Clinical trials: Medication Assisted Treatment
Depressive Disorder, Bipolar Disorder
PROSPECTIVE EVALUATION OF BLOOD BIOMARKERS AS AN AID TO DIAGNOSTIC AND TREATMENT IN DRUG-NAIVE PATIENTS WITH DEPRESSION
This is an observational (non-interventional) prospective study, carried out in drug-naïve outpatients who start a treatment with escitalopram, fluoxetine, sertraline or quetiapine. Five blood samples are collected (i.e.
- Conditions
- Depressive Disorder, Bipolar Disorder, Bipolar Depression
- Trial name
- NCT06369792
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Les Toises - Psychiatry and Psychotherapy Center
Opioid-use Disorder, Opioid Use
The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis
Pregnant women with a history of opioid use disorder, chronic opioid use or those who are on medication assisted treatment will be randomly assigned to receive either a sub-fascial continuous infusion of bupivacaine or…
- Conditions
- Opioid-use Disorder, Opioid Use, Opioid Dependence, Opioid Abuse
- Trial name
- NCT04033562
- Testing
- Lidocaine patch, Ambu ACTion pump, 0.125% bupivacaine at 8cc/hr
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Pancreatic Ductal Adenocarcinoma, Pain, Acute
Ketamine-assisted Therapy for Advanced GI Cancer
This clinical trial evaluates whether it is possible to use a single dose of ketamine in combination with talk therapy to treat moderate to severe demoralization in patients with stage 3 or 4 gastrointestinal (GI) cancers who…
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pain, Acute, Gastrointestinal Cancers, Demoralization
- Trial name
- NCT06077487
- Testing
- Ketamine, Ketamine Injectable Product, Meaning and Purpose therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Brian Anderson, MD
Opioid-Related Disorders
Trial of Methadone Maintenance Versus Methadone Detox in Jail
Methadone maintenance treatment (MMT) has been shown to be effective in reducing drug use, criminal activity and recidivism. Given this effectiveness, maintaining individuals who are enrolled in community MMT when committed to…
- Trial name
- NCT01874964
- Testing
- Methadone Maintenance, Linkage to methadone maintenance
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- The Miriam Hospital
Opioid Addiction
MEDiterranean Diet-driven Detoxification of OPioid Addicted patiEnts (MED-DOPE)
The MED-DOPE (MEDiterranean diet-driven Detoxification of OPioid addicted patiEnts) study is a randomized controlled trial that aims to investigate the role of a nutritional intervention based on the principles of Mediterranean…
- Trial name
- MED-DOPE (NCT07022782)
- Testing
- A nutritional intervention based on the principles of Mediterranean diet
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristidis Veskoukis
Critical Laboratory Values, Drug Laboratory Interactions
Effect of an Automated Paging System on Response to Critical Laboratory Values
Patients in hospitals may develop serious problems that are detected by blood tests. It is very important for the physicians to be notified of these abnormal blood tests as soon as possible.
- Conditions
- Critical Laboratory Values, Drug Laboratory Interactions, Drug Drug Interactions
- Trial name
- NCT00469924
- Testing
- Real Time Clinical Alerting
- Where
- Canada
- Volunteers
- 271 people
- Sponsor
- Sunnybrook Health Sciences Centre
Depression
Comparative Efficacy of Self-Help Multicomponent Lifestyle Medicine Intervention and Cognitive Behavioral Therapy for Depressive Symptoms
The objective of this proposed pilot randomized controlled trial is to examine the efficacy of self-help multicomponent lifestyle medicine intervention and cognitive behavioral therapy relative to a wait-list control group for…
- Trial name
- NCT05692219
- Testing
- Lifestyle medicine, Cognitive behavioral therapy
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Mental Health Literacy
Web-based Mental Health Literacy Program
Mental health literacy is a concept that aims to improve the skills of individuals to overcome difficulties in providing the appropriate help they need in this area.
- Trial name
- NCT04597996
- Testing
- web based education for students
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Opioid-Related Disorders, Opioid-use Disorder
RETAIN: Retaining Opioid Users Entering Medication Assisted Treatment and Encouraging HCV/HIV Testing
The purpose of this research study is to: 1. assess how well individuals entering medication assisted treatment like the RETAIN e-health application as measured by their feedback on the intervention. 2.
