Clinical trials: Maxillofacial Surgery
Wound Heal
Comparison of Simple and Continuous Suture Techniques in Oral Surgery
The study aims to compare two different suture techniques regarding wound healing. In this research, which is designed as a prospective study, a comparison of simple and locked continuous suture techniques will be done.
- Trial name
- NCT06020157
- Testing
- Simple Suture Technique, Continuous Suture Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cleft Lip, Cleft Palate
Cleft Palate Surgery and Speech Development
Compare the outcome of two primary surgeries techniques (von Langenbeck and Furlow double z-plasty) performed on children with cleft lip/palate to determine if one results in significantly better velopharyngeal competency for…
- Trial name
- NCT00004639
- Testing
- Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair
- Where
- 2 sites in United States, Brazil
- Volunteers
- 475 people
- Sponsor
- University of Florida
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork
Surgery, Oral, Pain, Postoperative
A Comparison of the Effectiveness and Safety of ULTRACET® (Tramadol Hydrochloride/Acetaminophen) Versus ULTRAM® (Tramadol Hydrochloride) Versus Placebo in Patients With Pain After Oral Surgery
The purpose of this study is to explore the pain-relieving effects and safety of two analgesic treatment regimens as compared to placebo in patients experiencing pain after oral surgery.
- Trial name
- NCT00236483
- Testing
- tramadol hydrochloride + acetaminophen
- Volunteers
- 456 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Dental Anxiety
Evaluation of Dental Anxiety in Second-Stage Implant Surgery With Er,Cr:YSGG Laser
Implants embedded under the oral mucosa were exposed with scalpel (Group 1) or laser surgery (Group 2). Before the operation the patients were asked to fill the State-Trait Anxiety Inventory (STAI) and Dental Anxiety Scale (DAS)…
- Trial name
- NCT03871101
- Testing
- Scalpel, 2780 nm Er,Cr:YSGG Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Cleft Palate
Improving Outcomes in Cleft Palate Surgery
This is a pilot study to determine if an audit and feedback intervention decreases complication rates after cleft palate surgery.
- Trial name
- NCT02583100
- Testing
- Intensive Feedback, Routine Feedback
- Where
- 6 sites in United States, Canada
- Volunteers
- 7 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Orthognathic Surgery
Advanced Multimodal Anesthesia Care for Patients Undergoing Oro-maxillofacial Surgery
The purpose of this research is to develop from enhanced multimodal anesthesia care to verify and optimize ERAS strategies for orthognathic surgery.
- Trial name
- NCT05485246
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Maxillofacial Abnormalities, Maxillofacial Injuries
Vitamin C Level Effect in Orthognathic Surgery
Comparing the pre and post-operative blood plasma levels of vitamin C according to oxidative stress and investigate the correlation between post-operative analgesia requirement and vitamin C levels following orthognathic surgery.
- Conditions
- Maxillofacial Abnormalities, Maxillofacial Injuries, Maxillofacial Trauma
- Trial name
- NCT04416386
- Testing
- Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Oroantral Communication, Acute Oroantral Communication
Acute Oroantral Communication Closure: Resorbable Collagen Membrane vs. Buccal Advancement Flap Outcomes
Oroantral communication (OAC) is an abnormal opening between the oral cavity and the maxillary sinus that may occur after extraction of posterior maxillary teeth.
- Conditions
- Oroantral Communication, Acute Oroantral Communication, Oroantral Fistula, Post-extraction Maxillary Sinus Communication
- Trial name
- AOC (NCT07476664)
- Testing
- Resorbable collagen membrane OAC closure, Buccal advancement flap OAC closure
- Where
- Poland
- Volunteers
- 24 people
- Sponsor
- Medical University of Silesia
Postoperative Pain
Peripheral Nerve Block Techniques During Cleft Palate
Regional blocks are commonly used in pediatric anesthesia to achieve adequate postoperative analgesia. Suprazygomatic Maxillary nerve block (SMN) and Greater Palatine nerve block (GPN) are regional blocks described for use during…
- Trial name
- NCT04467463
- Testing
- peripheral nerve block by 0.25% levobupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Impacted Mandibular Third Molar, Postoperative Pain
Effect of Preoperative Long-Acting Corticosteroids on Pain, Swelling, and Trismus After Impacted Lower Third Molar Surgery
This study evaluated whether giving a single dose of long-acting corticosteroids before wisdom tooth surgery reduces pain, facial swelling, and limited jaw opening (trismus) after surgery.
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Facial Swelling
- Trial name
- NCT07450638
- Testing
- Dexamethasone 8 mg IM, Normal Saline IM
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al Salam University
Dentofacial Deformities
Splintless Virtual Surgical Plan with Mandible-first Technique: 3D Accuracy Analysis
Accuracy assessment through three-dimensional superposition of the post-operative volumetric CT and the digital therapeutic project files.
- Trial name
- MandiFirst (NCT06907745)
- Testing
- Bimaxillary Osteotomy
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Cannabis Use
Cannabis Use on Sedation for Oral Surgery Procedures
The use of Cannabis is increasing in the population, and the effects that this might have on different medical procedures are poorly understood.
- Trial name
- NCT05873465
- Testing
- Sedation with Midazolam, Fentanyl, and Propofol, Extraction of teeth
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Malocclusion, Abnormalities, Jaw
Personalized Titanium Plates vs CAD/CAM Surgical Splints in Maxillary Repositioning of Orthognathic Surgery
The purpose of this study is to determine whether personalized titanium plates can achieve better accuracy than CAD/CAM surgical splint in maxilla repositioning in orthognathic surgery, and evaluate the feasibility of this…
- Trial name
- NCT02914431
- Testing
- 3D Printing Personalized Titanium Plate
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Impacted Third Molar Tooth
Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution.
- Trial name
- NCT03179813
- Testing
- Hydrocortisone, Control
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Odontogenic Cyst, Jaw Cysts
Bone Regeneration Using PRF After Cyst Enucleation
This randomized controlled clinical trial aims to evaluate the clinical efficacy of autologous platelet-rich fibrin (PRF) in promoting osseous regeneration following cystic enucleation in the jaws.
- Conditions
- Odontogenic Cyst, Jaw Cysts, Osseous Defect After Cyst Enucleation
- Trial name
- PRF-Bone (NCT07424716)
- Testing
- Autologous Platelet-Rich Fibrin (PRF), Conventional Surgical Management
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Epithelial Odontogenic Tumours
Confrontation Phenotypes and Genotypes of Epithelial Odontogenic Tumors of the Jaws
Systematically compare the phenotype and genotype of epithelial odontogenic tumors in children and adults with a clinical, radiographic, pathologic and molecular level.
- Trial name
- TEIOS (NCT02167581)
- Where
- France
- Volunteers
- 319 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Other Surgical Procedures
Comparison of the Clinical Efficacy of Ketoprofen, Associated or Not With Omeprazole in Lower Third Molar Removal
The control of pain, swelling and trismus in patients undergoing oral and maxillofacial surgery is frequently performed through the administration of non-steroidal anti-inflammatory drugs (NSAIDS).
- Trial name
- NCT02730026
- Testing
- Ketoprofen, Ketoprofen and Omeprazole
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Luis Fernando Simoneti
Wound Healing, Wound Healing Complication
Sutureless Versus Conventional Suturing in Oral Surgery
This randomized clinical study compares sutureless wound closure using n-butyl-2-cyanoacrylate tissue adhesive with conventional silk suturing following minor oral surgical procedures.
- Conditions
- Wound Healing, Wound Healing Complication, Postoperative Pain, Oral and Maxillofacial Surgery Complications
- Trial name
- NCT07856524
- Testing
- Sutureless Wound Closure Using n-Butyl-2-Cyanoacrylate, Conventional Suturing
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- Jouf University
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Plugs in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) plugs help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07484997)
- Testing
- Concentrated Growth Factor (CGF) Plug
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University