Clinical trials: Maternal Death
COVID-19, COVID-19 Pneumonia
Effect of Covid 19 Infection on Fetomaternal Outcome
The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was discovered for the first time in December 2019 in Wuhan (China) and the disease it causes is called coronavirus disease 2019…
- Conditions
- COVID-19, COVID-19 Pneumonia, Fetal Growth Retardation
- Trial name
- NCT05160649
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University
Vaginal Infection
Impact of Maternity Napkins on the Incidence of Vaginal Infections in the Post-partum Period
This randomized controlled trial will compare the incidence of vaginal infections in the post-partum period in women using sanitary napkins, with women using their current methods of managing lochia.
- Trial name
- NCT05806879
- Testing
- Maternity Napkin
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pregnancy, Preterm Labor
Biomarkers in Obstetrical Complications
Objective: To study the natural history of normal pregnancy and the most frequent pregnancy complications responsible for the excessive rate of perinatal morbidity and mortality, in order to develop models to predict the…
- Conditions
- Pregnancy, Preterm Labor, Maternal Fetal Factors, Preterm Birth
- Trial name
- NCT03480139
- Where
- United States
- Volunteers
- 746 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Maternal Death, Maternal Behavior
Effectiveness of Health Education Provided to Couples on Utilization of Maternity Waiting Homes in Rural Ethiopia
Maternity waiting homes (MWHs) were identified as a solution to improve pregnancy outcomes by bringing women living in geographically isolated areas closer to a healthcare facility.
- Trial name
- NCT05015023
- Testing
- Behavioral intervention
- Where
- Ethiopia
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Jimma University
Infant Mortality, Infant Death
Today Not Tomorrow Pregnancy and Infant Support Program (TNT- PISP)
This pilot project aims to implement and investigate the feasibility and acceptability of a unique community based prenatal care and support model for African American women and infants in Dane County.
- Conditions
- Infant Mortality, Infant Death, Racial Bias, Prenatal Stress
- Trial name
- NCT04100577
- Testing
- Today Not Tomorrrow Pregnancy and Infant Support Program
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Postpartum Care
Focused-PPC: An Integrated Postpartum Care, Education, and Support Model for Women in Ghana
The purpose of this project is to test and evaluate an innovative postpartum care, education, and support model that integrates recommended clinical care, education, and support for women in a group setting. Aim 1.
- Trial name
- Focused-PPC (NCT05280951)
- Testing
- Focused-PPC Care, Usual Care
- Where
- 4 sites in Ghana
- Volunteers
- 192 people
- Sponsor
- University of Notre Dame
Neonatal Death, Maternal Death
Safe Motherhood Promotion and Newborn Survival
Primary objective of the study is to measure the impact of a comprehensive package of interventions introduced by the Safe Motherhood Promotion and Newborn Survival project on neonatal mortality in three Upazila of Chandpur…
- Trial name
- SMPNS (NCT03032276)
- Testing
- Safe motherhood and newborn health promotion package
- Volunteers
- 50,400 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Abortion Complication
Abortion-related Morbidity and Mortality in Conflict-affected and Fragile Settings Study
To describe and estimate the burden of abortion-related complications, particularly near-miss complications and deaths, and their associated factors among women presenting for abortion-related complications in health facilities…
- Trial name
- AMoCo (NCT04331847)
- Where
- 3 sites in Central African Republic, Democratic Republic of the Congo and 1 more
- Volunteers
- 2,500 people
- Sponsor
- Epicentre
Maternal Death, Cardiac Arrest
Assessing a New Proforma for Maternal Cardiac Arrest
During the Multidisciplinary Obstetric and Midwifery Simulation (MOMS) course, groups of delegates manage simulated clinical emergencies, whilst the remaining delegates observe the scenario via a video link.
- Conditions
- Maternal Death, Cardiac Arrest, Heart Arrest
- Trial name
- NCT04260386
- Testing
- Non-Interventional
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Prenatal Care
Group Antenatal Care: The Power of Peers for Increasing Skilled Birth Attendance in Achham, Nepal
In rural Nepal, the major drivers of underutilization of skilled birth attendance are poverty, poor social support and inadequate birth planning.
- Trial name
- NCT02330887
- Testing
- Group Antenatal Care, Individual Antenatal Care
- Where
- Nepal
- Volunteers
- 2,184 people, healthy volunteers welcome
- Sponsor
- Possible
Neonatal Mortality, Maternal Mortality
Impact of New Tools of Simulation-enhanced Peer Learning on Neonatal and Maternal Mortality
In the vast majority of developing nations, frontline birth attendants are often the only care providers responsible for newborn care including newborn resuscitation, thermal care, feeding and administration of medications.
- Trial name
- Sim-II (NCT04904380)
- Testing
- Active peer learning
- Volunteers
- 3,456 people
- Sponsor
- Mbarara University of Science and Technology
Maternal Mortality, Maternal Morbidity
An Implementation Study of Interventions to Promote Safe Motherhood in Jimma Zone Ethiopia
Ethiopia has one of the highest rates of maternal mortality among all countries in Africa and indeed worldwide, with a maternal mortality ratio of 676 per 100,000 live births in 2011 (UNFPA, 2012).
- Trial name
- NCT03299491
- Testing
- MWA intervention, IEC intervention
- Volunteers
- 3,784 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Contraception Behavior, Contraceptive Usage
A Cluster-RCT to Increase the Uptake of LARCs Among Adolescent Females and Young Women in Cameroon.
The study investigators propose to test various supply-side approaches to increase the numbers of both SARCs (short-acting reversible contraceptives, i.e.
- Conditions
- Contraception Behavior, Contraceptive Usage, Contraceptive Method Switching, Contraception
- Trial name
- NCT03725358
- Testing
- Training, App, Control
- Sponsor
- World Bank
Hypoxic Brain Injury, Maternal Death
High Flow Nasal Cannula to Prevent Deoxygenation During Induction of General Anesthesia in Cesarean Section
Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) using high flow oxygen therapy for preoxygenation and oxygen supplementation during apnoea has shown promising results
- Trial name
- NCT04438798
- Testing
- F Group, H Group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Maternal Death, Infant Death
Effects of a Health Workforce Capacity Building and Quality Improvement Intervention in Kinshasa
The aim of the study is to evaluate a health workforce capacity building and quality improvement intervention focused on integrated day-of-birth and post-pregnancy care at 16 hospitals in Kinshasa, Democratic Republic of Congo.
- Conditions
- Maternal Death, Infant Death, Stillbirth
- Trial name
- NCT03363308
- Testing
- training for health care workers supplmented by QI teams
- Where
- Democratic Republic of the Congo
- Volunteers
- 250 people
- Sponsor
- Jhpiego
Maternal Death, Newborn Death
Replicating MamaToto in Rural Tanzania
This study aimed to adapt and implement a district-led, policy-based, low cost Maternal and Newborn Health (MNH) intervention package using the MamaToto process, proven successful in Uganda, in rural Tanzania.
- Trial name
- NCT02506413
- Testing
- MamaToto Package
- Where
- Tanzania
- Volunteers
- 8,323 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Maternal Death During Childbirth
Critical Delays in Cardiopulmonary Resuscitation During Simulated Obstetric Crisis: a Prospective Observational Study.
Maternal cardiac arrest is underreported and continues to occur at rate of 1:20,000 pregnancies. Despite being predominantly younger patients, survival rates among pregnant women are poor with one case series reporting a survival…
- Trial name
- NCT04050631
- Testing
- maternal arrest simulation on L&D floor
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Maternal Mortality, Cesarean Section
The ASOS-2 Trial Maternal Mortality Sub-study
This sub-study is a mixed-methods analysis of a prospective case-series of maternal deaths within the African Surgical OutcomeS-2 trial cohort.
- Conditions
- Maternal Mortality, Cesarean Section, Africa
- Trial name
- NCT04029207
- Testing
- Cesarean section
- Where
- South Africa
- Volunteers
- 100 people
- Sponsor
- University of Cape Town
Maternal Death
Critically-Ill Women Admitted to an Obstetric High Dependency Unit in a Resource-Limited Setting
Sierra Leone faces the highest maternal mortality ratio in the world. Despite this extreme burden, the potential roles of obstetric critical care and high dependency units (HDUs) in this and other resource-limited settings remain…
- Trial name
- NCT04121234
- Testing
- Exposure: " being admitted to HDU with a red code to OEWS"
- Where
- Sierra Leone
- Volunteers
- 523 people
- Sponsor
- Doctors with Africa - CUAMM
Obstetric Labor Complications, Stillbirth
The PartoMa Project: For Improving Monitoring, Action and Triage During Labour
OVERALL OBJECTIVE In an East African referral hospital, to develop and analyze the effect of locally agreed and achievable guidelines and a continual in-house training program for strengthening partogram-based…
- Conditions
- Obstetric Labor Complications, Stillbirth, Maternal Death
- Trial name
- PartoMa (NCT02318420)
- Testing
- The PartoMa intervention
- Where
- Tanzania
- Volunteers
- 3,087 people
- Sponsor
- Ib Christian Bygbjerg