Clinical trials: Maxillofacial Abnormalities
Cleft Lip, Cleft Palate
Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)
The Allied Cleft \& Craniofacial Quality-Improvement and Research Network (ACCQUIREnet) is a group of multidisciplinary cleft teams that have implemented a system for prospective collection of outcomes data, based on the ICHOM…
- Conditions
- Cleft Lip, Cleft Palate, Cleft Lip and Palate
- Trial name
- ACCQUIREnet (NCT02702869)
- Testing
- cleft lip repair, cleft palate repair, oronasal fistula repair
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,000 people
- Sponsor
- Duke University
Class II Malocclusion, Mandibular Deficiency
Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II
Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is…
- Trial name
- NCT07340242
- Testing
- MARA appliance, fixed twin block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Cleft Palate Children, Cleft Alveolar Ridge
Alveolar Cleft Repair Using Osteoinductive Ceramics
In this study, patients with unilateral cleft lip and palate are enrolled in a multicenter stepped wedge randomized trial ithat compares alveolar cleft closure using autologous bone harvested form the mandibular symphysis with an…
- Conditions
- Cleft Palate Children, Cleft Alveolar Ridge, Cleft Lip and Palate
- Trial name
- ACROSTIC (NCT05331456)
- Testing
- Unilateral alveolar cleft repair
- Where
- 4 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- UMC Utrecht
Orthognathic Surgery, Maxillofacial Abnormalities
Study Evaluating the Performance and Safety of Global D Implants Indicated for Orthognathic Surgery
This study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety of the Global D implants (ORTRAUTEK® and MINITEK®) used for…
- Conditions
- Orthognathic Surgery, Maxillofacial Abnormalities, Maxilla Fracture
- Trial name
- CMF-ORTHO (NCT05271383)
- Testing
- Orthognathic surgery using Global D's implants.
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Global D
Apnea, Airway Obstruction, Nasal
Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion
Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least.
- Conditions
- Apnea, Airway Obstruction, Nasal, Mandible Small, Maxillary Hypoplasia
- Trial name
- NCT04190953
- Testing
- Twin block then Hyrax, Hyrax then Twin block
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cleft Palate, Plasma Rich in Growth Factors
Role of Plasma Rich Growth Factor in Repair Primary Cleft Palate
Does the plasma-rich growth factor (PRGF) with primary cleft palate repair accelerate wound healing and prevent post-operative oronasal fistula occurrence?
- Trial name
- PRGF (NCT06889181)
- Testing
- Plasma Rich in Growth Factors (PRGF)
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Palate Children
Effect of Infant Sign Training on Speech-language Development
Children born with a cleft lip and palate (CLP) are known to be at risk for speech-language disorders that impact academic and social emotional growth.
- Trial name
- NCT06143254
- Testing
- Infant sign training, Verbal training
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Dentofacial Deformities, Analgesia
Effects of Local Ketamine in Orthognathic Procedures
Orthognathic surgery is performed to correct congenital, developmental, or trauma-related skeletal deformities of the maxilla and mandible.
- Conditions
- Dentofacial Deformities, Analgesia, Vomiting, Postoperative, Nausea, Postoperative
- Trial name
- NCT07066306
- Testing
- Ketamine, Articaine Hydrochloride + Epinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Heart Failure With Preserved Ejection Fraction, Prognathism
Effect of Bilirubin on Prognosis in Heart Failure With Preserved Ejection Fraction
Factors influencing the prognosis of patients with heart failure with preserved ejection fraction (HFpEF) have been extensively studied.
- Trial name
- NCT06379152
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chongqing Medical University
Dentofacial Abnormalities, Dentofacial Deformities
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but…
- Conditions
- Dentofacial Abnormalities, Dentofacial Deformities, Dentofacial Anomalies, Including Malocclusion, Malocclusion
- Trial name
- OSP (NCT04117360)
- Testing
- Orthognathic surgery and Orthodontics
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of North Carolina, Chapel Hill
Mandibular Fractures, Mandible Fracture
Facial iD Customized Mandible Reconstruction Plates
A retrospective post market follow up to confirm the safety and performance of Stryker's Customized Plates for Mandibular Reconstruction.
