Clinical trials: Mechanically Ventilated Patients
Mechanically Ventilated Patients, Lung Compliance
Effects of Ventilator Hyperinflation Versus Vibrocompression in Mechanically Ventilated Patients
The aim of the current study is to compare the effects of ventilator hyperinflation and vibrocompression on lung compliance in mechanically ventilated patients.
- Conditions
- Mechanically Ventilated Patients, Lung Compliance, Airway Clearance Impairment
- Trial name
- NCT06791798
- Testing
- Ventilator Hyperinflation, Vibrocompression, Traditional Chest Physical Therapy Program
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Cairo University
Critically Ill, Mechanically Ventilated
Treatment of Invasively Ventilated Adults With Early Activity and Mobilisation
The aim of this study is to evaluate the effect of early activity and mobilisation during prolonged IMV on the composite outcome "days alive and out of hospital to day 180".
- Trial name
- TEAM(III) (NCT03133377)
- Testing
- Early activity and mobilisation
- Where
- 49 sites in Australia, Germany and 3 more
- Volunteers
- 750 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Respiratory Failure, Circulatory Failure
Influence of Fluid Challenge on End-Expiratory Lung Impedance in Mechanically Ventilated Patients Monitored With Electrical Impedance Tomography
The study investigates the influence of a clinically indicated fluid challenge on end-expiratory lung impedance, assessed by electrical impedance tomography (EIT).
- Conditions
- Respiratory Failure, Circulatory Failure, Fluid Responsiveness, Fluid Overload
- Trial name
- NCT02992002
- Testing
- Fluid Challenge
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University Hospital Schleswig-Holstein
Septic Shock, Mechanical Ventilation Complication
Adjunctive Esketamine for Analgesia in Mechanically Ventilated Septic Shock Patients
Sedation and analgesia in patients with sepsis and hemodynamic instability may be challenging in the ICU. Opioids and propofol can further exacerbate tissue infusion in septic shock by reducing cardiac contractility, increasing…
- Trial name
- NCT05839366
- Testing
- Esketamine, Saline, Remifentanil + propofol
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Mechanical Ventilation
Ultrasound of Diaphragmatic Musculature in Mechanically Ventilated Patients.
Muscle weakness and dysfunction are common problems in patients hospitalized in the intensive care unit. Respiratory muscle weakness during mechanical ventilation was recognized a state of muscular fatigue.
- Trial name
- NCT03281785
- Testing
- Pressure controlled mandatory ventilation mode (P-CMV), Pressure synchronized intermittent mandatory ventilation, Pressure support mode (PS)
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Mansoura University
Intraabdominal Hypertension
Effect of Different Body Position on Intraabdominal Pressure in Mechanically Ventilated Patients
Measuring intraabdominal pressure in the semi-recumbent position and supine position.
- Trial name
- Ghada (NCT02644733)
- Testing
- head of bed elevation 30 degree, urinary catheter
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Critical Illness
Topical Application of Silver Nanoparticles and Oral Pathogens in Ill Patients
The purpose of this study is to determine whether oral topic silver nanoparticles are effective to reduce potential pathogen microbial loads in mechanical ventilation patients.
- Trial name
- NCT02761525
- Testing
- silver nanoparticles
- Volunteers
- 50 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Chronic Obstructive Pulmonary Disease(COPD)
Ventilator Asynchrony as a Predictor of Weaning Failure
Patient ventilator asynchrony is a common problem in mechanically ventilated patients .It is associated with adverse effects including increased work of breathing, patient discomfort, increased need for sedation, prolonged…
- Trial name
- NCT04735497
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Reham Mohammed Elmorshedy