Clinical trials: Medication Adherence, open to volunteers
Medication Adherence
Investigation of a Patient Support Intervention for Statin Medication Adherence
Statins have been demonstrated to significantly reduce the risk of cardiovascular disease, but adherence to these medications is suboptimal.
- Trial name
- NCT06972979
- Testing
- Text Message Gamification and Remote Support
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Ascension Health
HIV Infections
Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Atlanta
This study applies Social Cognitive Theory to develop behavioral interventions promoting PrEP adherence. It seeks to adapt and test the enhanced HMP app for feasibility and acceptability among Black adolescents and young adults…
- Trial name
- NCT07535346
- Testing
- Health MPowerment App
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV
Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Alabama
This study applies Social Cognitive Theory to develop behavioral interventions promoting PrEP adherence. It seeks to adapt and test the enhanced HMP app for feasibility and acceptability among Black adolescents and young adults…
- Trial name
- NCT06876324
- Testing
- HealthMPowerment App
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emory University
Smoking Cessation
Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation
No published studies to date have evaluated the combined impact of varenicline and oral nicotine replacement therapy (NRT) on smoking cessation in a randomized trial.
- Trial name
- COMBOII (NCT07099638)
- Testing
- Varenicline (VAR), Nicotine lozenge (NRT), Smartphone intervention with adherence components (COMBO-A)
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Depression, Posttraumatic Stress Disorder
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa
Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV.
- Conditions
- Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
- Trial name
- NCT05624931
- Testing
- Brief CBT-Based Intervention, Enhanced Treatment as Usual
- Where
- 2 sites in United States, South Africa
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Hypertension, Medication Adherence
Effectiveness and Adoption of the TelTex4BP Intervention Among Adults With Hypertension in Nepal
Despite evidence of preventing cardiovascular disease (CVD) risk through lifestyle changes, many patients with hypertension (HTN) do not comply with this and suffer from CVD and other complications.
- Conditions
- Hypertension, Medication Adherence, Blood Pressure, Cardiovascular Diseases
- Trial name
- TelTex4BP (NCT05979168)
- Testing
- Phone call and text Messages
- Where
- 2 sites in Nepal
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Central Department of Public Health
HIV Infections, Mental Health
Testing the WeCare Intervention to Address Mental Health and Medication Adherence Challenges Among MSM in South Africa
The goal of this clinical trial is to learn if the WeCare intervention-an adapted Friendship Bench program that integrates problem-solving therapy, minority-stress-informed content, and explicit PrEP/ART adherence skills-improves…
- Trial name
- NCT07226323
- Testing
- WeCare, Standard of Care
- Where
- South Africa
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Emory University
Medication Adherence, Heart Failure
Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies
People with heart failure who do not take their medications as prescribed are at high risk of complications leading to hospitalization, death and poor quality of life.
- Trial name
- FamLit_HF (NCT05548413)
- Testing
- FamLit, Attention Control
- Where
- United States
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Jia-Rong Wu
Medication-related Problems, Self-reported Medication Adherence
Improving Medication Therapy Through a Digital Interdisciplinary Medicine Therapy Optimisation Model
In this study, a telepharmacy service in primary care for home-living older adults in Northern Sweden's rural areas will be developed and evaluated.
- Conditions
- Medication-related Problems, Self-reported Medication Adherence, Health-related Quality of Life, Beliefs About Medicines
- Trial name
- MTO (NCT05629936)
- Testing
- Telepharmacy service
- Where
- 2 sites in Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Umeå University
Dry Eye Disease (DED), Glaucoma
Blinking Exercise Study
The goal of this clinical trial is to evaluate whether a structured blinking exercise can improve symptoms and signs of dry eye disease (DED) in adults with glaucoma who are using topical intraocular pressure-lowering…
- Trial name
- NCT07554937
- Testing
- Structured Blinking Exercise Training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
HIV Infections, Substance Use
Women Focused Encounters for Resilience Independence Strength and Eudaimonia
The goal of this combination Type 1 hybrid and observational study is to evaluate the impact of a peer delivered intervention of acceptance and commitment therapy (ACT) + exercise + social support to address the substance…
- Conditions
- HIV Infections, Substance Use, Trauma, Medication Adherence
- Trial name
- WE RISE (NCT06216600)
- Testing
- Acceptance and Commitment Therapy (ACT), Body weight circuit training, Empathetic social support
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
HIV Prevention, Contraceptive Usage
Peer-led Service Delivery Model for Pregnant and Lactating Adolescent Girls and Young Women in Zimbabwe
This is a pilot cluster-randomized control trial co-led by Dr. Valentina Cambiano, Associate Professor of Epidemiology at University College London, UK and Professor Euphemia Sibanda, Research Director at the Centre for Sexual…
- Conditions
- HIV Prevention, Contraceptive Usage, Adherence, Medication
- Trial name
- Ontanga (NCT07546344)
- Testing
- Peers who are stars
- Where
- 3 sites in Zimbabwe
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University College, London
Preventative Medicine
Using a Telehealth and Shared Decision-Making Model to Address Preventative Medicine Strategies Among Communities in Louisiana
This study is a 12-18 month behavioral intervention study to assess the impact of enrolling individuals a clinical pharmacist run Telehealth education focused on wellness and preventive health strategies.
- Trial name
- NCT05676970
- Testing
- Telehealth: Personalized Preventative Medicine Strategies, TeleHealth: Preventative Medicine Education
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Medication Adherence, HIV/AIDS
A Mobile Gaming App to Improve Adherence to PrEP
In this study, the investigators will test the mobile game, Viral Combat, for efficacy and acceptability among diverse participants, ages 15-34 years, receiving PrEP care in clinical settings in New England and Mississippi.
- Trial name
- NCT05762705
- Testing
- Multilevel Gaming Adherence Intervention, Treatment as Usual +
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Anticoagulants; Circulating, Hemorrhagic Disorder
MEdication Counselling Models for Outpatient oRal antIcoaguLation
The goal of this clinical trial is to investigate whether telepharmacy-led counselling can improve medication adherence, knowledge, and hospitalisation/mortality compared with pharmacist-led counselling in adult outpatients…
- Trial name
- MEMORIAL (NCT06290440)
- Testing
- Telepharmacy-led counselling, Pharmacist-led counselling
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Gia Dinh People Hospital
HIV Infections, Sexually Transmitted Diseases
Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention
The purpose of this study is to compare the effectiveness of two mobile health technologies (text messaging or a mobile app) designed to help people take HIV pre-exposure prophylaxis (PrEP) as directed by the clinic.
- Trial name
- PCORI PrEP (NCT04855773)
- Testing
- PrEPmate, Dot Diary
- Where
- 4 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.