- Conditions
- Mandibular Fractures, Mandible Fracture, Mandible; Deformity, MANDIBLE
- Trial name
- NCT07245758
- Testing
- Mandibular reconstruction
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stryker Craniomaxillofacial
Implant Site Reaction, Maxillary Deficiency
Radiographic Assessment of Bone Gain Following Sinus Lifting With Simultaneous Implant Placement Using Crestal Approach With Membrane Control Technique for Bone Augmentation of Atrophied Maxillary Posterior Ridge
This study aims to evaluate the quantity and quality of the native and the newly bone around dental implants that's simultaneously installed with sinus lifting
- Trial name
- NCT06446687
- Testing
- Dental implant with sinus lifting.
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maxillofacial Abnormalities
Impact of Maxillomandibular Deformities on Individuals' Nutritional Status
This cross-sectional study explores the influence of various types of maxillomandibular deformities on the nutritional status of individuals.
- Trial name
- NCT05936476
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cleft Palate
Optic Nerve Sheath Diameter Measurement in Cleft Palate Repair
The aim of this study is to evaluate the effect of the Boyle-Davis mouth opener, which is routinely used in cleft palate surgery, on intracranial pressure by USG-guided optic nerve sheath diameter measurement, which is a…
- Trial name
- NCT04718558
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karadeniz Technical University
Three Dimensional, Dento-Skeletal
Three Dimensional Evaluation of Dento-Skeletal Effects of Leaf Self Expander in Cleft Lip and Palate Patients
This study aims to evaluate the dento-alveolar changes after maxillary expansion in cleft lip and palate patients by Leaf Self Expander, as compared to conventional Rapid Maxillary Expander using digital cast analysis and…
- Conditions
- Three Dimensional, Dento-Skeletal, Leaf Self Expander, Cleft Lip
- Trial name
- NCT07384338
- Testing
- Rapid maxillary expansion, Leaf Self Expander
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Cleft Palate
Relational Development in Children With Cleft Lips and Palates: Influence of the Waiting Period Prior to the First Surgical Intervention and the Parents' Psychological Perception of the Abnormality
The treatment of patients suffering from cleft lip(s) with or without a cleft palate (CL/P) is multidisciplinary. The careful consideration of concerned families during the repetitive appointments required by these treatments…
- Trial name
- NCT00993993
- Where
- 6 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Maxillary Deficiency
Comparative Results of Maxillary Deficiency Treatment by Fixed Tongue Appliance and Fixed Facemask in Growing Patients
A new fixed appliance will be used to transfer the tongue force during its physiological activity to advance the nasomaxillary complex; this method will be compared with the traditional method which uses a facemask with a fixed…
- Trial name
- NCT00916084
- Testing
- Fixed Tongue Appliance, Fixed Face Mask
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Posterior Crossbite, Maxilla; Hypoplasia
Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite.
Design: Two-arm parallel randomized clinical trial in mixed dentition (6-12 years). Arms: (1) 9 mm, 900 g leaf expander; (2) 9 mm Hyrax expander.
- Trial name
- NCT07301918
- Testing
- The Leaf expander, Hyrax expander
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cleft Palate
A Single Bolus of Dexmedetomidine Versus Normal Saline in Postoperative Agitation
The hypothesis of this study is to investigate and compare the efficacy between the administrations of single intravenous (IV) dose of dexmedetomidine versus normal saline in preventing immediate postoperative agitation in…
- Trial name
- NCT04928391
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Head and Neck Neoplasm, Cleft Palate
Characteristics of a Maxillofacial Prosthesis Consultation Within Assistance Publique - Hopitaux de Paris
Patients treated with Maxillofacial Prosthesis have loss of maxillary and/or mandibular substances. Few data are available on quality of life of these patients and its association with some of their socio-demographic, medical and…
- Conditions
- Head and Neck Neoplasm, Cleft Palate, Cleft Lip
- Trial name
- PEC-PMF (NCT04277273)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris