Clinical trials: Maternal Obesity
Pregnancy Related, Adolescent Obesity
#BabyLetsMove Physical Activity Feasibility Trial
Black adolescents who are pregnant represent a high-risk and understudied perinatal population in health research. Adolescent pregnancy (<20 years) is disproportionately prevalent among Blacks compared with Whites and is a…
- Conditions
- Pregnancy Related, Adolescent Obesity, Behavior, Health, Behavior, Sedentary
- Trial name
- NCT04628065
- Testing
- #BabyLetsMove
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
HIV, Obesity
Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir
A total of 1900 pregnant women in the 1st trimester and their children will be enrolled and followed for two years (ORCHID study main cohort).
- Conditions
- HIV, Obesity, Obesity, Infant, Maternal Obesity During Childbirth
- Trial name
- ORCHID (NCT04991402)
- Testing
- Dolutegravir-based antiretroviral therapy
- Where
- 2 sites in South Africa
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Columbia University
Maternal Behavior, Body Weight
Maternal and Infant Growth Study
Rapid growth early in infancy is a risk factor for obesity and cardiovascular disease later in the lifespan. Evidence is limited, but both pre- and postnatal factors are associated with early rapid growth, and include high…
- Conditions
- Maternal Behavior, Body Weight, Infant Behavior
- Trial name
- RIF (NCT02893319)
- Testing
- Feeding and growth differences, 5oz vs 8oz bottle
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Leann Birch
Obesity
The Effects of Natural Sugars in Breast Milk on Healthy Infant Growth and Development
This study will investigate the effects of breastfeeding and breastmilk composition on infant gut microbiome development as well as obesity and cognitive outcomes.
- Trial name
- NCT04434027
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity During Pregnancy in Clinical Practice
The Impact of Maternal Obesity on Pregnancy Outcomes in El-Minia Locality
A study will carried out over a period of one year , all obese pregnant women as diagnosed with BMI at the time of 1st ANC visit and before labor ,observation of events during both intra-partum \&postpartum periods it will be…
- Trial name
- NCT02719873
- Testing
- The impact of maternal obesity on pregnancy outcomes
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Minia University
Maternal Obesity
Evaluating Pyrroloquinoline Quinone (PQQ) for Improving Obese Pregnancy Outcomes
Maternal obesity (MO) affects 1 in 5 women and is strongly linked to increased birth weight, childhood/adolescent obesity, life-long metabolic and inflammatory disorders, and childhood neuropsychiatric disorders.
- Trial name
- EPyQ (NCT06245083)
- Testing
- Pyrroloquinoline quinone (PQQ)
- Where
- United States
- Sponsor
- University of Oklahoma
Preterm Birth, Neurodevelopmental Disorders
Guangzhou Preterm and Term Birth Cohort Study
The Guangzhou Preterm-Term Birth Cohort (GPTBC) is a prospective observational study of how early-life nutrition, environmental exposures, and family factors relate to the health and development of preterm and term infants and…
- Conditions
- Preterm Birth, Neurodevelopmental Disorders, Overweight, Obesity
- Trial name
- GPTBC (NCT07756177)
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Pregnancy Complications, Maternal Obesity
Gasdermin-D and Pannexin-1 in Pregnancy
One -third of fertile women around the world are overweight or obese. This means increasing risk for both the mother and the child.
- Trial name
- NCT05475951
- Testing
- Biomarker measurement of pannexin-1 and gasdermin-D
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Obesity
The Sweet PEA Study: Effects of Diet During Pregnancy on Infant Growth and Development.
The purpose of the Sweet PEA Study is to determine whether diet during pregnancy has an effect on infant's growth, body composition, and brain development.
- Trial name
- NCT04674033
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Labor Long
The Use of Peanut Ball in Labor in Obese Women
The purpose of this study is to assess the efficacy of peanut ball use on labor process and maternal, neonatal outcomes in obese pregnant women.
- Trial name
- NCT05276947
- Testing
- position with peanut ball
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Mental Health, Child Wellbeing
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes.
- Conditions
- Mental Health, Child Wellbeing, Infant Health, Child Health
- Trial name
- GenV (NCT05394363)
- Where
- Australia
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Obesity, Infertility, Female
Fit-for-Fertility Multicenter Randomized Controlled Trial
Infertility affects approximately 10-15% of couples and one of its important modifiable risk factor is obesity, which affects 19% of Canadian women of reproductive age.
- Trial name
- FFF (NCT03908099)
- Testing
- Fit-For-Fertility program, Standard of care
- Where
- 5 sites in Canada
- Volunteers
- 408 people
- Sponsor
- Université de Sherbrooke
Healthy
Maternal Obesity and Offspring Neurodevelopment
Our goals are to characterize the effects of maternal obesity during pregnancy on infant brain development, reveal the neurodevelopmental consequences, and identify possible mechanisms causing these effects.
- Trial name
- Moon (NCT04274140)
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Obesity, Hyperglycemia
Pregnancy and EARly Lifestyle Improvement Study
The investigators propose to conduct a randomized controlled trial in 200 overweight/obese pregnant women and their offspring. The prenatal intervention will emphasize improving diet and physical activity.
- Trial name
- PEARLS (NCT01771133)
- Testing
- Lifestyle intervention group
- Where
- Puerto Rico
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico