Clinical trials: Measure Development
Financial Hardship, Alzheimer's Disease (AD)
Development of Measures to Screen for Financial Hardship in Alzheimer's Disease and Dementia
Alzheimer's Disease and related dementias (AD/ADRD) are common and debilitating conditions. Financial hardship, a multidimensional construct of financial strain, financial stress and asset depletion, is common in AD/ADRD due to…
- Conditions
- Financial Hardship, Alzheimer's Disease (AD), Alzheimer's Disease and Related Dementia (ADRD)
- Trial name
- AD/ADRD (NCT06922188)
- Where
- United States
- Volunteers
- 2,460 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Autism, Autism Spectrum Disorder
Validation Digital Bio-markers During Sulforaphane Treatment.
The purpose of the research is to determine if changes seen during sulforaphane treatment (a compound that comes from eating certain vegetables) can better be understood using digital biomarkers.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder
- Trial name
- NCT04805957
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey
Coccidioidomycosis, Disseminated Fungal Infection
A Phase II Randomized Study to Evaluate Measures for Endpoint Derivation in Patients With Progressive or Refractory Disseminated Coccidioidomycosis Treated With Olorofim Plus Baseline Standard of Care or Placebo Plus Baseline Standard of Care
The purpose of this study is to test measurement tools (questionnaire about symptoms and a questionnaire about quality of life) to assess usability in the assessment of treatment effectiveness for people with disseminated…
- Conditions
- Coccidioidomycosis, Disseminated Fungal Infection, Coccidioides Infection, Coccidioides Immitis Infection
- Trial name
- COCCIMETRICS (NCT07712484)
- Testing
- Olorofim
- Volunteers
- 50 people
- Sponsor
- F2G Ltd
Cystic Fibrosis
Development Of An Innovative Panel of Methods To Measure Intestinal Macronutrient Digestion, Absorption, and Function
Malnutrition is a significant problem in children and adults with Cystic fibrosis (CF). An impaired intestinal digestion and absorption capacity is one of the main factors responsible for the malnutrition in CF.
- Trial name
- NCT01494909
- Testing
- Ensure plus
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
COPD (With - Without Rehabilitation), Diffuse Interstitial Lung Diseases
Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases
The purpose of this study is the psychometric validation of a self-administered dyspnea questionnaire, usable in clinical practice in order to assess dyspnea and its impact on patients with chronic respiratory diseases.
- Conditions
- COPD (With - Without Rehabilitation), Diffuse Interstitial Lung Diseases, Pulmonary Arterial Hypertension Primary or Secondary (Post Embolic .....), Cystic Fibrosis of the Adult
- Trial name
- DYSLIM (NCT02229994)
- Testing
- Cross sectional psychometric evaluation of a self-administered dyspnea questionnaire.
- Where
- France
- Volunteers
- 199 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Duchenne / Becker Muscular Dystrophy, Osteogenesis Imperfecta (OI)
Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders
The primary aim of this observational study is to investigate specific aspects of social cognition in dystrophinopathies. Body awareness, interpersonal distance and emotional processing will be measured in a sample of patients…
- Conditions
- Duchenne / Becker Muscular Dystrophy, Osteogenesis Imperfecta (OI), Social Cognition
- Trial name
- NCT06874166
- Testing
- Electroencephalography (EEG), Social Cognition Tasks
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Mental Health Conditions, Physical Health Status
Prospective Cohort Study of Protected Children
A significant number of children are abused or neglected every year. This exposure is associated with short- and long-term consequences for their mental and somatic health.
- Conditions
- Mental Health Conditions, Physical Health Status, Child Development
- Trial name
- ESPER (NCT06805682)
- Testing
- Usual Care
- Where
- 7 sites in France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorders, Autism
Measurement of Joint Attention Fluency
The purpose of this research is to study joint attention. Joint attention plays a critical role in social and language development in children with and without autism.
- Trial name
- NCT01643343
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Vista School
Hiv, Medication Adherence
Development of a Silica Microparticle Taggant System to Measure ART Adherence
Developing technologies to help measure and provide tools to support medication-taking behaviors (medication adherence) is an important step to ending the human immunodeficiency virus (HIV) epidemic.
