Clinical trials: Medication Administration
Multiple Sclerosis
Adherence to Treatment With Tecfidera™ in Multiple Sclerosis Patients
The investigators are measuring the adherence rates of an oral MS drug that is to be administered twice-daily. The investigators would like to observe any patterns that might indicate factors that greatly affect adherence.
- Trial name
- ADIMS (NCT02099370)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of South Florida
Dermatitis, Atopic
Protopic Ointment in Adult Atopic Eczema of the Face
Patients with facial atopic eczema and a poor response to topical corticosteroid applied either Protopic or Fluticasone ointment twice a day for 3 weeks.
- Trial name
- NCT00690105
- Testing
- tacrolimus 0.1%, fluticasone 0.005 %
- Where
- France
- Volunteers
- 577 people
- Sponsor
- Astellas Pharma Inc
Obesity & Overweight
Trial of Food Is Medicine Approaches for Obesity Treatment in Adults With Food Insecurity
The goal of this clinical trial is to learn if increased access to healthy foods, combined with behavioral weight loss (BWL) interventions, results in greater weight loss for adults with obesity and food insecurity.
- Trial name
- EatWell Rx (NCT07396805)
- Testing
- BWL, VOUCHER, HOME
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Johns Hopkins University
Breast Neoplasms
Attenuating Cancer Treatment-related Toxicity in Oncology Patients With a Tailored Physical Exercise Program
The aim of this study is to determine if therapeutic exercise before anticancer treatment will mitigate the onset or extent of cardiotoxicity comparing to therapeutic exercise performed during anticancer treatment.
- Trial name
- ATOPE (NCT03787966)
- Testing
- ATOPE-B, ATOPE-I
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad de Granada
Dementia, Alzheimer's Disease and Related Dementias
HomeCare Medication Management for People With Dementia
This study will evaluate whether the HomeCare medication management system can improve medication adherence and related outcomes for adults age 65 and older living with dementia, Alzheimer's disease, or related dementias.
- Trial name
- NCT07872072
- Testing
- HomeCare
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- HiDO Technologies
Hypertension, Medication Therapy Management
Efficacy of Pharmacist Interventions Through the "Medication Therapy Management Pathway in Hypertensive Patients"
The goal of this Randomized Controlled Trial is to carry out in adult patients with primary hypertension whose blood pressure control is not up to standard.
- Trial name
- PharmMTMH (NCT06310512)
- Testing
- Structured drug therapy management
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Beijing Anzhen Hospital
Human Papillomavirus Infection, Anogenital Warts
Study of the Efficacy and Safety of the Drug Ingaron (Interferon-gamma) in the Treatment of Anogenital Warts
The primary purpose of this study is to evaluate the effectiveness of destructive therapy for anogenital warts in combination with the use of Ingaron in comparison with destructive therapy.
- Trial name
- ING-HPV-1 (NCT05156541)
- Testing
- Interferon gamma human recombinant (IFN-G)
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- SPP Pharmaclon Ltd.
Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy
MH-Rx Study (Baby on Board: Check-in on You, Your Medication, & Your Blood Pressure)
This randomized controlled trial will evaluate whether adding Community Health Worker (CHW)/Social Worker (SW)-led support for non-medical health related needs (NMHRN) and clinician-led Medication Therapy Management (MTM) to…
- Conditions
- Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy, Gestational Hypertension
- Trial name
- NCT07842341
- Testing
- Community Health Worker (CHW)/Social Worker (SW)-led non-medical health related needs (NMHRN) intervention + Clinician-Led Medication Therapy Management (MTM) with remote blood pressure monitoring, Active Comparator (Control group)
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Texas Southern University
Neoplasms, Carcinoma, Squamous
Nivolumab Combined With Chemotherapy in the Treatment of Primary Tracheal Squamous Cell Carcinoma
This is a single-arm, open, II phase study to evaluate the safety and efficacy of Nivolumab + carboplatin + paclitaxel in 25 newly diagnosed patients with primary tracheal squamous cell carcinoma.
