Clinical trials: Medical Cannabis
Chronic Pain
Safety and Efficacy of Medical Cannabis Oil in the Treatment of Patients with Chronic Pain
Seeking for effective therapeutic strategies, the investigators are proposing to test the effectiveness of different formulations of medical cannabis oil to alleviate chronic pain, which was partially relieved with conventional…
- Trial name
- NCT03337503
- Testing
- THC and CDB in a 1 to 1 ratio, Experimental: THC and CBD in a 1 to 2 ratio, High CBD with trace THC oil
- Where
- Canada
- Volunteers
- 161 people
- Sponsor
- Santé Cannabis
Inflammatory Bowel Diseases, Neuropathic Pain
GI Medical Cannabis Study on IBD
Create a registry that will described the natural history and landscape of medical cannabis product use in patients with chronic abdominal pain or inflammatory bowel disease.
- Trial name
- GIMEDCAN (NCT03886532)
- Testing
- Medical Marijuana
- Sponsor
- Children's Hospital of Philadelphia
Pain, Nausea
Cannabis For Cancer-Related Symptoms
Clinical evidence is urgently needed to be able to advise patients on which cannabis-based products to take, or to avoid, in managing cancer-related symptoms.
- Conditions
- Pain, Nausea, Anxiety, Sleep Disturbance
- Trial name
- CAFCARS (NCT03948074)
- Testing
- Cannabis
- Where
- 8 sites in Canada
- Volunteers
- 91 people
- Sponsor
- Pippa Hawley
Pain
Safety and Effects on Responses to Stress and Pain of Natural Medical Marijuana Products
This proposal aims to systematically examine the safety and pharmacokinetic/pharmacodynamic profile and the physiologic, neuroendocrine and behavioral stress and pain responses to acute single doses and repeated dosing of oral…
- Trial name
- NCT04226690
- Testing
- Active CBD/THC Dose 1, Active CBD/THC Dose 2
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Autism Spectrum Disorder
Evaluating the Efficacy of NTI164 in Young People With Autism Spectrum Disorder
This is an 18 to 54 week study assessing the efficacy of Full-Spectrum Medicinal Cannabis Plant Extract 0.08% THC (NTI164) on the severity of autism spectrum disorder in young people.
- Trial name
- NCT05626959
- Testing
- NTI164
- Where
- Australia
- Volunteers
- 54 people
- Sponsor
- Fenix Innovation Group
Cannabis Dependence
Gabapentin Treatment of Cannabis Dependence
This is a study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.
- Trial name
- NCT00395044
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Scripps Research Institute
Medical Abortion, Pain
Cannabinoids for Pain Control During Medical Abortion
The objective of this study is to determine if a synthetic cannabis derivative, dronabinol, in addition to ibuprofen, decreases maximum pain scores compared to ibuprofen and placebo in women undergoing medical abortion.
- Trial name
- NCT03604341
- Testing
- Dronabinol 5mg Cap
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Oregon Health and Science University
Major Depressive Disorder, Generalized Anxiety Disorder
Cohort Study on Medical Students' Mental Health
The main objective of this study is to identify risk factors for depression among medical students by comparing them to students who completed their first year but did not enter the medical program (students not accepted into the…
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Suicidal Ideation, Alcoholism
- Trial name
- OSMOSE (NCT07305701)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Chronic Pain
PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product
This study is a clinical trial of a high-cannabidiol (CBD) sublingual product compared to placebo for 9 weeks in patients with chronic pain conditions.
- Trial name
- NCT03984565
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Staci Gruber, Ph.D.
Marijuana Dependence
Marijuana Treatment Project 4
Marijuana is the most commonly used illicit drug in the US, but treatment for marijuana dependence is not fully effective. In the current proposal we are exploring the idea that more tailored teaching of coping skills may result…
- Trial name
- MTP4 (NCT02030665)
- Testing
- Contingency Management, Individualized Assessment & Treatment, Cognitive-Behavioral Treatment
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- UConn Health
Medical Cannabis
Evaluation of Interprofessional Relations Between Primary Care and Hospital Centers in the Experimentation of Medical Cannabis in France Carried Out by the ANSM (ECIPCanna)
An observational study to explore inter-professional relations and perceptions around the experimentation of medical cannabis, conducted by the French National Agency for Safety and Health.
- Trial name
- ECIPCanna (NCT06597097)
- Where
- France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Brest
Chronic Pain Patients, Medical Cannabis Users
Medical Cannabis and Behavior
This study will assess cognition, neural function, and drug exposure in chronic pain patients who have been prescribed medical cannabis and will differentiate outcomes based on use of specific CBD-dominant versus THC-dominant…
- Trial name
- NCT06808048
- Testing
- Cognitive testing, Task-based fMRI measure of face-name and verbal learning
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Minnesota
Autistic Disorder
A Trial to Assess the Efficacy and Safety of Medical Grade Cannabis in Children Diagnosed With Autism Spectrum Disorder
This single center, double-blinded, randomized, placebo-controlled crossover trial will assess the efficacy and safety of extraction of cannabis flowers dissolved in olive oil (30% CBD and 1.5% Δ9-THC) vs.
- Trial name
- NCT05413187
- Testing
- Medical Grade Cannabis oil
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- TO Pharmaceuticals
Cannabis Use, Healthy Subjects
Pharmacokinetics and Pharmacological Effects of a Standardized Cannabis Preparation
The purposes of the study are 1) to know the concentrations of Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD) and other cannabinoids in blood, urine, oral fluid and sweat after the experimental administration of a standardized…
- Trial name
- CANNMED (NCT04841993)
- Testing
- Cannabis decoction, Cannabis oil, Vaporized cannabis
- Where
- Spain
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Germans Trias i Pujol Hospital
Opioid Use, Marijuana
MEMO-Medical Marijuana and Opioids Study
The study will examine how medical cannabis use affects opioid analgesic use over time, with particular attention to THC/CBD content, HIV outcomes, and severe adverse events.
- Conditions
- Opioid Use, Marijuana, Chronic Pain, HIV/AIDS
- Trial name
- NCT03268551
- Where
- 2 sites in United States
- Volunteers
- 257 people
- Sponsor
- Albert Einstein College of Medicine
HIV Infections, Neuropathic Pain
Pain Inflammation and Cannabis in HIV
This study will examine how medical cannabis use affects neuropathic pain, inflammation and adverse events in people living with HIV (PLWH) with neuropathic pain.
- Conditions
- HIV Infections, Neuropathic Pain, Cannabis
- Trial name
- PITCH-E (NCT05554146)
- Testing
- Receipt of Coupon for High THC Soft-Gel Capsule, Receipt of Coupon for Equal THC and CBD Soft-Gel Capsule, Receipt of Coupon for High CBD Soft-Gel Capsule
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Montefiore Medical Center
PANS Pediatric Acute-Onset Neuropsychiatric Syndrome
Investigating The Effects Of Full-Spectrum Medicinal Cannabis Plant Extract 0.08% THC (NTI164) On Paediatric Acute-onset Neuropsychiatric Syndrome (PANS)
This study investigates the effectiveness of a medicinal cannabis extract (NTI164) with 0.08% THC in treating children with pediatric acute-onset neuropsychiatric syndrome (PANS) over a period of 18 to 54 weeks.
- Trial name
- CannaPANS (NCT06621888)
- Testing
- NTI164
- Where
- 2 sites in Australia
- Volunteers
- 18 people
- Sponsor
- Fenix Innovation Group
Chronic Pain, Fibromyalgia
Full-Spectrum Cannabis Extract for Chronic Pain and Bone Health Biomarkers in Women
Chronic pain disproportionately affects women and may coexist with impaired bone health, particularly during midlife and after menopause.
- Conditions
- Chronic Pain, Fibromyalgia, Osteoporosis, Orofacial Pain
- Trial name
- ORION (NCT07783295)
- Testing
- Full-Spectrum Cannabis Extract 5:1 (CBD:THC)
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Associação Pan-Americana Multidisciplinar de Endocanabinologia
Opioid Use, Pain
Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain…
- Conditions
- Opioid Use, Pain, Marijuana Use
- Trial name
- NCT04827992
- Testing
- Cannabis, Prescription Opioid Taper Support (POTS)
- Where
- 3 sites in United States
- Volunteers
- 87 people
- Sponsor
- Massachusetts General Hospital
Opioid Use, Marijuana
Does Medical Cannabis Reduce Opioid Use in Adults With Pain
The study will examine how medical cannabis use affects opioid analgesic use. This landmark study will be among the first to examine the effect of medical cannabis with different THC/CBD (Tetrahydrocannibinol/Cannabidiol) content…
- Conditions
- Opioid Use, Marijuana, Chronic Pain
- Trial name
- ReLeaf-E (NCT04308148)
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- Albert Einstein College of Medicine