Clinical trials: Medication Adherence, open to volunteers
Anxiety, Prostate Cancer
proState Cancer Health Education to pRomote Early sreENing Uptake (SCREEN): A Pilot Randomised Control Trial
Prostate cancer is an issue of significant public health concern. Yet in low- and middle-income countries like Nigeria, men are adversely affected due to factors including poor early prostate cancer screening uptake.
- Conditions
- Anxiety, Prostate Cancer, Health Education, Screening and Brief Interventions
- Trial name
- SCREEN (NCT07800390)
- Testing
- proState Cancer awareness education to pRomote Early screENing uptake, Control group
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Teesside University
Chronic Disease, Memory Impairment
Impact of a Mobile Application-Based Medication Reminder on Treatment Adherence Among Patients With Chronic Diseases and Memory Impairment: A Nursing Leadership Perspective
This study aims to evaluate the impact of using a mobile application-based medication reminder on medication adherence among patients diagnosed with chronic diseases and memory impairment.
- Trial name
- NCT07718334
- Testing
- Mobile Application-Based Medication Reminder
- Where
- 2 sites in Egypt
- Volunteers
- 193 people
- Sponsor
- Mansoura University
Cancer
Optimization of the Targeted Anticancer Therapies
The study includes an observational pharmacokinetic study and an interventional medication adherence study. The purpose of this study is 1) to describe the concentration-time profiles of targeted anticancer drugs and to…
- Trial name
- OpTAT (NCT04484064)
- Testing
- Adherence program
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Patient Satisfaction, Drug Adherence
Tenofovir Alafenamide Switch Therapy in Chronic Hepatitis B
Chronic hepatitis B (CHB) patients may be unsatisfied to entecavir (ETV) therapy due to the inconvenience in drug taking, i.e., fasting for more than 2 hours and/or dose adjustment according to estimated glomerular filtration…
- Conditions
- Patient Satisfaction, Drug Adherence, Efficacy, Self, Safety Issues
- Trial name
- NCT05583006
- Testing
- tenofovir alafenamide (TAF)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taichung Veterans General Hospital
HIV, Hypertension
INTEGRATE-RX: Integrating Clinical Pharmacists in HIV Care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden
The risk of heart attacks and stroke is two times higher among people living with HIV (PLWH), as compared to the general population.
- Conditions
- HIV, Hypertension, Cardiovascular Disease Prevention
- Trial name
- INTEGRATE-RX (NCT07711366)
- Testing
- INTEGRATE-RX
- Where
- 2 sites in Kenya
- Volunteers
- 450 people
- Sponsor
- Temple University
Endometriosis, Chronic Pain
Therapeutic-educational Physiotherapy on Pain, Physical-functionality and Quality of Life in Women With Endometriosis.
This is a randomized clinical trial that will be carried out in women with endometriosis divided into two groups: the experimental group (EG) that will receive therapeutic-educational physiotherapy, which will combine therapeutic…
- Conditions
- Endometriosis, Chronic Pain, Women's Health
- Trial name
- PHYSIO_ENDOM (NCT06212349)
- Testing
- therapeutic-educational physiotherapy and pain education program, pain education program
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- University of Valencia
Medication Adherence
Smart About Meds (SAM) RCT
Introduction: Almost half of patients discharged from hospital are re-admitted or return to the emergency department (ED) within 90 days.
- Trial name
- NCT05371548
- Testing
- SAM mobile application
- Where
- Canada
- Volunteers
- 3,250 people
- Sponsor
- Robyn Tamblyn
Hypertension, High Blood Pressure
Blood Pressure Care for Advancing Real-World Evidence (BPCARE)
The goal of this randomized clinical trial is to determine whether a community health worker-delivered, multi-component behavioral intervention can improve antihypertensive medication adherence and blood pressure control among…
- Trial name
- BPCARE (NCT07398391)
- Testing
- BPCARE Intervention
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of California, San Diego
Opioid-use Disorder, Medication Adherence
The Youth Opioid Recovery Support (YORS) Intervention
Youth are disproportionately affected by the current opioid crisis with catastrophic consequences, and young adults with opioid use disorder (OUD) often struggle with adherence to relapse prevention medications.
- Trial name
- YORS (NCT04173416)
- Testing
- Youth Opioid Recovery Support (YORS)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Potomac Health Foundations
Cardio-vascular Disease, Depression Disorders
Supporting Patients Starting New Medicines: Evaluating the myCare Start Service in Switzerland
In Phase B, the aim is to evaluate the myCare Start service in routine care within the ambulatory primary care medicine and community pharmacy setting in Switzerland.
- Conditions
- Cardio-vascular Disease, Depression Disorders, Diabetes, COPD
- Trial name
- myCare Start-I (NCT07036471)
- Testing
- myCare Start
- Where
- Switzerland
- Volunteers
- 1,600 people
- Sponsor
- University of Geneva, Switzerland
Smoking Cessation
Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation
No published studies to date have evaluated the combined impact of varenicline and oral nicotine replacement therapy (NRT) on smoking cessation in a randomized trial.
- Trial name
- COMBOII (NCT07099638)
- Testing
- Varenicline (VAR), Nicotine lozenge (NRT), Smartphone intervention with adherence components (COMBO-A)
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Medication Adherence, Quality of Life
ECHO-COPD: Impact of a Pharmacist-Led Health Belief Model-Based Educational Intervention Among Chronic Obstructive Pulmonary Disease Patients
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease associated with substantial morbidity and mortality, impaired quality of life, and healthcare costs.
- Conditions
- Medication Adherence, Quality of Life, Cost, Health Belief Model
- Trial name
- ECHO-COPD (NCT07815353)
- Testing
- Pharmacist-Led HBM-Based Educational Intervention
- Where
- Saudi Arabia
- Volunteers
- 140 people
- Sponsor
- Rabia Hussain
Acute Lymphoblastic Leukemia, Pediatric
Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication Adherence: Study 3
The current study will assess the acceptability and feasibility of the CareMeds intervention with a larger sample (N = 100) across multiple sites in Buffalo, NY, and Atlanta, GA.
- Trial name
- NCT06074666
- Testing
- CareMeds Intervention, Usual Care Group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Roswell Park Cancer Institute
Diabetic Foot Ulcer (DFU), Diabetes Mellitus
DiaFootCare to Promote Self-Care of Diabetic Foot Ulcers in Oman
This study aims to evaluate DiaFootCare, a mobile health application designed to support self-care and monitoring among adults with diabetic foot ulcers.
- Trial name
- DiaFootCare (NCT07815275)
- Testing
- DiaFootCare Mobile Application, Usual Diabetic Foot Care
- Where
- Oman
- Volunteers
- 139 people
- Sponsor
- Oman Ministry of Health
Breast Cancer, Breast Neoplasm
Evaluating an AI-Based Mobile Application for Chemotherapy Support in Breast Cancer Patients
The goal of this clinical trial is to learn if an Arabic-language mobile application that uses artificial intelligence (AI) can help women with breast cancer during chemotherapy.
- Conditions
- Breast Cancer, Breast Neoplasm, Chemotherapy-Related Toxicities, Medication Adherence
- Trial name
- AI-ChemoApp (NCT07273812)
- Testing
- AI-Based Mobile Application for Personalized Chemotherapy Support, Usual Care
- Where
- Iraq
- Volunteers
- 130 people
- Sponsor
- Dena h. Al-Tameemi
Statin, Cardiovascular Risk Factors
Role of Coronary CTA on Lipid Management and Risk Factors Control in an Asymptomatic Chinese Population
The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy improves lipid-lowering treatment and cardiovascular risk factor…
- Conditions
- Statin, Cardiovascular Risk Factors, Primary Prevention, Adherence, Medication
- Trial name
- RESPECT2 (NCT05725096)
- Testing
- Coronary Computed Tomography Angiography, Traditional cardiovascular risk stratification
- Where
- China
- Volunteers
- 3,400 people
- Sponsor
- Zhang longjiang,MD
Opioid Use Disorder (OUD), Chronic Pain
Opioid Adherence and Support Through Innovative Texting Strategies
The goal of this clinical trial is to examine the effects of reminder and mindfulness text messages on medication adherence and managing craving, pain, and withdrawal symptoms in people taking medications for opioid use disorder…
- Trial name
- OASIS (NCT07350148)
- Testing
- Mindfulness text messages
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Drug Use Disorders, PrEP Uptake
Reducing Co-occurring Substance Use and HIV Risk Among Stimulant-using Men at High Risk for HIV in the United States of America.
This intervention will focus on stimulant-using men at high risk for HIV who are in need of tailored behavioral interventions to mitigate co-occurring stimulant use and HIV risk in the era of pre-exposure prophylaxis (PrEP).
- Conditions
- Drug Use Disorders, PrEP Uptake, PrEP Adherence, HIV Risk Behavior
- Trial name
- NCT07281378
- Testing
- Tailored Positive Affect Intervention, Contingency Management
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Florida
Heart Failure, Chronic Heart Failure (CHF)
SUPPORT-HEART-PK: Effectiveness, Implementation, and Cost-Effectiveness of a Theory-Based, RE-AIM-Informed Digital Self-Management Intervention for Heart Failure in Pakistan-A Hybrid Type 1 Effectiveness-Implementation Randomized Controlled Trial
Medication non-adherence leads to recurrent admissions, worsening symptoms, poor quality of life, and increased healthcare costs in an already overburdened health system.
- Trial name
- NCT07580508
- Testing
- RE-AIM-informed autonomy-competence intervention
- Where
- Pakistan
- Volunteers
- 870 people
- Sponsor
- Universiti Putra Malaysia
Alcoholic Cirrhosis, Alcohol Abstinence
Safety & Efficacy of Baclofen for Alcohol Withdrawal in Chronic Liver Disease With Active Alcohol Consumption
This study examines the safety and effectiveness of baclofen as a treatment for alcohol withdrawal in patients with chronic liver disease who continue drinking.
- Conditions
- Alcoholic Cirrhosis, Alcohol Abstinence, Alcohol Withdrawal, Medication Toxicity
- Trial name
- BAWIC (NCT06840652)
- Testing
- Baclofen
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Corporacion Parc Tauli