- Conditions
- Neoplasms, Carcinoma, Squamous, Antineoplastic Agents
- Trial name
- GALAXY-1 (NCT05964101)
- Testing
- Nivolumab Injection [Opdivo]
- Where
- China
- Volunteers
- 25 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Alzheimer Disease
A Pilot Study to Reduce Inappropriate Anticholinergic Prescribing in the Elderly
This will be an eight-week, prospective, placebo-controlled, randomized trial to evaluate a patient-centered team (pharmacist-physician) intervention to improve medication appropriateness and reduce the use of inappropriate…
- Trial name
- NCT02172612
- Testing
- Arm 1 Education Session
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Daniela Moga
Palliative Care, Terminal Care
Appropriate Medication Use in Dutch Terminal Care
The AMUSE trial is a multicentre stepped-wedge cluster randomized controlled trial where medication optimization of patients with a life expectancy of less than three months is investigated by using CDSS-OPTIMED (a personalized…
- Conditions
- Palliative Care, Terminal Care, Medication Therapy Management, Clinical Decision Support System (CDSS)
- Trial name
- AMUSE (NCT05351281)
- Testing
- CDSS-OPTIMED
- Where
- 7 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Prof.dr Carin (C.C.D.) van der Rijt
Healthy
Bio-equivalency Study of Moxifloxacin Tablets, 400 mg Under Fasting Conditions
An open label, balanced, randomized, two-treatment, two-period, two-sequence, single dose, crossover, oral bioequivalence study in human subjects under fasting conditions.
- Trial name
- NCT02322619
- Testing
- Moxifloxacin Tablets 400 mg
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Frailty
Nutraceuticals and Drug Treatment in Frail Older Adults
Frailty is a multidimensional condition due to reserve loss leading to physical and cognitive impairment that is very common in older adults; in fact, its incidence increases with age.
- Trial name
- NCT04962841
- Testing
- Nutraceuticals
- Where
- Italy
- Volunteers
- 485 people
- Sponsor
- University of Campania Luigi Vanvitelli
Irritable Bowel Syndrome
Effect of Asimadoline, a Member of a New Medication Class, on Acute Attacks of Pain in Irritable Bowel Syndrome
The treatment of acute pain in patients with irritable bowel symptoms is suboptimal. This is a placebo controlled study of the on demand treatment of pain experienced over a 4 week period in patients with irritable bowel…
- Trial name
- NCT00955994
- Testing
- asimadoline
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Coronary Angiography
Predilation of Side Branch During Percutaneous Treatment of Bifurcation Lesions With Provisional T Stenting
Percutaneous treatment of bifurcation lesion is a complex procedure. After main vessel stent implantation, the side branch became jailed and the carina can be displaced resulting in complete occlusion of this vessel.
- Trial name
- NCT01090856
- Testing
- Pre-dilation side branch
- Where
- Spain
- Volunteers
- 420 people
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Inflammatory Bowel Diseases, Colitis, Ulcerative
A Study on How Vedolizumab is Given and the Outcomes for Adults With Inflammatory Bowel Disease (VARIETY-Belgium)
IBD consists of either ulcerative colitis or Crohn's disease. The main aim of this study is to describe real-world treatment patterns in adults with moderate to severe ulcerative colitis or Crohn's disease when treated with…
- Conditions
- Inflammatory Bowel Diseases, Colitis, Ulcerative, Crohns Disease
- Trial name
- NCT04959851
- Where
- 10 sites in Belgium
- Volunteers
- 185 people
- Sponsor
- Takeda
Opioid Use Disorder, HIV Infections
Medication-assisted Treatment for Injecting Drug Users in Vietnam
HIV continues to spread around the world and new infections in Asia are one of the most important areas for prevention among drug using populations.
- Trial name
- OIT-HCMC (NCT05368675)
- Testing
- medication for opioid use disorder
- Volunteers
- 448 people
- Sponsor
- University of Pennsylvania
Cutaneous Melanoma, Melanoma
A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma
This phase II trial studies the effect of a vaccine called CDX-1401 given with or without a biologic drug called CDX-301 in treating patients with stage IIB-IV melanoma.
- Conditions
- Cutaneous Melanoma, Melanoma, Melanoma of Unknown Primary, Mucosal Melanoma
- Trial name
- NCT02129075
- Testing
- DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Recombinant Flt3 Ligand
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute (NCI)
Rheumatoid Arthritis
Rituximab for the Treatment of Early Rheumatoid Arthritis (RA)
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint swelling, pain, stiffness, damage, and ultimately loss of joint function.
- Trial name
- NCT00396812
- Testing
- Rituximab
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Fibromyalgia Syndrome
Efficacy and Safety of Tongluo-Kaibi Tablet in Patients With Fibromyalgia Syndrome
This study is a multi-center, randomized, double-blinded, controlled trial with two parallel arms. The aim of the study is to evaluate efficacy and safety of Tongluo-Kaibi tablets in patients with Fibromyalgia Syndrome.
- Trial name
- NCT05933486
- Volunteers
- 150 people
- Sponsor
- Quan Jiang