Clinical trials: Medical Abortion
Pregnancy
Simplified Medical Abortion in Rural India
It is estimated that around 50 000 women die every year due to consequences of unsafe abortion (Singh et al, 2009). A majority of these deaths occur in low-income countries where access to safe abortion care is limited.
- Trial name
- NCT01827995
- Testing
- Self assessment, Routine assessment
- Where
- India
- Volunteers
- 731 people
- Sponsor
- Karolinska Institutet
Early Miscarriage
Identification of Histories of Pregnancy Termination, Particularly Early Miscarriage, in General Medical Records
Early miscarriage (EM) is defined as the spontaneous expulsion of an intrauterine pregnancy of less than 14 weeks' duration. Early miscarriage is a very common complication, affecting more than 10% of pregnancies.
- Trial name
- NCT07406776
- Where
- France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Medical Abortion
Treatment Regimens for Mifegyne and Cytotec
The purpose of this study is to test two regimens of mifegyne and cytotec for medical abortion. The investigators hypothesize that administration of both medications during one hospital visit will not compromise effectiveness.
- Trial name
- NCT00920465
- Testing
- mifegyne and cytotec
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Western Galilee Hospital-Nahariya
Termination of Pregnancy (TOP)
Interest of Cervical Dilators in Second Trimester Termination of Pregnancy
The purpose of this study is to evaluate whether the use of cervical dilators for cervical ripening in case of second trimester medical termination of pregnancy (TOP) is effective to reduce duration of labor.
- Trial name
- DILATOP (NCT03194230)
- Testing
- With cervical dilatator
- Where
- France
- Volunteers
- 355 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abortion-Related Disorders
Pain Assessment in MToP Up to 7 WA (during 5h After Misoprostol Intake)
In 2016, medical termination of pregnancy represent 64% of total abortions in France. Thus, it is a frequent act involving a large majority of women and a health-care public subject.
- Trial name
- DoMy (NCT03659045)
- Testing
- scale of pain
- Where
- 8 sites in France
- Volunteers
- 320 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Abortion Failure
Non-surgical Alternatives to Treatment of Failed Medical Abortion
The primary outcome of this study is to compare the effectiveness of a second complete course of 200 mg mifepristone and 800 mcg misoprostol for ongoing pregnancy following mifepristone-misoprostol medical abortion.
- Trial name
- NCT02704481
- Testing
- Mifepristone, Misoprostol
- Where
- 14 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical; Abortion, Fetus
Comparison of Telephone Follow-up With In-person Follow-up After Medical Abortion
Background: Medical abortions in Canada are provided using a standard regimen of methotrexate and misoprostol. After these medications are administered, patients are most commonly checked for termination of the pregnancy with an…
- Trial name
- NCT01943279
- Testing
- Remote Follow-up (RFU), Standard Follow-up (SFU)
- Where
- 2 sites in Canada
- Volunteers
- 139 people
- Sponsor
- Women's College Hospital
Unwanted Pregnancies
Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion
Background: In most countries in which abortion is legal, medical abortions are induced with mifepristone and misoprostol. Since mifepristone is expensive and unavailable in many countries, it is important to find other regimens.
- Trial name
- NCT00129506
- Testing
- methotrexate + misoprostol, misoprostol
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Wiebe, Ellen, M.D.
Termination of Pregnancy Second Trimester
Misoprostol for Second Trimester Termination of Pregnancy
To compare the efficacy of two different dose regimens of misoprostol administered vaginally in combination with mifepristone in second trimester termination of (non)viable pregnancy.
- Trial name
- MIMIS (NCT00945997)
- Testing
- misoprostol
- Where
- Netherlands
- Volunteers
- 176 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Abortifacient Agents, Nonsteroidal, Abortion, Incomplete
Misoprostol for Non-Viable Pregnancies
The purpose of this study is to examine the effectiveness of Misoprostol (Cytotec; GD Searle and Co., Chicago, IL) for the management of non-viable first trimester pregnancies.
- Conditions
- Abortifacient Agents, Nonsteroidal, Abortion, Incomplete, Misoprostol, Pregnancy
- Trial name
- NCT00426491
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Medical Abortion
De-Medicalizing Mifepristone Medical Abortion
This study will investigate the possibility that medical abortion using mifepristone and misoprostol - a safe, proven therapy for terminating early first trimester pregnancy - can be administered in a manner that is simpler and…
- Trial name
- NCT00120224
- Where
- 3 sites in United States
- Volunteers
- 4,410 people
- Sponsor
- Gynuity Health Projects
Spontaneous Abortion, Fetal Death
Environmental Factors and Embryonic Development Project
The Environmental Factors and Embryonic Development Project was set up to investigate environmental exposures and behavioral factors responsible for embryonic dysplasia and gestational complications in pregnant women.
- Conditions
- Spontaneous Abortion, Fetal Death, Stillbirth, Birth Defects
- Trial name
- EFED (NCT04182503)
- Testing
- No intervention
- Where
- 19 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Missed Abortion
Sublingual Versus Vaginal Misoprostol In Medical Treatment of First Trimestric Missed Miscarriage
The aim of this work is to compare the effectiveness of vaginal versus sub-lingual misoprostol for medical treatment of first trimester missed miscarriage.
- Trial name
- NCT02686840
- Testing
- sublingual misoprostol, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Contraception
Study of Immediate Start of Progestin Contraceptives in Medical Abortion
This study will compare immediate to post-abortion start of two progestin-based contraceptives (DMPA and etonorgestrel implants) among women having first trimester medical abortion who wish to use that method for post-abortion…
- Trial name
- Quickstart (NCT01902485)
- Testing
- Timing of Contraceptive Initiation in Medical Abortion
- Where
- 8 sites in United States, Mexico
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects