Clinical trials: Medical Devices
Minimally Invasive Surgical Procedures
Homemade Versus Commercialized Single-access Port Devices in Single-incision Laparoscopic Appendectomy
Homemade and commercialized single-assess port devices are two kinds of port devices commonly used for single-incision laparoscopic appendectomy.
- Trial name
- NCT05528003
- Testing
- Commercialized single-access port devices
- Volunteers
- 161 people
- Sponsor
- National Taiwan University Hospital
Cataract
Intra and Postoperative Outcomes With 3 Injectors
This randomized clinical trial compares subjective performance during Intraocular lens (IOL) implantation, as well as incision enlargement and anterior segment morphology on OCT when IOL implantation was performed during…
- Trial name
- NCT02466256
- Testing
- Intraocular lens implantation, Autosert Injector, Royale Injector
- Volunteers
- 120 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Contraception
Maintaining Intrauterine Devices (IUDs) in Teens (MINT): A Randomization Trial
This is a pilot study to determine the feasibility for a randomized controlled trial of two forms of intrauterine contraception: the Levonorgestrel intrauterine system (LNG-IUS) and the Copper T 380A.
- Trial name
- MINT (NCT00653159)
- Testing
- Levonorgestrel-releasing intrauterine device (LNG-IUS), Copper T380A intrauterine device (CuT380A)
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Heart Failure, Heart-Assist Devices
Partial Left Ventricular Support in Advanced Heart Failure
Heart failure is a common condition, and the number of people with advanced disease continues to increase. We need new treatments that improve patients' symptoms and extend life.
- Trial name
- NCT01879670
- Testing
- CircuLite Synergy left ventricular assist device
- Where
- 2 sites in Belgium, United Kingdom
- Volunteers
- 2 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Bradycardia, Arrhythmia
The Impact of Video-based Cardiac Rehabilitation Education in Patients With CIEDs
Cardiac rehabilitation has the beneficial effects of secondary prevention and social psychological and physical health status in patients with cardiovascular diseases.
- Conditions
- Bradycardia, Arrhythmia, Heart Failure
- Trial name
- CIEDs (NCT06503445)
- Testing
- education video
- Where
- Taiwan
- Volunteers
- 85 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
NSCLC
Clinical Trial to Evaluate the Efficacy and Safety of Pulsed Electric Field Ablation Devices in the Treatment of Lung Tumors
The goal of this clinical trial is to verify the efficacy and safety of pulsed electric field (PEF) treatment of early-stage unreseectable non-small cell lung cancer(NSCLC) patients.
- Trial name
- NCT06739031
- Testing
- PEF Treatment
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Energenx Medical LTD.
Diabetes
The Characterization of Blood Volumes of Commercially Available Lancing Devices
Characterize expressed blood volume ≥1μL across representative, commercially available lancing device systems using finger sticks.
- Trial name
- NCT01914302
- Testing
- Delica Lancing Device, Flash Lancing Device, Easy Touch Lancing Device
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Facet Technologies
Wrinkle
Clinical Study for the Evaluation of the Safety and Effectiveness of Use of a Poly-L Lactic Acid Injectable Filler for the Aesthetic Treatment of Nasolabial Folds
The purpose of this study is to assess the effectiveness and safety of Gana V, a Poly L-lactic acid filler for the aesthetic treatment of nasolabial folds, in comparison with Sculptra.
- Trial name
- PLLA (NCT05215054)
- Testing
- Gana V®, Sculptra®
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- GCS Co., Ltd
Uterine Hemorrhage
Management of Initial Bleeding/Spotting Associated With the Levonorgestrel-releasing Intrauterine System (MIRENA)
The purpose of the study is to investigate if the study drugs (tranexamic acid or mefenamic acid) can control irregular bleeding during the first 3 months of using Mirena.
- Trial name
- NCT01295294
- Testing
- Tranexamic acid, Mefenamic acid, Mirena (Levonorgestrel IUS, BAY86-5028)
- Where
- 12 sites in Denmark, Ireland and 1 more
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Bayer
Low Back Pain
Evaluation of the Japet.W+ Medical Device for Low Back Pain Management
The JAPET.W+ medical device is a new dynamic distraction support system. It could be considered as a new solution in the therapeutic arsenal for managing common low back pain.
- Trial name
- EXODOMICILE (NCT07195422)
- Testing
- Japet.W+, Control (Standard treatment)
- Where
- 2 sites in France
- Volunteers
- 102 people
- Sponsor
- Japet Medical Devices
Chronic Obstructive Pulmonary Disease (COPD)
Comparison of Two Positive Expiratory Pressure Devices in Stable COPD Patients
Positive expiratory pressure (PEP) therapy is a device aiding airway clearance and secretion mobilization, also prevent the small airway from collapsing.
- Trial name
- NCT02817529
- Testing
- Pulmonica, RC-Cornet
- Sponsor
- Rush University Medical Center
Gram Negative Meningitis, Post Traumatic Bacterial Meningitis
Amikacin Penetration Into the Cerebrospinal Fluid
The limited available data precludes establishing an antibiotic regimen in patients suffering from bacterial meningitis after head trauma, or spontaneous bleeding Understanding the disposition of Amikacin administered…
- Trial name
- NCT00362245
- Testing
- Systemic and Intra-Thecal Amikacin Therapy
- Where
- Israel
- Sponsor
- Rambam Health Care Campus
Cardiac Devices Infection
Reduction of Antibiotherapy Duration for Infections on Implantable Extra Cardiac Devices Leads
The design is an Open-label randomized controlled multicenter non-inferiority trial with blinded assessor which compares 2 antibiotic strategy: 14-day antibiotic therapy after removal of infected material (experimental group)…
- Trial name
- RAID (NCT06203769)
- Testing
- 14-day antibiotic therapy, 28-day antibiotic therapy
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Skeletal Class II Malocclusion, Dental Overjet
Removable Devices in Overjet Reduction
The goal of this clinical trial si to compare two removable devices used to treat the mandibular retrusion in growing patients. The main questions it aims to answer are: the efficacy of the two devices in the reduction of the…
- Trial name
- RemoDevOJ (NCT06955637)
- Testing
- dental movement
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Ischemic Stroke
Assessing the Safety and Effectiveness of a Neurological Thrombectomy Medical Device for Acute Ischemic Stroke
The Jacobs Institute is participating in a Sponsor Investigator study designed to collect prospective clinical evidence to evaluate the use of a neurological thrombectomy device for clot retrieval in acute ischemic patients
- Trial name
- NCT05074186
- Testing
- neurological thrombectomy device is an investigational device.
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Jacobs institute
Mid-face Volume Deficit
Efficacy and Safety of Rejuviel V in the Correction of Midface Volume Deficit
The purpose is to evaluate the efficacy and confirm the safety of Rejeunesse Contour® with Lidocaine compared to Juvederm® Voluma® with Lidocaine for the temporary improvement of mid-face volume (including the cheekbone area, the…
- Trial name
- NCT07162610
- Testing
- Rejuviel V® with lidocaine, JUVEDERM® VOLUMA® with lidocaine
- Where
- South Korea
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- PharmaResearch Co.,Ltd
Hallux Valgus
Correction of Hallux Valgus with the Nexis® PECA Bunion Implantable Osteosynthesis Medical Device
The Nexis® screw system is a range of osteosynthesis screws for the foot. Nexis® Bunion Screws are Class IIb implantable medical devices.
- Trial name
- PECA (NCT05361317)
- Testing
- Nexis® PECA Bunion device
- Where
- 4 sites in France
- Volunteers
- 86 people
- Sponsor
- Novastep
Spinal Disorders/Injuries
A Multi-Center Post-Market Data Collection Protocol to Evaluate the Performance of Orthofix Spine Devices
This protocol is designed to study Orthofix regulatory approved and commercially available spine devices to generate Real World Evidence (RWE) of device safety and performance in the treatment of patients with spine injuries…
- Trial name
- RWE Spine (NCT05082090)
- Testing
- Spinal Surgery
- Where
- 20 sites in United States, Germany and 2 more
- Volunteers
- 2,000 people
- Sponsor
- Orthofix Inc.
Down Syndrome, Gross Motor Delay
Up, Down, and All Around: Evaluating Mobility Devices for Young Children With Developmental Disabilities and Delays
This research study will examine young children with Down syndrome's initial experiences with mobility devices. Children's biomechanics and exploration will be quantified while they are using both an overground partial bodyweight…
- Conditions
- Down Syndrome, Gross Motor Delay, Cerebral Palsy
- Trial name
- NCT06591559
- Testing
- Permobil Explorer Mini, Portable Mobility Aid for Children (PUMA)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Partial Meniscectomy
The Influence of Wedge Insoles After Partial Meniscectomy
Research on the implications of orthotic devices and the recovery after knee arthroscopy are widely known. But only a handful of specific issues have been studied to date.
- Trial name
- NCT02190188
- Testing
- Wedge Insole 5mm, Knee Brace
- Where
- Austria
- Volunteers
- 63 people
- Sponsor
- Medical University Innsbruck