Clinical trials: Mediation, active
Breast Feeding, Exclusive
Evaluation of a Health Mediation Program in the Maternity Ward.
The first months of life are considered a critical period that has a lasting impact on a child's future health. Breastfeeding is one of the fundamental factors contributing to healthy growth in children.
- Trial name
- MédiMAT (NCT07806942)
- Testing
- postpartum breastfeeding support from a health mediator, routine health care without health mediation
- Where
- French Guiana
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Type 2 Diabetes Mellitus, Diabetic Retinopathy (DR)
Glycemic Velocity and Early Retinal Microvascular Change With GLP-1RA Versus SGLT2i Initiation in Type 2 Diabetes (GLIDE)
The GLIDE study looks at how the small blood vessels of the eye respond during the first months of a new diabetes medicine. Two widely used classes of glucose-lowering drugs, GLP-1 receptor agonists and SGLT2 inhibitors, are…
- Trial name
- GLIDE (NCT07723820)
- Testing
- GLP-1 Receptor Agonists, SGLT2 inhibitor
- Where
- Thailand
- Volunteers
- 126 people
- Sponsor
- Thammasat University Hospital
Violence, Gender-Based, Violence, Domestic
Responsible Engaged and Loving (REAL) Fathers Intervention Evaluation
The goal of this stepped-wedge cluster randomized control trial is to assess whether a Ugandan community-based intervention for young fathers (ages 18-25 years) of children ages 0-3 years impacts fathers' knowledge, attitudes…
- Conditions
- Violence, Gender-Based, Violence, Domestic, Violence, Sexual, Violence, Physical
- Trial name
- NCT06100679
- Testing
- Responsible Engaged and Loving (REAL) Fathers Initiative
- Where
- 4 sites in Uganda
- Volunteers
- 4,728 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Avoidant/Restrictive Food Intake Disorder (ARFID)
Cognitive-behavioral Therapy vs. Nutrition Counseling for Avoidant/Restrictive Food Intake Disorder Part II
This study is a randomized controlled trial assessing the efficacy of cognitive- behavioral therapy (CBT-AR) and nutrition counseling for avoidant/restrictive food intake disorder (ARFID) for children and adolescents (ages 10-18…
- Trial name
- COUNTERACT-2 (NCT07641205)
- Testing
- Cognitive-Behavioral Therapy for Avoidance Restrictive Food Intake Disorder (CBT-AR), Nutrition Counseling for Avoidant/Restrictive Food Intake Disorder
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Aggression, Critical Care Staff
Intensive Care Unit Conflict Mediation Study
To evaluate the impact of a structured, multidisciplinary conflict management program incorporating an interprofessional Singular Care Plan *PAS* Committee and a Conflict Mediation Team on the incidence and severity of conflicts…
- Conditions
- Aggression, Critical Care Staff, Workplace Violence
- Trial name
- "GIRAFFE" (NCT07621874)
- Testing
- SEM DESTINO
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Condomless Sex, Sexual Assault
Evaluating a Digital Intervention to Improve Adolescent Condom Use and Communication
The purpose of this study is to test the effectiveness, likability, and implementation potential of PACT, an adapted digital program to teach non-heterosexual adolescent boys about sexual consent and condom negotiation in a…
- Trial name
- NCT06878755
- Testing
- Promoting Assertive Communication among Teens (PACT), Healthy Minds
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Schizophrenia, Bipolar Disorder
Emotional Eating, Sleep Quality, Mental State and Metabolic Syndrome
In predominantly medication-naïve schizophrenic patients, those exhibiting partial metabolic disorders have significantly worse sleep quality and sleep onset time; poor sleep predicted metabolic dysregulation even after…
- Conditions
- Schizophrenia, Bipolar Disorder, Psychiatric Issue, Metabolic Syndrome
- Trial name
- NCT07411222
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Abant Izzet Baysal University
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Mediation
Study of the Conditions of the Effects of Health Mediation on Underserved Population
The investigators are conducting a longitudinal mixed-method intervention study with a multi-center, multi-case explanatory sequential design.
- Trial name
- ECEMSo (NCT06180746)
- Testing
- Knowledge mobilization to facilitate the structuring of health mediation
- Where
- France
- Volunteers
- 1,041 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Chronic Cancer-related Pain
An N-of-1 Trial of an Internet-delivered CBT Program Based on the Psychological Flexibility Model of Chronic Pain for Cancer-related Difficulties
Chronic pain is a commonly occurring complication of cancer and can have negatively impact day-to-day functioning and well-being. The recommended treatment for all forms of chronic pain is cognitive behavioral therapy (CBT).
- Trial name
- NCT06749964
- Testing
- Internet-delivered, therapist-assisted, pain-focused CBT based on the psychological flexibility model for chronic pain
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Lund University
Acute Hypoxemic Respiratory Failure
Is Hypoxemia Driving Outcome in Acute Hypoxemic Respiratory Failure? (HOMELAND Study)
Acute hypoxemic respiratory failure (AHRF) is the most common cause of admission in the intensive care units (UCIs) worldwide. The investigators will assess the value of mediation analysis (a statistical method to understand the…
- Trial name
- HOMELAND (NCT07708506)
- Testing
- mediation analysis
- Where
- 18 sites in Spain, United Kingdom
- Volunteers
- 1,241 people
- Sponsor
- Jesus Villar
Depression, Stress
Internet Based Psychological Support
The investigators have developed interactive, multimedia-intensive, computer-based treatment programs that include depression (Problem-Solving Therapy), stress management, and conflict management.
- Conditions
- Depression, Stress, Conflict Resolution
- Trial name
- NCT02726061
- Testing
- Internet-based psychological support
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Frailty, Frailty at Older Adults
Implementation of the Personalized Care Plan (PCP) Proposed at the End of Step 2 of the ICOPE Program
The ICOPE (Integrated Care for the Elderly) program is based on an integrated approach including a personalized care plan (PCP).
- Trial name
- INEPPS (NCT07379099)
- Where
- France
- Volunteers
- 600 people
- Sponsor
- MSPU de Pins-Justaret
Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Injury
Stair Biomechanics and Vibration Study After ACLR
This study examines how people who have had anterior cruciate ligament reconstruction (ACLR) move their legs during walking and stair negotiation, and whether a single session of vibration changes how they ascend and descend…
- Trial name
- NCT07922785
- Testing
- Whole-body Vibration, Local Muscle Vibraton, Control condition
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Emergence Delirium
Frontal Alpha Asymmetry and Pediatric Emergence Delirium
This study aimed to investigate whether the association between the preoperative anxiety level and emergence delirium involves EEG frontal alpha asymmetry in pediatric patients undergoing ophthalmic surgery under general…
- Trial name
- NCT05800639
- Testing
- Ophthalmic surgery, General anesthesia
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Gangnam Severance Hospital
Alzheimer's Disease (AD), Dementia
Negotiation Training for Family Caregivers of People With Alzheimer's Disease
Family caregivers of people living with Alzheimer's disease and related dementias often experience conflicts and communication challenges when coordinating care, making decisions, and interacting with family members and…
- Conditions
- Alzheimer's Disease (AD), Dementia, Cognitive Impairment
- Trial name
- NCT07859540
- Testing
- NegotiAge, PlanYourLifespan
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Epilepsy
Impact of Canine Mediation Practice in Psychomotor Therapy on Improving the Quality of Life in Adult Epileptic Patients.
In addition to the search for new pharmaceutical or surgical solutions that could improve the therapeutic management of epileptic individuals, it is interesting to ask whether other complementary approaches, such as canine…
- Trial name
- MCP-Epi (NCT06898749)
- Testing
- canine mediation, standard psychomotor therapy
- Where
- 2 sites in France
- Volunteers
- 76 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Equine-assisted Therapy, Addiction
The Impact of Equine-Assisted Therapy on Mental Health and Addictive Behaviors in Patients Receiving Addiction Treatment
Addiction is a major public health issue. According to the World Health Organization (2024), approximately 400 million people worldwide suffer from alcohol- or drug-related disorders, resulting in nearly 3.2 million deaths per…
- Conditions
- Equine-assisted Therapy, Addiction, Recidivism, Addictive Behaviors
- Trial name
- EQUI-ADDICT (NCT07495839)
- Testing
- Equine mediation
- Volunteers
- 22 people
- Sponsor
- Hopital La Musse
Mediation of 5G Effects on Sleep
A Causal Role for Voltage-gated Cav1.2 Calcium Channels in Mediating 5G FR1 Effects on Sleep-associated Brain Health in Humans
Electromagnetic fields (EMFs) generated by the use of 5G technology influence certain sleep characteristics, especially in individuals carrying a specific genetic variant of a protein in the brain that regulates the activity of…
- Trial name
- 5G Cav12 Sleep (NCT06998368)
- Testing
- Nimodipine Capsules, 5G RF-EMF
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hans-Peter Landolt
Autism Spectrum Disorder
Emotional Skills Training with Social Robot
Autism is a neurodevelopmental disorder that involves difficulties especially in the sphere of social interaction, social communication, and restricted and stereotyped behavior patterns.
- Trial name
- NCT06179953
- Testing
- NAO intervention, Traditional intervention
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica