Clinical trials: Measure Development
Autism
Pilot Study of the Effect of Hyperbaric Oxygen Treatment on Behavioral and Biomarker Measures in Children With Autism
The purpose of this study is to increase the understanding of the effect of Hyperbaric Oxygen Treatment (HBOT) on the behavior and functioning of children with autism.
- Trial name
- HBOT (NCT00584480)
- Testing
- Hyperbaric Oxygen Treatment (HBOT)
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
Reliability Study Using Electrodermal Activity to Measure Sensory Processing in Children With and Without Autism Spectrum Disorder
The purpose of this study is tTho establish test-retest reliability of electrodermal markers used to quantify physiologic response to sensation using the Sensory Challenge Protocol in children with and without Autism Spectrum…
- Trial name
- NCT02646696
- Testing
- Sensory Challenge Protocol
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Barpak Geriatric Health Services, Inc. d/b/a Barpak Occupational Therapy
Sports Injuries, Social Impact
Development Study of Pain Monitoring and Injury Impact Scale
This study introduced and validated the Pain Monitoring and Injury Impact Scale for Athletes (PAMIIS), developed to address the lack of a comprehensive tool in Turkish for assessing injury-related pain and its multidimensional…
- Conditions
- Sports Injuries, Social Impact, Psychological Impact of Injury
- Trial name
- PAMIIS (NCT06955364)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Gazi University
Epilepsy
Epilepsy Impact Scale
The investigators are developing a questionnaire that can quickly measure the impact that epilepsy has on a person's life. This questionnaire will be useful in following whether the impact of epilepsy increases, decreases or…
- Trial name
- NCT01833234
- Testing
- Interviews and questionnaires
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Hypertension, Aortic Aneurysm
Measurement of Heart-carotid Pulse Wave Velocity (hcPWV) by Laser Doppler Vibrometry (LDV)
Aortic stiffness is an important imaging biomarker of vascular aging. The ascending aorta is the most elastic segment, and it is excluded by reference non-invasive method carotid to femoral pulse wave velocity (PWV).
- Conditions
- Hypertension, Aortic Aneurysm, Bicuspid Aortic Valve, Marfan Syndrome
- Trial name
- InSide-CC (NCT05711693)
- Testing
- Laser doppler vibrometry (LDV), heart(cordium) carotid pulse wave velocity (ccPWV), Blood pressure and heart rate measurement, carotid to femoral PWW measurement
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pelvic Floor Disorders
Development of a Pelvic Cavity Characterization Algorithm Through the Acquisition of MRI Images and Pressure Measurement by an Intravaginal Probe
The conditions such as childbirth or endometriosis can lead to a change in the mobility of the pelvic organs (bladder, vagina, rectum and uterus).
- Trial name
- MI-IRM (NCT04319653)
- Testing
- Dynamic pelvic MRI with intravaginal probe with pressure sensor
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Lille
Hepatitis B Virus Related Cirrhosis, Portal Hypertension Related to Cirrhosis
Hepatic and Splenic Microcirculatory Perfusion for Ruling Out High-Risk Varices in Patients With Hepatitis B-Related Cirrhosis
Background: Chronic hepatitis B (CHB)-related cirrhosis is a common cause of portal hypertension, which leads to the development of gastroesophageal varices (EGVs).
- Conditions
- Hepatitis B Virus Related Cirrhosis, Portal Hypertension Related to Cirrhosis, Esophagogastric Varices
- Trial name
- NCT07450651
- Volunteers
- 150 people
- Sponsor
- Beijing Friendship Hospital
DDX3X, Mental Retardation, X-linked 102
DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.
DDX3X syndrome is a genetic cause of intellectual disability and other neurologic features including, in some cases, autism. Variants in the DDX3X gene are thought to account for 1-3% of unexplained intellectual disability in…
- Conditions
- DDX3X, Mental Retardation, X-linked 102, Autism Spectrum Disorder
- Trial name
- NCT03718910
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cancer of the Oral Cavity
Quality of Life and Development of Measures in Patients With Cancer of the Oral Cavity
The purpose of this study is to learn more about the quality of life and emotional changes that patients experience during their treatment for cancer of the mouth.
- Trial name
- NCT00582413
- Testing
- questionnaires
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Autistic Disorder
Extended Management and Measurement of Autism
This open-label research study will continue to monitor the safety of fluoxetine in children after their completion of a previous double-blind placebo controlled clinical study, with fluoxetine.
- Trial name
- EMMA (NCT00787111)
- Testing
- Fluoxetine (prozac)
- Where
- 13 sites in United States
- Volunteers
- 128 people
- Sponsor
- Neuropharm
Rett Syndrome
Development of a Behavioral Outcome Measure for Rett Syndrome (RettBe)
The overall purpose of this study is to develop a broad-based (i.e., multiple domains) behavioral outcome measure for children between the ages of 3-18 years with Rett syndrome (RTT).