- Conditions
- Hiv, Medication Adherence, Compliance, Medication
- Trial name
- TruTag (NCT06465862)
- Testing
- TruTag System, Biktarvy Pill
- Sponsor
- Brigham and Women's Hospital
Abdominal Surgery
Development of a Patient-Reported Outcome Measure to Assess Recovery After Abdominal Surgery
As surgery enters the era of value-based care, it is advocated that postoperative recovery be measured using patient-reported outcomes (PROs) as they provide a mean to incorporate the patient's perspectives and experiences into…
- Trial name
- NCT03461497
- Where
- 7 sites in United States, Brazil and 3 more
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Autistic Disorder
Trial of Methyl B12 on Behavioral and Metabolic Measures in Children With Autism
The purpose of this study is to determine whether the supplement Methyl B12 is effective in treating some of the symptoms of Autism.
- Trial name
- B12 (NCT01039792)
- Testing
- Methyl B12
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of California, San Francisco
Fall Risk
Development of an Acceleration Based Fall Risk Detector
Because the increasing fall problem, mainly due to an impaired gait and balance ability, this study will investigate fall risk by detecting fall related movement characteristics.
- Trial name
- field (NCT00767429)
- Testing
- fall risk detector
- Where
- 4 sites in Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Ulcerative Colitis
Development of Novel Imaging and Molecular Biomarkers of Fibrosis in Patient With Ulcerative Colitis
Prospective multicenter interventional non-randomized cross-sectional study. Ultrasound operators will be blinded to clinical and endoscopic findings and the endoscopist will be blinded of the clinical and ultrasound findings.
- Trial name
- NCT06516237
- Testing
- to determine molecular and epigenetic biomarkers
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Gait, Child Development
Reproducibility Inter-session of the Measurement Elastography of the Passive Stiffness of Medial Beams of Gastrocnemius Muscle of the Hemiplegic Cerebral Child.
Muscles, paretics and spastics, of cerebral palsy children have very early, for growth (three at five aged), every alteration of theirs properties.
- Conditions
- Gait, Child Development, Hemiplegic
- Trial name
- ELASTOREPRO (NCT02960932)
- Testing
- ultrasound scanner
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Schizophrenia, Cognition Disorders
Schizophrenia Cognition Scale Development
The objective of this protocol is to develop items for a patient-reported outcome (PRO) measure to assess the patient's perspective and subjective experience of cognitive impairment associated with schizophrenia (CIAS).
- Trial name
- CIAS PRO (NCT02118571)
- Where
- 4 sites in United States
- Volunteers
- 102 people
- Sponsor
- Carelon Research
Medical Device
Development of a Segmental Bioelectrical Impedance Spectroscopy Device for Body Composition Measurement
A device for measuring body composition with a small electric current, at 200 μA, (bioelectrical impedance analysis, or BIA) was designed.
- Trial name
- NCT04006899
- Testing
- Bioelectrical Impedance Monitor
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Jun Choi
Essential Tremor, Dystonia
The Development of a System for Measurement of Tremor
The goal of this clinical trial is to develop a system which can be used to measure movements in people with Essential Tremor (with or without dystonia).
- Trial name
- NCT05956223
- Testing
- Virtual Reality measurement of essential tremor and dystonia
- Where
- Australia
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- The Bionics Institute of Australia
Psychometric
Scale Development for Organizational Trustworthiness
The Teaming Researchers Up with Stakeholders to Test Trustworthy Engagement and Measure (TRUST TEAM) project seeks to better understand the role of organizational trustworthiness in the context of community-engaged research.
- Trial name
- TRUST TEAM (NCT07358559)
- Testing
- Questionnaire
- Volunteers
- 1,035 people
- Sponsor
- The Hastings Center for Bioethics
Correlation of cFDNA During CPB to Laboratories SIRS Parameters and Clinical Outcomes
Measurement of Circulating Cell-free DNA (cfDNA) for Diagnosis and Prognosis of Various Diseases and Evaluation of Tissue Damage
To characterize the changes in circulating cell-free DNA (cfDNA) levels during cardiopulmonary bypass (CPB) and to access their association with outcomes compared to standard scores.
- Trial name
- NCT05094960
- Testing
- Blood samples
- Volunteers
- 71 people
- Sponsor
- Soroka University Medical Center
Osteoarthritis, Avascular Necrosis
Metal Ions in Ceramic on Metal Total Hip Arthroplasty
The investigators aim to measure the blood levels of certain metals in a group of patients all of whom have had a ceramic on metal total hip replacement.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Developmental Dysplasia of the Hip
- Trial name
- COM (NCT01437124)
- Where
- United Kingdom
- Volunteers
- 83 people
- Sponsor
- Hussain Kazi