Clinical trials: Mechanical Insufflation-exsufflation
Neuromuscular Diseases
Changes in Regional Lung Ventilation Following Mechanical Insufflation-Exsufflation
Patients with NMD can suffer from a range of respiratory problems due to respiratory muscle weakness. Cough muscle weakness worsens secretion clearance from the airways, and increases the risk of infection.
- Trial name
- MIE and EIT (NCT02753959)
- Testing
- Acute Intervention, Stable Intervention
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cough, Airway Clearance Impairment
Does the Coaching Function Improve the Learning of Mechanical In-exsufflation (MI-E) in Paediatric Subjects?
The use of mechanical insufflation-exsufflation (MI-E) in children with neuromuscular diseases (NMD) is recommended by international guidelines and societies and well documented.
- Conditions
- Cough, Airway Clearance Impairment, Neuromuscular Diseases
- Trial name
- MI-Ecoaching (NCT06190431)
- Testing
- Learning the use of an in-exsufflation device with the guidance of a physiotherapist, Using the coaching mode
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Respiratory Failure
The Effects of Mechanical Insufflation-exsufflation on Airway Mucus Clearance in the ICU
The present study aims to evaluate the effect of mechanical insufflation-exsufflation on airway mucus clearance among mechanically ventilated ICU patients.
- Trial name
- NCT03178565
- Testing
- Mechanical insufflation-exsufflation, Standard Respiratory Physiotherapy
- Where
- Brazil
- Volunteers
- 170 people
- Sponsor
- Hospital Moinhos de Vento
Mucus Retention, Mechanical Ventilation Complication
Effects of Mechanical Insufflation-Exsufflation With Optimized Settings on Wet Mucus Volume During Invasive Ventilation
Retention of airway secretions is a frequent complication in critically ill patients requiring invasive mechanical ventilation (MV).This complication is often due to excessive secretion production and ineffective secretion…
- Trial name
- NCT06491017
- Testing
- MI-E Intervention protocol, Standard MI-E setting
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Ventilator Associated Pneumonia, Brain Injuries
M-I/E for Preventing VAP in Post-neurosurgical Patients
Ventilator-associated pneumonia (VAP) is a common infection in critically ill patients, especially those with acute brain injuries, leading to increased mortality and longer ICU stays.
- Conditions
- Ventilator Associated Pneumonia, Brain Injuries, Mechanical Insufflation-exsufflation
- Trial name
- NCT06511986
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Beijing Sanbo Brain Hospital