Clinical trials: Medical Care
Chronic Kidney Disease, Type 2 Diabetes
RAndomized EHR-based Prescribing to Improve Disease-modifying Therapies for Cardio-Kidney-Metabolic Care (RAPID-CKM)
The goal of this pragmatic randomized clinical trial is to determine whether an Epic-based clinician notification increases initiation of guideline-directed cardio-kidney-metabolic (CKM) therapies in adults with type 2 diabetes…
- Trial name
- NCT07605390
- Testing
- Epic-Based Clinician Notification, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- Baylor Research Institute
All International Classification of Primary Care 2 Diagnoses
Effect Evaluation of Independent Medical Evaluation (IME) in Norway
A randomized controlled trial comparing independent medical evaluation (IME) to treatment as usual (TAU). Participants will be individuals reaching six months uninterrupted sickness absence.
- Trial name
- NIME (NCT02524392)
- Testing
- Independent medical evaluation
- Where
- Norway
- Volunteers
- 7,642 people
- Sponsor
- NORCE Norwegian Research Centre AS
Stress, Pupillometry
Stress Evaluation and Management Using High Fidelity Simulation in Medical Education
The goal of this interventional study is to collect clinical and neurophysiological information to determine whether high-fidelity simulation can serve as a stress-inducing stimulus in a population of healthy residents (Emergency…
- Conditions
- Stress, Pupillometry, High Fidelity Simulation Training, Resident Education
- Trial name
- STRATAGEM (NCT06916949)
- Testing
- Electrocardiogram, Pupillometry, Electroencephalogram
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Atrial Fibrillation
Magnesium Sulphate for Treatment of New Onset Atrial Fibrillation in Medical Intensive Care Unit Patient
The purpose of this study is to determine the efficacy of Magnesium sulphate for the rate and rhythm control of the new onset (within 48 hours) atrial fibrillation in the hemodynamically unstable patients, admitted in the medical…
- Trial name
- EMSAF (NCT01049464)
- Testing
- Magnesium sulphate
- Where
- Thailand
- Volunteers
- 128 people
- Sponsor
- Mahidol University
Training, Education
Competencies Required by Anesthesiologists Managing Critically Ill Patients
Critical Care Medicine (CCM) has emerged as an independent specialty over the last few decades. Anesthesiologists being perioperative physicians, often practice CCM full time or part-time.
- Conditions
- Training, Education, Competence
- Trial name
- NCT05007704
- Testing
- Global Experts Consensus opinion using Delphi Methodology
- Where
- India
- Volunteers
- 1,155 people
- Sponsor
- Prashant Nasa
Initial Radiological Diagnosis Eligible for Tumor Resection, Initial Radiological Diagnosis Compatible With Newly Diagnosed Glioblastoma (IDH Wild-type)
Innovative SonoCloud-9 Device for Blood Brain Barrier Opening in First Line Temozolomide Glioblastoma Patients.
Glioblastoma (GBM) is an aggressive cancer with a progression-free survival (PFS) of 7 months and an overall survival (OS) of 15 months. Many therapeutic approaches have failed to improve the prognosis of patients to date.
- Conditions
- Initial Radiological Diagnosis Eligible for Tumor Resection, Initial Radiological Diagnosis Compatible With Newly Diagnosed Glioblastoma (IDH Wild-type), Eligible for the Standard of Care Including Concurrent Temoradiation and Adjuvant Temozolomide
- Trial name
- SonoFIRST (NCT04614493)
- Testing
- SonoCloud-9 (SC9) device, Temozolomide according Stupp protocol
- Where
- 7 sites in Belgium, France and 1 more
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cutaneous Melanoma
MelaMEd Online Training for General Practitioners to Improve Melanoma Detection and Management
The goal of this trial was to learn whether the MelaMEd online training program could improve doctors' skills in the early detection and management of melanoma, the most aggressive type of skin cancer.
- Trial name
- MelaMEd (NCT07757386)
- Testing
- MelaMEd Online Training Program
- Where
- 10 sites in Italy
- Volunteers
- 1,531 people, healthy volunteers welcome
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA)
FEMART-1 Pilot Study
The FEMART-1 Pilot Study is focused on evaluating the feasibility, safety, and procedural timing of prehospital femoral arterial sheath placement in patients with non-traumatic out-of-hospital cardiac arrest (OHCA), both during…
- Conditions
- Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA), Cardiogenic Shock Acute
- Trial name
- FEMART-1 (NCT07596446)
- Testing
- Prehospital Ultrasound-Guided Femoral Arterial Sheath Placement
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Emergency Medical Service, Prague
Depression Chronic, Depression and Quality of Life
Remote Medical Monitoring of Patients With Depression
The goal of this clinical trial is to learn if ThIA Suivi, a digital tool for remote monitoring of patients, can improve the care of adults with depression who are followed by a psychiatrist.
- Conditions
- Depression Chronic, Depression and Quality of Life, Depression, Major Depressive Episode
- Trial name
- TELEMED-DEP (NCT07878754)
- Testing
- Use of ThIA Medical Device
- Where
- 3 sites in France
- Volunteers
- 608 people
- Sponsor
- ThIA Santé Mentale
Medical Oncology, Cardiology
Results From a Health System-wide Implementation of a Quality of Life Questionnaire
The purpose of this retrospective chart review pilot study is to research the results and scores of the QOL questionnaire implemented across Allina Health clinics.
- Conditions
- Medical Oncology, Cardiology, Integrative Medicine, Physical and Rehabilitation Medicine
- Trial name
- NCT02906423
- Testing
- PROMIS-10 questionnaire
- Where
- United States
- Volunteers
- 43,000 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Diabetes
Bamberg Diabetes Transitional Care Pilot Study
Bamberg County residents who has been diagnosed with or is at high risk for diabetes, may be eligible for a clinical research study to improve diabetes self-management and decrease hospital re-admissions.
- Trial name
- NCT02560090
- Testing
- Surveys, Telephonic Nurse Intervention, In-person Community Health Worker
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Medical University of South Carolina
Sarcoma
Burden and Medical Care of Sarcoma in Germany
The main objective of the study is to assess the treatment situation of sarcoma patients in Germany and to investigate their potential influence on Quality of Life (and other Patient Reported Outcomes) of the affected persons.
- Trial name
- PROSa (NCT03521531)
- Where
- Germany
- Volunteers
- 1,309 people
- Sponsor
- Technische Universität Dresden
Sleep Deprivation, Depression
Work Hour Reductions, Medical Errors, and Intern Well-Being at Providence St. Vincent Medical Center Intensive Care Unit
The purpose of this study is to determine whether reducing intern work hours and eliminating extended shifts in the intensive care unit will reduce prescribing errors and improve intern well-being.
- Trial name
- NCT00996320
- Testing
- Reduced work hour schedule
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Providence Health & Services
Average Length of Stay, Surgery
Assessment of the Feasibility and Organisational Impact of a Care Pathway Incorporating the MultiSense® Medical Device for Post-operative Home Monitoring of Elderly Patients.
Assessing the clinical and organisational impact of a home-based post-operative monitoring strategy incorporating the MultiSense® device involving 80 patients aged 65 years and over who have undergone major surgery.
- Trial name
- IMPACT - MS (NCT07514286)
- Testing
- Monitoring by MultiSense
- Where
- 4 sites in France
- Volunteers
- 80 people
- Sponsor
- Rhythm Diagnostic Systems
Hematologic Neoplasms
Therapeutic Virtual Reality : Impact on the Management of Pain and Anxiety Related to Hematology Care (REVEH)
The management of hematological malignancies justifies the completion of a complete assessment before the start of treatment. This assessment includes imaging tests (computed tomography, position emission tomography, cavitary…
- Trial name
- REVEH (NCT03483194)
- Testing
- Virtual Reality, Kalinox
- Where
- 5 sites in France
- Volunteers
- 126 people
- Sponsor
- Weprom
Dermatitis, Atopic
Curing Atopic Dermatits in Children With a Commerical Medical Device and Maintaining Healthy Skin by Using a New Cosmetic Product
1. Curing mild atopic dermatis in children with a commerical medical device (Bepanthen Itch Relief Cream). 2. Maintaining healthy skin by using a new cosmetic Bepanthen product or a commercially available cosmetic product
- Trial name
- NCT02615561
- Testing
- Bepanthen Itch Relief Cream: Phoenix 2 (Bepanthen Sensiderm, BAY207543), New cosmetic Bepanthen product: Pumpkin (BAY207543), Stelatopia (cosmetic comparator)
- Where
- 14 sites in Germany
- Volunteers
- 136 people
- Sponsor
- Bayer
Advanced Cancer
Web-Based Advance Care Planning for Patients With Advanced Cancer
The goal of this clinical trial is to determine whether a web-based advance care planning (ACP) intervention can reduce preferences for aggressive life-sustaining treatments among patients with advanced cancer.
- Trial name
- NCT07712237
- Testing
- Web-Based Advance Care Planning Program, Patient Right to Autonomy Act Leaflet
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Analgesia
Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU)
This study will be a multicentre randomized, open-label, phase IIIb study. This study will evaluate two different techniques of sedation: an analgesia based regimen with remifentanil versus a conventional sedation based regimen…
- Trial name
- NCT00436345
- Testing
- Remifentanil, Propofol
- Where
- 6 sites in Italy
- Volunteers
- 39 people
- Sponsor
- GlaxoSmithKline
Cardiovascular Diseases, Heart Failure
A Survey to Assess Effects of Covid-19 on Cardiovascular Patients
The design included 152 patients with confirmed heart failure (HF) evaluated in two different periods of time: a baseline before the outbreak, and other during the outbreak of which 76 patients were randomized in each group.
- Trial name
- NCT04508920
- Testing
- Symptomatology, Treatment. daily Activities and Anxiety for Cardiovascular patients Survey (STRATA)
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Centro en Insuficiencia Cardiaca, Mexico
Coronavirus, Nurse's Role
Perceived Stress Among ICU Medical Staff During COVID-19 Crisis
The objective of this study is to compare psychological distress and needs of nurses in ICU before and during coronavirus pandemic.
- Conditions
- Coronavirus, Nurse's Role, Professional Stress
- Trial name
- ICUcovid (NCT04604769)
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Liege