- Conditions
- Opioid-Related Disorders, Opioid-use Disorder, Drug Addiction, Substance Use Disorders
- Trial name
- RETAIN (NCT03411265)
- Testing
- self-administered, e-health application
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Cincinnati
Partner Assisted Interpersonal Psychotherapy, Treatment as Usual
Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression
Purpose: To compare a novel psychotherapy, Partner-Assisted Interpersonal Psychotherapy (PA-IPT), with treatment as usual (TAU) in a sample of pregnant women seeking treatment for Major Depressive Disorder (MDD) at the University…
- Trial name
- NCT01732055
- Testing
- Partner-Assisted Interpersonal Psychotherapy, Treatment as Usual
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Addiction, Opioid-use Disorder
Comprehensive CBT (Cognitive Behavioral Therapy) Via reSET App
This research is being done to find out whether an app based cognitive behavior therapy called reSET improves the adherence to and outcome of buprenorphine treatment for opioid use disorder (OUD) in the setting of a Hub and Spoke…
- Trial name
- NCT03826966
- Testing
- reSET
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Milton S. Hershey Medical Center
Leukaemia, Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma
Randomised Controlled Trial of Artificial Intelligence-assisted Health Education
With the rapid advancement of biopharmaceutical technology, clinical trials have become the crucial bridge connecting new drugs from the laboratory to clinical application.
- Conditions
- Leukaemia, Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma, Lymphoma
- Trial name
- NCT07305337
- Testing
- Artificial Intelligence Health Education, Artificial health education
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Zhongnan Hospital
Obsessive-compulsive Disorder
Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe OCD
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder characterized by recurrent distressing thoughts and substantial anxiety, accompanied by repetitive behaviors or mental rituals.
- Trial name
- NCT04882839
- Testing
- psychotherapy assisted psilocybin
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Beersheva Mental Health Center
Opioid-use Disorder
reSET-O RCT (Randomized Controlled Trial)
This randomized controlled trial research study will be evaluating an app, reSET-O, owned by Pear Therapeutics, Inc., to evaluate treatment retention rates in individuals with opioid use disorder after initiating medication…
- Trial name
- NCT04129580
- Testing
- reSET-O app
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Milton S. Hershey Medical Center
Medication Administered in Error
Detection Medication Administration Errors Using Bar-code and RFID Technology (DREAM)
Serious medication administration errors are common in hospitals. Various interventions were developed to help prevention of such errors such as bar-code technology.
- Trial name
- DREAM (NCT02325336)
- Testing
- BCMA (bar-code-assisted medication administration)
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Opioid Use Disorder
Pilot Test of Patient Decision Aid for Opioid Use Disorder
The aims of the current study phase (R21) are: Aim 1. Develop a patient decision aid (PtDA-MAT) by incorporating best available scientific evidence on MAT as well as feedback from patients and clinical providers related to…
- Trial name
- PtDA-MAT (NCT03394261)
- Testing
- Patient Decision Aid
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Los Angeles
Post-operative Situation
Study of a Prototype Software to Help Surgical Patients Manage Their Pain Medication
The experimental medical device is a prototype software. The device comes in the form of a smartphone with a touch interface. The smartphone used to support the software is a commercial smartphone marked CE.
- Trial name
- MORPHEE 2 (NCT05707247)
- Testing
- software
- Where
- France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Strasbourg, France
Disorders of Consciousness, Vegetative State
AI-Assisted Precision Hyperbaric Oxygen Therapy Based on Dynamic BIS-EEG Feedback for Patients With Disorders of Consciousness
Disorders of consciousness (DoC) are severe neurological conditions characterized by impaired awareness and reduced interaction with the environment.
- Conditions
- Disorders of Consciousness, Vegetative State, Minimally Conscious State
- Trial name
- AI-HBOT-DoC (NCT07855848)
- Testing
- AI-Assisted Personalized Hyperbaric Oxygen Therapy, Conventional Hyperbaric Oxygen Therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Health Education, First Aid
Readiness for Basic Life Support in Schools
This research is a response to problems with Cardiovascular Disease in Colombia, where circulatory system diseases are the first cause of mortality in the adult population, making them a critical issue for the country.
- Conditions
- Health Education, First Aid, Cardiopulmonary Resuscitation
- Trial name
- NCT04914871
- Testing
- Protocol UN Lifeguard Kids in the Tunja version, Educational session accident prevention and wound management
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Educational Problems
Video-Assisted Instruction and Health Education
This research was conducted to examine the effect of video-assisted teaching on the health education skill of midwifery students.
- Trial name
- NCT05984693
- Testing
- Video Assisted Instruction
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Tokat Gaziosmanpasa University