Clinical trials: Medical Complications
Bacterial Vaginosis | Vaginal | Microbiology
Efficacy and Safety of D005 Vaginal Mousse on Bacterial Vaginosis
This is a randomised, double-blind clinical investigation to evaluate the efficacy and safety of D005 vaginal mousse compared to placebo, in women with bacterial vaginosis.
- Trial name
- NCT04489290
- Testing
- D005 Vaginal Mousse
- Where
- 9 sites in Sweden, United Kingdom
- Volunteers
- 83 people
- Sponsor
- PepTonic Medical AB
Stress Urinary Incontinence
An Investigation With an Intra-vaginal Device for Stress Urinary Incontinence
This is a prospective, randomized, controlled, two-armed multi-center pre-market trial. Nighty-six (96) subjects will be recruited at sites in Sweden.
- Trial name
- NCT03186651
- Testing
- TVS
- Where
- 4 sites in Sweden
- Volunteers
- 97 people
- Sponsor
- Invent Medic Sweden AB
Urinary Calculus
A Dose-finding Study of Silodosin in Patients With Urinary Calculi
The purpose of this study is to evaluate the efficacy and the safety of silodosin in urinary calculi patients.
- Trial name
- NCT01539265
- Testing
- silodosin
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Chronic Kidney Diseases
Late Feasibility Study to Evaluate Safety and Efficacy of AWAK PD Device in Subjects With ESKD.
The goal of this late feasibility clinical trial is to evaluate the safety and effectiveness of the Automated Wearable Artificial Kidney (AWAK) peritoneal dialysis (PD) device in subjects with end-stage kidney disease.
- Trial name
- NCT05827588
- Testing
- AWAK PD
- Where
- Singapore
- Volunteers
- 12 people
- Sponsor
- AWAK Technologies Pte Ltd
IV Catheter-Related Infection or Complication
A Clinical Trial Using a New Medical Device to Evaluate Its Impact on IV Care and Clinical Complications
A clinical trial comparing two groups of patients that are randomized into one group having SafeBreak Vascular attached to their peripheral IV lines and a second control group that receives the current standard of care (no…
- Trial name
- DIPPER (NCT04469218)
- Testing
- SafeBreak Vascular
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Lineus Medical
Non-valvular Atrial Fibrillation
A Nationwide Observational Study Looking at Effectiveness and Bleeding Complications of NOACs vs. VKA in Non-valvular Atrial Fibrillation Patients.
Using mandatory nationwide registries and possibly hospital electronic medical records in Norway, the researchers want to understand how well a group of drugs called "non-vitamin K antagonist oral anticoagulants" (rivaroxaban …
- Trial name
- PROTECT-AF (NCT03715725)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Apixaban (Eliquis), Dabigatran etexilate (Pradaxa)
- Where
- Norway
- Volunteers
- 70,000 people
- Sponsor
- Bayer
Chronic Kidney Diseases, Renal Disease
Evaluation of Renastep
Evaluation of Renastep is a 28-day long, prospective nutritional study that will recruit 15 patients aged between 3 and 18 years of age with Chronic Kidney Disease.
- Trial name
- Renastep (NCT03602937)
- Testing
- Renastep
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Vitaflo International, Ltd
Vaginitis, Bacterial Vaginosis
Real-world Performance and Safety of Cerviron® in the Treatment of Vaginitis
Vaginitis is a broad term that includes a range of gynecological disorders characterized by infection of vaginal mucosa, inflammation of vulva and alteration of the normal vaginal microflora.
- Trial name
- NCT05652959
- Testing
- Cerviron®
- Where
- 10 sites in Romania
- Volunteers
- 111 people
- Sponsor
- Perfect Care Distribution
Urinary Incontinence, Pelvic Floor Disorders
Performance and Safety of the PHENIX LIBERTY, a Medical Device for Electrostimulation and Biofeedback, in the Treatment of Pelvic Static Disorders in Women With Urinary Incontinence.
The goal of this clinical trial is to evaluate the short-term improvement in urinary incontinence after perineo-sphincter rehabilitation using functional electrostimulation and biofeedback (PHENIX LIBERTY VIVALTIS device) in…
- Trial name
- IncontiLib (NCT05938855)
- Testing
- Electrical stimulation and biofeedback with the medical device Phenix Liberty
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Vivaltis
Hyperuricosuria, Kidney Stones
Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones
The purpose of this study is to determine the efficacy of febuxostat, once daily (QD), compared to allopurinol or placebo in patients with excessive amounts of uric acid in their urine and who have recently had kidney stones.
- Trial name
- NCT01077284
- Testing
- Febuxostat, Allopurinol
- Where
- 28 sites in United States
- Volunteers
- 99 people
- Sponsor
- Takeda
Pre-surgical Anxiety, Blood Glucose Concentration
Vis Pre Surgery Medical Food Validation Study
A pre-market, confirmatory, prospective, interventional, clinical investigation to confirm the clinical safety and performance profile of Vis Pre-surgeryTM that the medical food will reduce pre and post-surgical complications…
- Conditions
- Pre-surgical Anxiety, Blood Glucose Concentration, Blood Cortisol Levels, Electrolyte Levels
- Trial name
- NCT07359222
- Testing
- Pre-surgical medical food
- Where
- India
- Volunteers
- 67 people
- Sponsor
- TM Nutrition LLC
Bacterial Vaginosis
Performance and Safety of Lactal Gel for Treatment of Bacterial Vaginosis
The aim of this study is to find out how well the medical device Lactal Gel works and how safe it is. The product will be used to treat bacterial vaginosis in a group of fifty women aged 18 years or older.
- Trial name
- NCT07241871
- Testing
- Lactal Gel (Class IIa medical device)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Rolf Kullgren AB
Bacterial Vaginosis, Candidal Vaginitis
Efficacy and Safety of a Vaginal Ovule Medical Device for Bacterial Vaginosis and Candidal Vaginitis (ROVUL25).
This is a randomized, double-blind, placebo-controlled, two-arm parallel-group clinical study evaluating the efficacy and safety of INTIMIQUE OVULI, a Class IIa vaginal medical device, in adult women (18-60 years) diagnosed with…
- Trial name
- ROVUL-25 (NCT07703241)
- Testing
- Class IIa vaginal medical device supplied as vaginal ovules, intended as an adjuvant in prevention of vaginal infections and symptoms.
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- ROELMI HPC
Chronic Kidney Disease, Type 2 Diabetes Mellitus
An Observational Study to Learn More About How Safe Finerenone is and How Well it Works in Indian People With Chronic Kidney Disease and Type 2 Diabetes in Routine Medical Practice
Availability of this study's data will later be determined according to Bayer's commitment to the EFPIA/PhRMA "Principles for responsible clinical trial data sharing". This pertains to scope, timepoint and process of data access.
- Trial name
- IN-REALITY (NCT06763146)
- Testing
- Finerenone (Kerendia, BAY948862)
- Where
- India
- Volunteers
- 1,200 people
- Sponsor
- Bayer
Renal Artery Stenosis
Comparison of Best Medical Treatment Versus Best Medical Treatment Plus Renal Artery Stenting
The clinical investigation is a prospective, international, multi-centre, randomized (1:1) trial with follow ups at 2, 6, 12 months and 3 years.
- Trial name
- RADAR (NCT00640406)
- Testing
- Dynamic Renal Stent plus Best Medical Treatment, Best Medical Treatment
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- Biotronik AG
Embolism
Efficacy and Safety of Low-molecular Weight Heparin for Thromboprophylaxis in Acutely Ill Medical Patients
Acutely ill immobilized patients are at a high risk for thromboembolic events including deep venous thrombosis or pulmonary embolism.
- Trial name
- NCT00311753
- Testing
- Certoparin, Heparin
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 342 people
- Sponsor
- Novartis Pharmaceuticals
Bacterial Vaginosis (BV), Recurrent Bacterial Vaginosis
Evaluation of the Medical Device Vagitab - T as Adjuvant Therapy in Patients With Bacterial Vaginosis.
This clinical trial is looking at how well and safely the vaginal administration of Vagitab-T works . Vagitab-T is already on the market in several countries in Europe as a medical device.
- Trial name
- Vagitab (NCT06725888)
- Testing
- Vagitab -T vaginal tablets. Components: tyndallized probiotic L. plantarum HA-119, lactic acid, and xylo-oligosaccharides, lauryl glucoside, and macrogol 3350:
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- S.I.I.T. Srl
Heart Failure, Acute Decompensated Heart Failure
Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance
Evaluation of the safety and efficacy of the ModulHeart System in patients hospitalized with acute decompensated heart failure (ADHF) and diuretic resistance
- Conditions
- Heart Failure, Acute Decompensated Heart Failure, Cardiorenal Syndrome, Heart Failure, Congestive
- Trial name
- NCT06174623
- Testing
- ModulHeart Support
- Where
- 5 sites in Australia, Georgia
- Volunteers
- 5 people
- Sponsor
- Puzzle Medical Devices Inc.
Acute Kidney Injury
A Sample Collection Study to Validate the Astute Medical NephroCheck Test in Critically Ill Subjects at Risk for Acute Kidney Injury
The objective of this sample collection study is to collect blood and urine samples. This study is observational and will have no impact on the medical management of the subject.
- Trial name
- NCT01573962
- Where
- 23 sites in United States
- Volunteers
- 420 people
- Sponsor
- Astute Medical, Inc.
Breast Implant Revision, Breast Augmentation Complications
Scaffold-guided Breast Implant Revision and Primary Breast Augmentation Surgery
The objective of the clinical investigation is to demonstrate safety and clinical performance of the absorbable polycaprolactone (PCL) breast scaffold combined with autologous fat grafting (AFG) for primary breast augmentation…
- Conditions
- Breast Implant Revision, Breast Augmentation Complications, Primary Breast Augmentation Surgery
- Trial name
- NCT07367698
- Testing
- Implantation of the PCL Breast scaffold with autologous fat grafting
- Where
- 3 sites in Australia
- Volunteers
- 87 people
- Sponsor
- BellaSeno Pty Ltd