT04529889)
- Where
- China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Gestational Diabetes, Oxidative Stress
Prevention of Maternal and Fetal Metabolic Complications With Diet and Nutraceutical Supplementation in Pregnant Women Affected by Gestational Diabetes: a Randomized, Double-blind Placebo Controlled Trial.
Our trial aims to assess the effect of nutraceutical supplements (omega-3 fatty acids, anthocyanins and alpha-cyclodextrins) in patients affected by gestational diabetes.
- Trial name
- PREDIP2 (NCT05393843)
- Testing
- omega-3 fatty acids, anthocyanins and alpha-cyclodextrins, diet
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico