Clinical trials: Mechanical Ventilation Weaning
Bronchopulmonary Dysplasia
Pressure-Sensing Mattresses and Mechanical Ventilation Weaning in Neonatal
This study aims to explore the correlation between using ballistocardiography for monitoring respiration and heart rate in neonates under invasive and non-invasive respiratory support.
- Trial name
- NCT06579157
- Testing
- Pressure-Sensing Mattresses
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fu Jen Catholic University
Ventilator Weaning, Intensive Care Unit
Use of Transient Elastogaphy to Assess Diaphragm Function in Mechanically Ventilated Patients
Mechanical ventilation is a life-saving treatment that can be associated with diaphragm dysfunction, a potentially deleterious acquired disability.
- Trial name
- Elasto-ICU (NCT03832231)
- Testing
- Shear Wave Elastography
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Weaning, Spontaneous Breathing Trial
Diaphragmatic Speckle Tracking During Spontaneous Breathing Trial
Currently, measurement of transdiaphragmatic pressure (Pdi) using oesophageal and gastric balloons is the gold standard for the assessment of diaphragmatic effort.
- Conditions
- Weaning, Spontaneous Breathing Trial, Mechanical Ventilation, Speckle Tracking
- Trial name
- DIAST (NCT06009731)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Mechanical Ventilation
Ultrasonography Guided Weaning Protocol Development to Predict Successful Weaning
The investigators aimed to develop integrated ultrasound guided mechanical weaning protocol in critically ill patients. The analysis will be taken (1) just before the spontaneous breathing trial in enrolled patients with…
- Trial name
- NCT03574233
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Mechanical Ventilation, Following Heart or Abdominal Surgery
Cardiac, Pulmonary and Diaphragm Sonography for the Early Diagnosis of the Different Etiologies Underlying Failure of Weaning From Mechanical Ventilation
Weaning patients off ventilation in an ICU is sometimes difficult, because of three major inter-related etiologies: impaired lung, heart and diaphragm function.
- Trial name
- WEAN US (NCT03261440)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Diaphragmatic Ultrasound in Weaning
Diaphragmatic Ultrasound as a Guide Tool During Weaning From Mechanical Ventilation
To assess value of adding ultrasound derived variables to the usual parameters on success rate of weaning from mechanical ventilation in critically ill patients and to validate sensitivity and specificity of ultrasound derived…
- Trial name
- NCT03608332
- Testing
- diaphragmatic ultrasound
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Cairo University
Mechanical Ventilation, Weaning From Mechanical Ventilation
Temporal Change in Parasternal Thickening Fraction as a Predictor for Weaning
optimal time to liberate from mechanical ventilation is highly prioritized since improper extubation time lead to serious consequences
- Conditions
- Mechanical Ventilation, Weaning From Mechanical Ventilation, Weaning Failure
- Trial name
- NCT07083128
- Testing
- Parasternal intercostal thickening
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Mechanical Ventilation Complication, Pulmonary Edema
Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)
The purpose of this study is to determine if the left and right ventricular systolic function is involved in the development of weaning failure related to weaning-induced pulmonary edema.
- Trial name
- SystoWean (NCT05226247)
- Testing
- Spontaneous breathing trial
- Where
- 3 sites in France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Mechanical Ventilation Weaning
Feasibility Study to Compare Two Ventilatory Modes for Mechanical Ventilation Weaning
We hypothesize that the ventilatory mode Bilevel Positive Airway Pressure without any synchronization (BIPAPasynchro) may facilitate the weaning process of patients intubated with acute hypoxiemic respiratory failure (AHRF) by…
- Trial name
- BIWEAN (NCT06912906)
- Testing
- BIPAPasynchro: byphaisc positive pressure modality without any synchronisation
- Where
- 2 sites in Switzerland
- Volunteers
- 84 people
- Sponsor
- University of Lausanne Hospitals
Respiratory Muscle Weakness, Mechanical Ventilation Weaning
Progressive Pressure Support Reduction as Inspiratory Muscle Endurance Training in Mechanically Ventilated Patients
Mechanical ventilation causes rapid diaphragm muscle atrophy, detectable within 18 hours of ventilator support, which is a major contributor to weaning failure and prolonged ICU stay.
- Conditions
- Respiratory Muscle Weakness, Mechanical Ventilation Weaning, Physiotherapy, Endurance Training
- Trial name
- inspira-rct (NCT07689110)
- Testing
- Progressive Pressure Support Reduction (IRT-PS), Standard ICU Care
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Santiago de Compostela
Ventilator Dependent
Short Effects of SIMT and EM in Prolonged Mechanically Ventilated Patients
Using mechanical ventilation for more than 18 hours can affect respiratory muscle and postural muscle control, making it difficult to wean off the ventilator and reducing mobility. The aim of this study is to: 1.
- Trial name
- NCT06368089
- Testing
- Inspiratory muscle training (IMT) group, Early mobilization (EM) group
- Where
- Thailand
- Volunteers
- 46 people
- Sponsor
- Prince of Songkla University
Mechanical Ventilation Complication
Thoracic Fluid Content in Prediction of Failure of Weaning From Mechanical Ventilation
This study aims to test the accuracy of the total thoracic fluid content (TFC) measured by cardiometry can predict weaning failure.
- Trial name
- NCT03094390
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Critically Ill, Acute Respiratory Failure
Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study
For adult patients with acute respiratory failure requiring invasive mechanical ventilation, does a ventilation strategy using proportional assist ventilation with load-adjustable gain factors (PAV+) result in a shorter duration…
- Trial name
- PROMIZING (NCT02447692)
- Testing
- PSV ventilation strategy, PAV+ ventilation strategy
- Where
- 22 sites in Argentina, Canada and 5 more
- Volunteers
- 575 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hypnosis, Weaning Mechanical Ventilation
Hypnosis During Mechanical Ventilation Weaning
Hypnosis is defined as an altered state of consciousness characterized by an increased susceptibility to suggestion. It is a technique commonly used in the medical field, primarily for the management of pain and anxiety.
- Conditions
- Hypnosis, Weaning Mechanical Ventilation, Hypnosis During Weaning From Invasive Mechanical Ventilation
- Trial name
- HYPREA (NCT07518498)
- Testing
- Hypnosis
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
Prolonged Mechanical Ventilation
Effects of IMT on Weaning and Diaphragmatic Function in PMV Patients
Prolonged mechanical ventilation (PMV) and weaning failure can lead to extended hospital stays, as well as increased morbidity and mortality during hospitalization.
- Trial name
- NCT07200037
- Testing
- inspiratory muscle training
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Delirium
Study on the Incidence of Delirium in a Respiratory Weaning Centre
Delirium is rather common among patients in Intensive Care Units (ICU), while little is known about its incidence in ventilator-dependent patients transferred to a Weaning Center (WC), once in a phase of clinical stability.
- Trial name
- delricu (NCT00611377)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Salvatore Maugeri
Prolonged Mechanical Ventilation, Respiratory Failure
EIT-Guided Respiratory Physiotherapy for Prolonged Mechanical Ventilation (PMV)
Patients with prolonged mechanical ventilation (PMV) frequently experience impaired ventilation distribution, respiratory muscle dysfunction, secretion retention, and delayed liberation from mechanical ventilation.
- Conditions
- Prolonged Mechanical Ventilation, Respiratory Failure, Critical Illness
- Trial name
- PMV (NCT07372794)
- Testing
- EIT-Guided Respiratory Physiotherapy, Conventional Respiratory Physiotherapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Capital Medical University
Critical Care, Weaning
Cardiorespiratory Changes in Patients Being Weaned Off Mechanical Ventilation
The objective of this study was to analyze changes in cardiac function using Doppler echocardiogram in critical patients during weaning from mechanical ventilation using two different weaning methods (pressure support and T-tube)…
- Trial name
- NCT00852891
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Mechanical Ventilation With Oral Intubation, Weaning Invasive Mechanical Ventilation
Endotracheal Suctionning During Positive Pressure Extubation in ICU
The aim of this clinical trial is to evaluate endotracheal suctioning during positive pressure extubation in mechanically ventilated adult patients (over 18 years old) in the intensive care unit (ICU).
- Conditions
- Mechanical Ventilation With Oral Intubation, Weaning Invasive Mechanical Ventilation, Oxygen Saturation Measurement, Rox Index
- Trial name
- INTENTION (NCT07130123)
- Testing
- Suctionning extubation, No suctionning Extubation
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Weaning Failure
Lung Ultrasound for Predicting Outcome of Weaning From Mechanical Ventilation
Lung aeration loss can be measured via lung ultrasound, it is a non-invasive, bed side procedure, which can be performed rapidly and facilitates a dynamic assessment of lung aeration.
- Trial name
- NCT03880864
- Testing
- Ultrasound
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University