Clinical trials: Medical Disorders
Neuromuscular Blockade, Human Characteristics
Sparing in Neuromuscular Blockade in COVID 19 ICU
This is a retrospective case-controlled study of the effect of the use of a neuromuscular blockade (NMB) monitor on the consumption of NMB agents in patients under mechanical ventilation in the context of COVID-19.
- Conditions
- Neuromuscular Blockade, Human Characteristics, Complication of Medical Care, Intensive Care Unit Acquired Weakness
- Trial name
- TOF-COVID (NCT04459533)
- Testing
- TOF protocol
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Hospices Civils de Lyon
Anxiety
Effect of a Social Script iPAD Application for Children With Autism Spectrum Disorder
The purpose of the research is to test the effectiveness of the social story intervention delivered using the iPAD application "Going to Imaging" on the anxiety, challenging child behaviors, child injuries and completion rates…
- Trial name
- NCT01655485
- Testing
- Patient teaching
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Pancreatic Cancer
Combination of SBRT With Sequential S-1 for Treating Locally Advanced Pancreatic Cancer
The safety and efficacy of combination of SBRT with sequential S-1 in treating patients with locally advanced pancreatic cancer and poor medical conditions will be evaluated.
- Trial name
- NCT02704143
- Testing
- combination of Cyberknife with S-1
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Changhai Hospital
Intracranial Aneurysm
Clinical Performance Evaluation of RDX-Aneurysm for Detecting Intracranial Aneurysms on TOF-MRA
This retrospective, multi-center, observational case-control study evaluates the standalone performance of RDX-Aneurysm, a computer-assisted detection software, for detecting and marking suspected saccular intracranial aneurysm…
- Trial name
- RDX-Aneurysm (NCT07655635)
- Where
- 3 sites in Taiwan
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Autism Spectrum Disorder, Anxiety
Investigating a Marijuana-based Compound as a Treatment for Anxiety in Autistic Adults
The goal of this clinical trial is to learn if drug ABC works to treat severe asthma in adults. It will also learn about the safety of drug ABC.
- Trial name
- NCT06526208
- Testing
- MB-IMP
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Southwest Autism Research & Resource Center
Rheumatoid Arthritis, Non-inflammatory Degenerative Joint Disease
PMCF Study on the Safety, Performance and Clinical Benefits Data of the NexGen TM Augmentation Patella
The study is a single-center, retrospective and prospective, non-randomized, non-controlled and consecutive series post-market study.
- Conditions
- Rheumatoid Arthritis, Non-inflammatory Degenerative Joint Disease, Functional Deformity, Revision Total Knee Arthroplasty
- Trial name
- NCT05253976
- Where
- Switzerland
- Sponsor
- Zimmer Biomet
Fatigue, Sleep Deprivation
Effect and Utilization of Protected Time Among Interns on Extended Duty-Hour Call Shifts
This study will test the feasibility and effectiveness of protected time for physicians in training during 30 hour shifts in a medical intensive care unit. The primary outcome will be fatigue.
- Conditions
- Fatigue, Sleep Deprivation, Depression
- Trial name
- NCT00983008
- Testing
- Protected time and Dedicated time
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Providence Health & Services
Type 1 Diabetes Mellitus
Assessment of Quality of Life and Satisfaction With Medical Care of Pediatric Type 1 Diabetes Mellitus Patients
The purpose of this study is to evaluate the change score for the PedsQL short form Diabetes and Core Modules and the Patient Assessment of Chronic Illness Care measured at baseline (before changing care delivery models) and 12…
- Trial name
- NCT00450489
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Intensive Care
Efficacy and Safety of Three Insulin Protocols in Medical Intensive Care Unit Patients
To evaluate the efficacy and safety of three insulin algorithms in medical ICU patients (MICU).
- Trial name
- NCT00410852
- Testing
- Computer-assisted IV insulin infusion protocol (algorithm A), Leuven Strict glycemic control protocol (Algorithm B), Conventional Intermittent Insulin Protocol (Algorithm C)
- Where
- 5 sites in Brazil
- Volunteers
- 168 people
- Sponsor
- Hospital Israelita Albert Einstein
Heart Failure
Resynchronization for Ambulatory Heart Failure Trial in Patients With Preserved LV Function
This trial will compare two management strategies for HF patients with preserved LV function in sinus rhythm and LBBB. The control group will be treated with practice guideline optimal medical therapy for HF.
- Trial name
- NCT04582578
- Testing
- CRT
- Where
- Canada
- Sponsor
- Anthony Tang
Upper Extremity Impairments, Cerebral Palsy (CP)
Obi Medical Robot: Evaluating Effectiveness Related to Usability
This mixed-methods usability study evaluates the effectiveness of the Obi Gen 3 robotic feeding device in meeting user needs among providers, caregivers, and patients.
- Conditions
- Upper Extremity Impairments, Cerebral Palsy (CP), ALS - Amyotrophic Lateral Sclerosis, Rett Syndrome
- Trial name
- NCT07151950
- Testing
- One-week trial of Obi Medical device, which provides robotic assistance with feeding to persons with upper extremity impairments who are unable to self-feed in the traditional manner using utensils
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Desin LLC
Venous Thromboembolism
A Study in Europe Based on Medical Records That Looks at the Safety of Dabigatran in Children Below 2 Years of Age Who Have Had a Blood Clot and Are at Risk of Developing Another Blood Clot
The study is designed to collect and evaluate Dabigatran Etexilate (DE) safety in the context of routine anticoagulation care provided in the European Union (EU)/European Economic Area (EEA) for children under 2 years of age.
- Trial name
- DaPaR (NCT05536791)
- Testing
- Dabigatran Etexilate (DE)
- Where
- 6 sites in Germany, Netherlands and 2 more
- Sponsor
- Boehringer Ingelheim
Acute Kidney Injury, Surgery-Complications
Development of Synthetic Medical Data Generation Technology to Predict Postoperative Complications
<Development of synthetic medical data generation technology to predict postoperative complications> In order to develop a model for predicting the occurrence of complications after surgery, it is necessary to establish a cohort…
- Conditions
- Acute Kidney Injury, Surgery-Complications, Nephropathy
- Trial name
- NCT05986474
- Where
- South Korea
- Volunteers
- 410,000 people
- Sponsor
- Seoul National University Hospital
COVID-19, Children With Medical Complexity (CMC)
ReSET Aim 1a: Restarting Safe Education and Testing for Children With Medical Complexity - Feasibility of In-home Cohort COVID-19 Testing Strategies, and Associations With CMC Parent Perceptions About In-person School Attendance
The purpose of this research study is to learn about the factors parents consider when deciding whether their child will go to school in-person or attend from home.
- Trial name
- NCT04895085
- Testing
- BinaxNOW Rapid Antigen System
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Emergencies, Epidemic Disease
Impact of the Qatar 2022 FIFA World Cup on PED Use and Misuse Patterns
A retrospective cohort study to explore the impact of the FIFA World Cup 2022 Qatar on paediatric emergency department attendance at two tertiary centres during unprecedent winter viral epidemics.
- Conditions
- Emergencies, Epidemic Disease, Pediatric ALL, Electronic Medical Record
- Trial name
- NCT05818215
- Testing
- NO intervention
- Where
- Switzerland
- Volunteers
- 18,000 people
- Sponsor
- Pediatric Clinical Research Platform
Recognition of Thrombectomy Candidate
Implementation of Finnish Prehospital Stroke Scale to Emergency Medical Services
The investigators have developed a simple prehospital stroke scale (FPSS), containing 5 dichotomized items to recognize both large and small artery thrombi of the brain.
- Trial name
- NCT03520335
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Bone Disease, Metabolic, Diabetes Mellitus, Type 2
Glucose-dependent INsulinotropic Polypeptide: Effect on Bone Remodelling and Cell Activity (GINEBRA)
Glucose-dependent insulinotropic polypeptide (GIP) is released by the intestines in response to food intake and increases insulin secretion.
- Conditions
- Bone Disease, Metabolic, Diabetes Mellitus, Type 2, Obesity and Obesity-related Medical Conditions
- Trial name
- GINEBRA (NCT06790225)
- Testing
- Glucose-dependent Insulinotropic Polypeptide (GIP)
- Where
- Denmark
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Pectus Excavatum
Multicenter Trial of Magnetic Mini-Mover for Pectus Excavatum
This study is a Phase 3, multicenter, non-randomized study to evaluate the safety and efficacy of the next-generation outpatient Magnetic Mini-Mover Procedure (3MP) in 15 patients aged 8-14 years for the correction of pectus…
- Trial name
- 3MP (NCT01327274)
- Testing
- Magnetic Mini-Mover Procedure (Magnimplant)
- Where
- 3 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michael Harrison
DFS
A Multicenter Randomized Controlled Study of Interventional Treatment for Operable Stage Ⅱ-Ⅲ Non-small Cell Lung Cancer With Potential Recurrence as Minimal Residual Disease(MRD) Positive
A prospective, multicenter clinical study designed to explore the efficacy of adaptive therapy based on MRD status in patients with stage II-III non-small cell lung cancer(NSCLC) after treatment.
- Trial name
- NCT06524518
- Testing
- Chemotherapy combined with immunization
- Where
- China
- Volunteers
- 213 people
- Sponsor
- Xuanwu Hospital, Beijing
Diabetes Mellitus Type 2
Shared Medical Visits for Spanish-speaking Patients With Type 2 Diabetes
The investigators seek to apply a shared medical visit model and interdisciplinary approach to Spanish-speaking patients. The investigators will evaluate the patient's hemoglobin A1c as a marker of glycemic control and evaluate…
- Trial name
- SMV (NCT02836015)
- Testing
- Shared Medical Visit
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nebraska