- Trial name
- NCT03196323
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- University of South Florida
Breast Cancer
Development and Assessment of the 8-item Chronic Pain Acceptance Questionnaire to Measure Disease Acceptance in Women With Breast Cancer
This observational study was conducted to develop and test a new self-report questionnaire, the Cancer Pathology Acceptance Questionnaire for Breast Cancer (CPAQ-8-BC), specifically adapted for women diagnosed with Breast Cancer…
- Trial name
- CPAQ-8-BC (NCT07328321)
- Testing
- Cancer Pathology Acceptance Questionnaire
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- G. d'Annunzio University
Disorders of Gut Brain Interaction
Development of a Noninvasive Metric to Measure Small Bowel Sensation - The Small Intestine Stress Test
The purpose of this research is to identify the concentration of mannitol solution (a type of sugar alcohol) that will generate a range of symptoms in individuals without Disorders of Gut Brain Interaction (DGBI) to establish the…
- Trial name
- NCT07817706
- Testing
- Mannitol Solution 76 mOsm/L, Mannitol Solution 189 mOsm/L, Mannitol Solution 325 mOsm/L
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Respiratory Disorder, Diabetes
The Measurement of VItal SIgns by Lifelight® Software in comparisON to the Standard of Care - Multi-site Development
AIM: To advance the development and accuracy of the Lifelight® app for the measurement of vital signs, therefore developing a non-invasive and easy-to-perform means of measuring vital signs which can be implemented across a wide…
- Conditions
- Respiratory Disorder, Diabetes, Cardiovascular Diseases, Critical Care
- Trial name
- VISION-MD (NCT04763746)
- Testing
- Lifelight Data Collect Sub-protocol 1, Lifelight Data Collect Sub-protocol 2, Lifelight Data Collect Sub-protocol 3
- Where
- United Kingdom
- Volunteers
- 1,869 people, healthy volunteers welcome
- Sponsor
- Xim Limited
Autism Spectrum Disorder
Interest of Oxytocin as an Adjuvant Treatment of Psycho-educational Measures in Challenging Behaviors in Children With Autism Spectrum Disorders and Moderate to Severe Intellectual Disability: Feasibility and Safety Study.
The investigation team propose in this study to specifically evaluate the feasibility of using oxytocin in the form of an intranasal spray in a specific population of children with autism spectrum disorder and intellectual…
- Trial name
- OT-DEFI (NCT05864508)
- Testing
- Oxytocin nasal spray
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Frailty, Oncology
Approaches and Metrics in Fraily Patients During COVID-19 Era
The COVID-19 pandemic started in December 2019 in Wuhan, the Chinese province of Hubei. Compared to the period of the first epidemic wave (March to May 2020), in the period of the second epidemic wave (October 2020 to July 2021)…
- Conditions
- Frailty, Oncology, Immune Deficiency
- Trial name
- COMETA (NCT05792891)
- Testing
- Collecting biological material from frail patients, with or without COVID-19
- Where
- 2 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Renal Failure, End Stage Renal Disease
Development, Feasibility Testing and Validation of a Survey Set to Measure Patient-Reported Outcomes Among Hemodialysis Patients in Turkey
Development, feasibility testing and validation of a Survey Set to Measure Patient-Reported Outcomes among Hemodialysis Patients in Turkey: Creating and testing an electronic patient questionnaire that is suitable to measure…
- Trial name
- DOPRO (NCT05441020)
- Testing
- Administration of patient questionnaire
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 173 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Fatigue
Measure of Fatigue in Functional MRI
The purpose of this study is to determine more objective, central and peripheral indices of fatigue state by exploring the neural and behavioral correlates of the alert process while keeping the idea to corroborate these results…
- Trial name
- FATIGUE (NCT02379013)
- Testing
- Volunteer with MRI
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hôpital NOVO
Autism Spectrum Disorder
Structural and Functional Connectivity in Autism Spectrum Disorders
Autism spectrum disorder (ASD) has been given a high priority for genetic and neurobiological study. There is no such information in Asian population and no study has conducted using Diffusion Spectrum Imaging (DSI) to…
- Trial name
- NCT00755430
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Genu Varum, Genu Valgus
IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms
While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether…
- Conditions
- Genu Varum, Genu Valgus, Flat Feet, Cavus Foot
- Trial name
- MOTOR-CHILD (NCT05763901)
- Testing
- Clinical tests and motor control evaluation using Inertial Measurement Units
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Istituto Ortopedico Rizzoli