Clinical trials: Maxillofacial Deformity
Cleft Lip, Cleft Palate
Follow Ups of Parents With Infants With Cleft Lip and Palate
In Norway, 100-120 children are born with CLP (1.9 per 1,000 live births) each year. Parents of infants with CLP need information and support, especially with feeding immediately after birth. These needs are often not met.
- Trial name
- NCT02415361
- Testing
- Cleft lip and palate
- Where
- Norway
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Maxillary Deficiency
Comparative Results of Maxillary Deficiency Treatment by Tongue Plate and Facemask in Growing Patients
A new appliance will be used to transfer the tongue force during its physiological activity to advance the nasomaxillary complex; this method will be compared with the traditional method which uses a Facemask appliance.
- Trial name
- NCT00519415
- Testing
- Tongue plate, Facemask
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Cleft Palate, Tube Disorders Eustachian
Exercises for Improving Soft Palate and Eustachian Tube Function in Children With Ear Tubes With or Without Cleft Palate
Elevation of the soft palate (the soft part of the roof of the mouth) during swallowing helps the Eustachian tube to open and keep the ear healthy.
- Conditions
- Cleft Palate, Tube Disorders Eustachian, Velopharyngeal Incompetence Due to Cleft Palate, Velopharyngeal Insufficiency
- Trial name
- NCT03868891
- Testing
- EMST150
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Noel Jabbour
Retrognathia, Malocclusion, Angle Class II
Maxillary Patient Specific Implants in Bimaxillary Orthognathic Surgery
Orthognathic surgery is a type of jaw surgery where a surgeon cuts the bones of the upper and lower jaw and places them better. There are two ways they can put the bones in the correct place and keep them in place after the…
- Trial name
- NCT06297109
- Testing
- Patient-specific implants, Conventional mini-plates
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Cleft Palate
Nebulized Bupivacaine Analgesia for Cleft Palate Repair
In this study we introduce a potent local anesthetic; bupivacaine 0.5% in 0.5 mg/kg dose by nebulization as a preemptive analgesia to compare efficacy and safety in children with cleft palate repair.
- Trial name
- NCT04928352
- Testing
- Bupivacaine Hydrochloride, 0.9% saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cleft Lip, Cleft Palate
Characterization of Cleft Lip and Palate Conditions in Guatemala
The purpose of this study is to compare types of and risk factors for cleft lip and palate in a Guatemalan population to a United States population.
- Conditions
- Cleft Lip, Cleft Palate, Cleft Lip and Palate
- Trial name
- NCT04725370
- Testing
- NA - survey instrument
- Where
- United States
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Cleft Palate, Orofacial Cleft
Neural Network to Calculate Morphology of the Cleft Palate to Reduce Cleft Lip and Palate Treatment Burden.
This study is to develop a neural network to compute palatal three dimensional (3D) geometry by using routinely taken intraoral/palatal photographs and palatal casts of infants with cleft lip and palate deformity for reducing…
- Trial name
- NCT04342234
- Testing
- data collection of palatal casts and palatal images of cleft patients routinely treated at the institution
- Where
- Switzerland
- Volunteers
- 450 people
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Pain
Peripheral Nerve Block Techniques During Cleft Palate
Regional blocks are commonly used in pediatric anesthesia to achieve adequate postoperative analgesia. Suprazygomatic Maxillary nerve block (SMN) and Greater Palatine nerve block (GPN) are regional blocks described for use during…
- Trial name
- NCT04467463
- Testing
- peripheral nerve block by 0.25% levobupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Health-related Quality of Life, Dentofacial Deformities
Cross Cultural Adaptation and Validation of Orthognathic Quality of Life Questionnaire (OQLQ)
The aim of this study was to develop a Spanish version of the Orthognathic Quality of Life Questionnaire (OQLQ) that is conceptually equivalent to the original questionnaire, as well as acceptable, reliable, valid, and responsive…
- Trial name
- NCT04863170
- Testing
- orthognathic surgery
- Where
- Chile
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hospital Carlos Van Buren
Orthodontic Appliance Complication, Dental Malocclusion
Changes in the Upper Airway Volume After Rapid Maxillary Expansion in Adults Using Pure Skeletal Anchorage
The objective of this study is to evaluate the effect of bone-anchored rapid maxillary expansion (RME) in the volume of the right maxillary sinus, left maxillary sinus and nasal and maxillary sinus airway complex, through bone…
- Conditions
- Orthodontic Appliance Complication, Dental Malocclusion, Bone Anchored Rapid Maxillary Expansion, Maxillary Hypoplasia
- Trial name
- NCT05831722
- Testing
- Rapid Maxillary Expansion
- Where
- 3 sites in Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Cleft Palate Children, Laser
Low Level Laser in Isolated Cleft Palate Repair Versus Surgical Correction Without LLL in Healing Process
Does the use of low level laser (LLL) after surgical correction of cleft palate improve healing and decrease incidence of oronasal fistula?
- Trial name
- NCT03688737
- Testing
- low level laser
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infants, Difficult Airway
Oxygen Insuflation and ArterialDesaturation During Tracheal Intubation in Children
Infants (0-1 yr.) with anticipated difficult airways will be enrolled in the study. Specifically, we will include infants with cleft palate, Pierre Robin, Treacher Collins, trisomy 21, or similar congenital malformations.
- Trial name
- NCT01664234
- Testing
- laryngoscopy with oxygen, laryngoscopy without oxygen
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University of Vienna
Craniofacial Abnormalities, Mandibular Hypoplasia
Dexmedetomidine Versus Sevoflurane in Children With Anticipated Difficult Intubation
difficult problem in the paediatric age group because of their small mouth opening and un-cooperativeness.Currently used methods of sedation for fibreoptic intubation such as benzodiazepines, propofol or opioids may cause…
- Trial name
- NCT04426552
- Testing
- dexmedetomidine, sevoflurane
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Cleft Palate
Suprazygomatic Block in Cleft Palate Surgery in Children
Cleft palate (CP) is a common congenital malformation, with an incidence ranging from 0.1 to 1.1 per 1000 births depending on the population group (liau et al, 2010).
- Trial name
- NCT03412474
- Testing
- Bupivacaine, Dexmedetomidine, paracetamol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Maxillary Deficiency, Horizontal Alveolar Bone Defect
Osseodensification Versus Alveolar Ridge Splitting
Evaluation of clinical and radiological outcomes of the alveolar ridge splitting technique versus Osseodensification burs in atrophic maxillary alveolar ridges in horizontal dimension.
- Trial name
- OD Vs ARS (NCT06728202)
- Testing
- A Horizontal Ridge Augmentation in Atrophic Maxillary Ridge
- Volunteers
- 46 people
- Sponsor
- Fayoum University
Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate
Expiratory Muscle Strength Training for Hypernasal Speech in Children
When the soft palate does not move enough because of a cleft palate or for unknown reasons, this can lead to a speech difference called velopharyngeal insufficiency.
- Conditions
- Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate, Inadequate Velopharyngeal Closure, Palatopharyngeal Incompetence
- Trial name
- NCT05492266
- Testing
- Expiratory Muscle Strength Training, Maintenance Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Noel Jabbour
Cleft Palate
Effect of Furlow Palatoplasty With Buccal Myomucosal Flap on the Speech Development
About 20 patient will be collected according to the eligibility criteria and grouped into Group I : 10 patients were treated with furlow with buccinators flap Group II : 10 patients were treated with 2 flap palatoplasty All…
- Trial name
- NCT06856330
- Testing
- furlow with buccal myomucosal flap, two flap palatoplasty
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Fayoum University
Expansion of Maxillary Arch, Maxillary Hypoplasia
Dentoskeletal Changes Expansion Using Invisalign Versus Conventional Expander
Cbct evaluation of dentoskeletal changes after expansion using Invisalign versus conventional expander
- Trial name
- NCT05899530
- Testing
- Invisalign, Conventional expander
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cleft Lip and Cleft Palate
Aesthetic and Functional Self-Assessment Following Rhinoseptoplasty in Patients With Unilateral Cleft Lip and Palate
Secondary rhino-septoplasty in unilateral cleft lip and palate is the treatment of choice for the correction of aesthetic deformities and the functional impact on ventilation nasal. It remains a difficult treatment.
- Trial name
- RHINOFENTE (NCT07048418)
- Testing
- Mailing and completing CLEFT-Q and NOSE questionnaires
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Maxillary Hypoplasia
Maxillary Segment Tipping During Transpalatal Distraction
The investigator proposes a multi-centre study to investigate tipping of teeth, bringing into consideration the height of the osteotomy line and the height and placement of the transpalatal distractor as possible factors.
- Trial name
- NCT04041388
- Testing
- Conebeam CT
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitair Ziekenhuis Brussel