Clinical trials: Measure Development
Thyroid Diseases
Health-Related Quality of Life for Thyroid Patients
Background: Thyroid diseases are frequent. They include both metabolic changes and gland enlargement (goitre). Previous research and clinical suspicion indicate that the life quality of many patients is reduced despite successful…
- Trial name
- NCT00150033
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Odense University Hospital
Klinefelter Syndrome, Diabetes
Body Composition, Bone Mineral Density, Insulin Sensitivity and Echocardiographic Measurements in Klinefelter Syndrome
Klinefelter syndrome (KS) is the most common sex-chromosome disorder with a prevalence of one in 660 men and is a frequent cause of hypogonadism and infertility.
- Conditions
- Klinefelter Syndrome, Diabetes, Osteoporosis, Metabolic Syndrome
- Trial name
- NCT00523835
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy
Measurement of the Folate Receptor in Blood
The folate receptor (FR) is a cell marker that is over expressed on the cell surface of certain cancers, this occurs most frequently in ovarian cancers.
- Trial name
- NCT00838747
- Where
- United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Urinary Incontinence
Collecting Real-life Data for the Updated TENA SmartCare Change Indicator.
This study is an explorative, open, single-arm clinical investigation to collect real-life measurement data in order to assess the mathematical algorithms involved in TENA SmartCare Change Indicator.
- Trial name
- NCT06092099
- Testing
- TENA SmartCare Change Indicator
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Essity Hygiene and Health AB
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Multiple Myeloma
A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
Multiple Myeloma (MM) is a cancer of the blood's plasma cells ( blood cell). The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bones) and can cause bone pain, fractures, infections…
- Trial name
- NCT05650632
- Testing
- Etentamig (ABBV-383)
- Where
- 46 sites in United States, Canada and 5 more
- Volunteers
- 210 people
- Sponsor
- AbbVie
Lower Limb Loss
Musculoskeletal Measurements in Transfemoral Amputees
The aim of this study was to identify posture asymmetries in transfemoral amputees utilizing clinical evaluation measures. The purposes of this investigation were: 1) to measure the limb length indirectly to determine the…
- Trial name
- NCT00909922
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Miami VA Healthcare System
Electrical Status Epilepticus in Sleep
Study of Patients with Electrical Status Epilepticus in Sleep
Our aims are: 1. To understand the diagnostic practices, treatment and long term management and outcomes for patients diagnosed with ESES locally. 2.
- Trial name
- SPESES (NCT06792396)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- East Suffolk and North Essex NHS Foundation Trust
Pediatric Pain
Development of a New Electronic Measure of Pediatric Pain: A Pilot Study
The purpose of this study is to test the accuracy of a computer-based program to self-report the location and intensity of a child's pain in comparison to a traditional self-report paper and pencil measure and physician physical…
- Trial name
- NCT00884780
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Mercy Hospital Kansas City
Cystic Fibrosis
Development and Validation of a Disease Specific PROM to Assess Abdominal Involvement in Patients With CF (CFAbd-Score)
Development, validation and evaluation of a new multimodal questionnaire to assess and quantify the abdominal involvement in patients with the inherited life shortening multi-organ disease Cystic fibrosis.
- Trial name
- CFAbd-Score (NCT03052283)
- Testing
- Questionnaire Patient Reported Outcome Measure (PROM)
- Where
- 2 sites in Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Depression
Vocal Acoustic Biomarkers in Depression
This Phase II SBIR study will replicate pilot study methods establishing computer-automated methods for assessing depression severity using interactive voice response system technology and demonstrating feasibility of obtaining…
- Trial name
- Speech2 (NCT00844948)
- Where
- 2 sites in United States
- Volunteers
- 125 people
- Sponsor
- Center for Psychological Research, Madison, WI
Labour Pain
Development of a Multi-attribute Health Index: to Measure the Quality of Labour Analgesia: The QLA Index
The findings of this research will be used to develop a scale for measuring the quality of epidural pain relief achieved during labour and vaginal delivery.
- Trial name
- NCT01177046
- Where
- Canada
- Volunteers
- 752 people
- Sponsor
- Sunnybrook Health Sciences Centre
Infant Development, Infant Overnutrition
Measurement of Energy Metabolism in Infants
The purpose of this study is to measure energy expenditure during the first 3 months of life in infants.
- Trial name
- BabyEE Pilot (NCT02683473)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Shoulder Lesions, Shoulder Injuries
Development a New Scale for Assessment Shoulder Problems
The purpose of this study is to develop and psychometrically validate the Shoulder Problems Assessment Scale (SPAS), a culturally grounded patient-reported outcome measure designed to assess shoulder-related functional…
- Conditions
- Shoulder Lesions, Shoulder Injuries, Shoulder Pain
- Trial name
- NCT05391516
- Testing
- Evaluation of shoulder problems
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Suleyman Demirel University
Cancer, Cardiovascular Diseases
Development of Photoacoustic Tomography
Cancer is one of the leading causes of death internationally. When planning treatment for most cancers, it is important to know how far it has spread, including whether or not the cancer has spread to the local lymph nodes (LNs)…
- Trial name
- NCT03501823
- Testing
- Photoacoustic tomography
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University College, London
Growth Hormone Deficiency
Impact of GH Measurements on GHD Diagnosis
Human growth hormone (hGH) provocation test is an essential tool to assess growth hormone deficiency in children and young adults. It is important to have a robust and reliable method to determine the hGH peak of stimulation.
- Trial name
- NCT04508673
- Testing
- GH provocation tst
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Montpellier
Epidemiology of Cardiovascular Risk
Selection of People at Low Cardiovascular Risk: Development of an Inexpensive Pre-screening Algorithm Using Only Non-laboratory Measures. The SKIM Risk Study.
Early identification of individuals at high risk remains the cornerstone of primary cardiovascular prevention (CV). However, cardiovascular screening including people at low CV diseases (CVD) risk are too costly, time consuming…
- Trial name
- SKIM (NCT03962309)
- Testing
- Health self-assessment questionnaire
- Where
- 3 sites in Italy
- Volunteers
- 2,699 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Bronchopulmonary Dysplasia
MRI in BPD Subjects
The investigators are wanting to learn more about early development of the lungs and to help them better understand prematurity and the development of a breathing disorder call BPD (Bronchopulmonary Dysplasia)
- Trial name
- NCT03657693
- Testing
- NICU MRI, Polysomnography
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Nursing Education, Vital Signs
Game-Based 3D Simulation for Vital Signs Training in Nursing Education
This study aims to improve nursing students' skills in measuring vital signs using a 3D animation-based game simulation. Measuring vital signs is a key responsibility for nurses and requires both knowledge and hands-on practice.
- Conditions
- Nursing Education, Vital Signs, Animation, Academic Acheivement
- Trial name
- NCT07009275
- Testing
- The game-based simulation application developed using 3D animation technology
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Disorders of Gut Brain Interaction
Development of a Noninvasive Metric to Measure Small Bowel Sensation - The Small Intestine Stress Test
The purpose of this research is to identify the concentration of mannitol solution (a type of sugar alcohol) that will generate a range of symptoms in individuals without Disorders of Gut Brain Interaction (DGBI) to establish the…
- Trial name
- NCT07817706
- Testing
- Mannitol Solution 76 mOsm/L, Mannitol Solution 189 mOsm/L, Mannitol Solution 325 mOsm/L
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic