Clinical trials: Mechanically Ventilated ICU Patients
Critical Illness, Sedation
Analgosedative adjuncT keTAmine Infusion iN Mechanically vENTilated ICU Patients
The purpose of this study is to investigate the efficacy and safety of a low dose ketamine infusion used in combination of standard of care in critically ill patients to test whether ketamine can help to shorten the time of being…
- Conditions
- Critical Illness, Sedation, Mechanical Ventilation
- Trial name
- ATTAINMENT (NCT04075006)
- Testing
- Ketamine
- Where
- Saudi Arabia
- Volunteers
- 84 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
COVID-19, Bacterial Infections
Incidence of Colonization by Multidrug-resistant Organisms in Mechanically Ventilated Patients With Severe COVID-19
Retrospective single-center cohort study to evaluate the incidence of colonization by multidrug-resistant organisms (MDRO) in mechanically ventilated patients admitted to a large intensive care unit (ICU) for severe acute…
- Conditions
- COVID-19, Bacterial Infections, Colonization, Asymptomatic
- Trial name
- MDR_in_Fiera (NCT05293418)
- Testing
- data collection
- Where
- Italy
- Volunteers
- 435 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Intensive Care Unit Acquired Weakness
The Effect of Inspiratory Muscle Training on Diaphragmatic Function in Mechanically Ventilated Patients
In this study, the effect of inspiratory muscle training on diaphragmatic functions will be investigated radiologically in mechanically ventilated patients.
- Trial name
- NCT05303623
- Testing
- Conventional Physiotherapy, Conventional Physiotherapy+ inspiratory muscle training, inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Sedative Drug Consumption, Mechanically Ventilated ICU Patients
Efficacy of Music on Reduction of Sedative Drugs in Mechanically Ventilated Intensive Care Unit Patients
Major objective: a three-days interventional cross-over trial [one day music on, one day wash-out, one day music off][two periods of listening/day], to evaluate: 1. Impact on sedative drug consumption. 2.
- Trial name
- MUSIC (NCT00880035)
- Testing
- MP3 music program listening
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Université de Sherbrooke
Mental Health Issue
VR Collaboration System to Improve Mental Health Outcomes
Collaboration between family members and mechanically ventilated (MV) patients in the intensive care unit (ICU) is essential for improving patients' hospitalization experiences and outcomes.
- Trial name
- NCT05773131
- Testing
- VR collaborative visualization system
- Where
- China
- Volunteers
- 566 people
- Sponsor
- Peking Union Medical College Hospital
Gastric Ultrasound
Ultrasound Assessment of Gastric Emptying in Mechanically Ventilated ICU Patients
This prospective observational study aims to evaluate dynamic changes in gastric volume and gastric emptying time using bedside gastric ultrasound in mechanically ventilated intensive care unit patients.
- Trial name
- GASTRIC-USG (NCT07352202)
- Testing
- Enteral Nutrition (Routine Clinical Care)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Ventilator Weaning, Mechanical Ventilation
Comparison of Diaphragm Ultrasound and RSBI for Predicting Weaning Success in Mechanically Ventilated ICU Patients
The goal of this observational study is to evaluate the predictive value of diaphragmatic ultrasound compared to the Rapid Shallow Breathing Index (RSBI) in determining weaning success among mechanically ventilated patients in…
- Conditions
- Ventilator Weaning, Mechanical Ventilation, Respiratory Insufficiency Requiring Mechanical Ventilation, Weaning From Mechanical Ventilation
- Trial name
- NCT07120438
- Volunteers
- 55 people
- Sponsor
- Gadjah Mada University
Septic Shock, Mechanical Ventilation Complication
Adjunctive Esketamine for Analgesia in Mechanically Ventilated Septic Shock Patients
Sedation and analgesia in patients with sepsis and hemodynamic instability may be challenging in the ICU. Opioids and propofol can further exacerbate tissue infusion in septic shock by reducing cardiac contractility, increasing…
- Trial name
- NCT05839366
- Testing
- Esketamine, Saline, Remifentanil + propofol
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Mechanical Ventilation
Ultrasound of Diaphragmatic Musculature in Mechanically Ventilated Patients.
Muscle weakness and dysfunction are common problems in patients hospitalized in the intensive care unit. Respiratory muscle weakness during mechanical ventilation was recognized a state of muscular fatigue.
- Trial name
- NCT03281785
- Testing
- Pressure controlled mandatory ventilation mode (P-CMV), Pressure synchronized intermittent mandatory ventilation, Pressure support mode (PS)
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Mansoura University