Clinical trials: Medial Knee Osteoarthritis
Osteoarthritis, Knee, Avascular Necrosis of the Medial Femoral Condyle
Safety and Efficacy of the Oxford Cementless Partial Knee System
The objective of this clinical investigation is to evaluate the safety and effectiveness of the Oxford® Cementless Partial Knee System.
- Trial name
- NCT01473134
- Testing
- Oxford Cementless Partial Knee, Oxford Cemented Partial Knee
- Where
- 8 sites in United States
- Volunteers
- 320 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee, Osteoarthritis
The Three-dimensional Gait Analysis of Medial Knee Osteoarthritis
Static imaging has been commonly and clinically accepted to assess the severity of medial knee osteoarthritis (KOA), especially the radiography.
- Trial name
- NCT02878239
- Testing
- Steps 1, Steps 2
- Where
- China
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Osteoarthritis,Knee
Can 3D Kinematic Parameters Assess the Symptomatic and Functional Severity of KOA?
There is little study focusing on kinematic parameters in the assessment of the symptomatic and functional severity of knee osteoarthritis (KOA).
- Trial name
- NCT03011112
- Testing
- Observational procedure
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Knee Osteoarthritis
Effect of Knee Bracing on Improving Pain & Disability
The overall purpose of the proposed pilot study is to establish the feasibility of conducting a clinical trial by evaluating the preliminary effects of 8 weeks of knee bracing on physiological measures of self-reported pain and…
- Trial name
- NCT04044612
- Testing
- Medial Unloader Brace
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis, Knee
A Prospective Randomized Trial Using Roentgen Stereophotogrammetric Analysis of the Advance Medial Pivot Knee
The purpose of this study is to determine whether this particular knee replacement is better than those already on the market. By participation, it will further refine the design of future total knee replacements and perhaps…
- Trial name
- NCT00405470
- Testing
- Advance Medial Pivot Knee Arthroplasty
- Volunteers
- 80 people
- Sponsor
- Dalhousie University
Platelet Rich Plasma Injection, Ultrasonography
The Effects of Intra-articular and Peri-articular Platelet-rich Plasma (PRP) Injections ın Chronic Knee Osteoarthritis
The primary objective of this study is to evaluate and compare the effectiveness of ultrasound-guided combined intra-articular and peri-articular platelet-rich plasma (PRP) injections with intra-articular PRP injections alone in…
- Conditions
- Platelet Rich Plasma Injection, Ultrasonography, Gonarthrosis
- Trial name
- NCT07339137
- Testing
- Conservative Therapy, Intra-Articular PRP, Peri-Articular PRP
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara City Hospital Bilkent
Osteoarthritis
Evaluation of the Latella Knee Implant System for Medial Osteoarthritis Pain Reduction (Latella-2 Study)
The objective of the Latella-2 study is to demonstrate the safety and efficacy of the Latella Knee Implant System for the reduction of medial osteoarthritis knee pain.
- Trial name
- NCT02343705
- Testing
- Latella Knee Implant System
- Where
- 12 sites in Netherlands, Spain and 1 more
- Volunteers
- 67 people
- Sponsor
- Cotera, Inc.
Knee Osteoarthritis
Gait Modification and Knee Joint Load
This pilot study aims to assess the effect of a 6-week individualized gait retraining program on knee load and symptoms in persons with knee osteoarthritis (OA).
- Trial name
- NCT04946136
- Testing
- Gait modification
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Northwestern University
Knee Osteoarthritis
Stability of Contemporary Knee Arthroplasty
Total joint replacement is an efficacious treatment for osteoarthritis of hips and knees. Both total knee replacement (TKR) and total hip replacements (THR) have excellent implant survivorship.
- Trial name
- NCT02861794
- Testing
- Medacta International, GMK Sphere medially stabilized knee
- Where
- Norway
- Volunteers
- 44 people
- Sponsor
- Oslo University Hospital
Osteo Arthritis Knee
Clinical and Radiographic Outcomes of Medial Open-wedge High Tibial Osteotomy
Osteoarthritis is a common degenerative disorder of the articular cartilage . Risk factors include genetics, female sex, past trauma, advancing age, and obesity.
- Trial name
- NCT04036266
- Testing
- medial open wedge high tibial osteotomy
- Volunteers
- 60 people
- Sponsor
- Assiut University
Meniscus; Degeneration, Osteoarthritis, Knee
Treatment of the Medial Meniscus With the NUsurface(R) Meniscus Implant
This is a prospective, multi-center, open label, non-randomized study, evaluating the treating of medial meniscus deficiency with the NUsurface Meniscus Implant.
- Trial name
- NCT01712191
- Testing
- NUsurface Meniscus Implant
- Where
- 10 sites in Belgium, Germany and 4 more
- Volunteers
- 128 people
- Sponsor
- Phoenix Kinetics
Osteoarthritis, Knee, Osteonecrosis
Treatment of Medial Compartmental Osteoarthritis Grade 1-4 With TomoFix™ Small or Conservatively
The primary objective of this prospective multicenter study is to assess whether the functional outcome measured with the Knee Injury and Osteoarthritis Outcome Score (KOOS) for patients with medial unicompartmental…
- Trial name
- NCT01048710
- Testing
- No intervention
- Where
- Japan
- Volunteers
- 148 people
- Sponsor
- Synthes GmbH
Medial Knee Osteoarthritis
Effects of 3D-printed on Lower Extremity Biomechanics in Individuals With Knee Osteoarthritis
The purposes of this study are: (1) to determine the kinematics, kinetics, and muscle co-activation ratio of level walking and stair negotiation under three different conditions (shoes only, shoes embedded 3D printed insoles, and…
- Trial name
- NCT03843684
- Testing
- 3D-printed foot orthoses, 5 degrees lateral wedge insoles
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- National Yang Ming Chiao Tung University
Knee Osteoarthritis
Effects of Ultrasound Therapy on Cartilage Healing in Patients With Knee Osteoarthritis
The purpose of this study is to determine the effects of low intensity ultrasound therapy over the cartilage morphology (thickness and volume) of patients with mild or moderate knee osteoarthritis.
- Trial name
- NCT00931749
- Testing
- Low intensity pulsed ultrasound therapy
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- McMaster University
Knee Osteoarthritis, Degenerative Joint Disease of the Knee
Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomized Insert Types
This study aims to evaluate patient outcomes following robotic-assisted total knee arthroplasty using the VELYS system. Patients undergoing surgery will receive either kinematic alignment or functional alignment as determined by…
- Trial name
- VELYS RCT (NCT07533188)
- Testing
- Medial Stabilized Insert, Cruciate Retaining Insert
- Where
- Singapore
- Volunteers
- 240 people
- Sponsor
- Singapore General Hospital
Arthritis Knee
Preoperative Radiographic Evaluation of Medial Tibiofemoral Knee Osteoarthritis
Observational study.
- Trial name
- RX-FTI (NCT03704558)
- Sponsor
- Rennes University Hospital
Osteoarthritis, Knee
Clinical Outcomes of MP Persona vs. Persona Knee-PS
Knee osteoarthritis (OA) is a highly prevalent condition that results in substantial pain and loss of function. The end stage treatment for knee OA is total knee arthroplasty (TKA), a common and safe procedure typically performed…
- Trial name
- MP-Persona (NCT03681977)
- Testing
- Zimmer MP Persona, Zimmer Persona Knee-PS
- Where
- 3 sites in Canada
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Osteoarthritis, Knee
Personalised HTO Versus Generic HTO Virtual Clinical Trial
High Tibial Osteotomy (HTO) is an alternative to knee replacement in suitable patients with early knee osteoarthritis (OA), it is particularly suited to patients with single compart disease who otherwise would be suitable for…
- Trial name
- NCT03419598
- Testing
- Opening wedge high tibial osteotomy, Personalised subject specific custom HTO plate, Generic HTO plate
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Bath
Medial Compartment Osteoarthritis, Genu Varum
TO Plate Fixation vs. External Fixator Comparison (HTO Plate vs. ExFix Study)
This study aims to compare the efficacy, accuracy, and functional outcomes of two different surgical stabilization techniques for medial opening wedge high tibial osteotomy (HTO) in patients with varus deformity and medial…
- Conditions
- Medial Compartment Osteoarthritis, Genu Varum, Varus Deformity, High Tibial Osteotomy
- Trial name
- NCT07220434
- Testing
- Medial HTO Locking Plate, Self-Adjusting HTO External Fixator
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Muhammed Cagatay Engin
Knee Osteoarthritis
Comparison of Proprioception for HTO (High Tibial Osteotomy) and UKA (Unicompartmantal Knee Arthroplasty)
Osteoarthritis of the knee (KOA), a common degenerative joint disease, affects a significant part of the world's population. Although it can hold all the compartments in the knee joint, isolated medial compartment involvement has…
- Trial name
- NCT05993637
- Testing
- Examination of propriception
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa