Clinical trials: Medication Non-Adherence
Medication Adherence
Establishing Novel Antiretroviral Imaging for Hair to Elucidate Non-Adherence (ENLIGHTEN)
This is a pilot study to assess the feasibility, acceptability and appropriateness of delivery of the investigational "MedViewer" intervention in adult patients living with HIV who have been prescribed antiretroviral (ARV)…
- Trial name
- ENLIGHTEN (NCT04232540)
- Testing
- MedViewer report
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Medication Adherence
Incidence of Non Adherence to Treatment With Once-daily Formulation of Tacrolimus
Aim The primary objective of this study is to compare medication adherence with medical therapy in patients receiving once-daily versus twice-daily tacrolimus regimens.
- Trial name
- Advagraf (NCT02805842)
- Testing
- Tacrolimus BID, Advagraf QD
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Schizophrenia, Schizo Affective Disorder
Financial Incentives to Improve Acceptance of Antipsychotic Injections
There is a lack of incentive approach for patients who suffer from schizophrenia yet lack the insight to accept treatment. Most existing approaches involve coercion and involuntary hospitalizations.
- Conditions
- Schizophrenia, Schizo Affective Disorder, Bipolar I Disorder
- Trial name
- NCT03192631
- Testing
- Financial incentive
- Volunteers
- 20 people
- Sponsor
- Focus Community Mental Health Team
Primary Care, Health Services Utilization
Study on Primary Care Health Service Utilization in Hong Kong
The aim of this study was to find out the utilization rate and pattern of primary health care services, and the process and outcomes of primary care consultations of the general population in Hong Kong, and whether having a…
- Conditions
- Primary Care, Health Services Utilization, Family Practice
- Trial name
- NCT01422031
- Where
- China
- Volunteers
- 3,148 people
- Sponsor
- The University of Hong Kong
Diabetes Mellitus, Type 2, Hypertension
A Targeted and Tailored Pharmacist Intervention to Improve Adherence to Antihypertensive Drugs Among Diabetes Patients
The primary objective of this study is to assess the effect of a targeted and tailored pharmacist intervention on medication adherence among diabetes patients non-adherent to antihypertensive drugs.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Medication Nonadherence
- Trial name
- NCT04023734
- Testing
- Reminders, habit-based strategies and/or involvement of family member, Counselling to increase knowledge, Counselling to increase motivation
- Where
- Indonesia
- Volunteers
- 113 people
- Sponsor
- University of Groningen
Atrial Fibrillation, Medication Adherence
Use of Electronic Personal Health Records to Improve Medication Adherence
The purpose of this pilot study is to examine the use of a personal health record to improve medication adherence among patients with non-valvular atrial fibrillation taking dabigatran for primary prevention of embolic stroke.
- Trial name
- NCT03018197
- Testing
- Medication Education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Parkview Health
HIV Infections, Depression
Task Shifting to Treat Depression and HIV Medication Nonadherence in Low Resource Settings
A hybrid effectiveness-efficacy trial to evaluate a stepped care task shifted intervention to treat depression and HIV medication nonadherence in low resource settings in rural Zimbabwe.
- Trial name
- NCT04018391
- Testing
- Stepped care for nonadherence and depression, Enhanced Usual Care
- Where
- Zimbabwe
- Volunteers
- 280 people
- Sponsor
- King's College London
HIV/AIDS
Effectiveness of Intensive Adherence Counselling Among People Living With HIV/AIDS With Low-level Viraemia in Uganda.
Uganda uses a threshold of 1,000 copies/ml to determine HIV viral non-suppression among people living with HIV/AIDS (PLHIV) on treatment, which is indicative of either poor adherence or HIV virologic treatment failure; as per the…
- Trial name
- NCT05514418
- Testing
- Intensive Adherence Counselling (IAC)
- Where
- 8 sites in Uganda
- Volunteers
- 136 people
- Sponsor
- Makerere University
Adherence, Medication
Prevalence and Determinants of Therapeutic Non-Compliance in Patients With Chronic Pathologies ( PDTNCCP)
Identify the prevalence and determinants related to therapeutic non adherence among patients with chronic pathologies and to design effective interventions optimizing treatment compliance.
- Trial name
- PDTNCCP (NCT07864532)
- Where
- Tunisia
- Volunteers
- 3,000 people
- Sponsor
- University of Monastir
Diabetes, Hypertension
A Spanish Pillbox App for Elderly Patients Taking Multiple Medications
Background: Non-adherence and medication errors are common among patients with complex drug regimens. Applications for smartphones and tablets are known to be effective for improving adherence but they have not been tested in…
- Trial name
- ALICE (NCT02071498)
- Testing
- Pillbox app named ALICE, oral and written information
- Where
- Spain
- Volunteers
- 99 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Healthy
Gastroprotective Agent Utilization and Compliance in Elderly Patients Taking Non-steroidal Anti-inflammatory Drug (NSAID) in France
The purpose of this study is to assess in general population NSAID and gastroprotective agent utilization and compliance in elderly people.
- Trial name
- NCT01211652
- Where
- 3,510 sites in France
- Volunteers
- 8,186 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Hypertension, Primary Hypertension
Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs Intake
By conducting the SPPA trial we try to find out, whether personalized Short Message Service (SMS) reminders of blood pressure-lowering medication can effectively increase patients' adherence to blood pressure-lowering medication.
- Conditions
- Hypertension, Primary Hypertension, Non-Adherence, Medication, Non-Adherence, Patient
- Trial name
- SPPA (NCT03105687)
- Testing
- SMS reminders of medicines intake
- Where
- 24 sites in Slovakia
- Volunteers
- 300 people
- Sponsor
- Comenius University
Heart Failure
Study of Reminding to Improve Medication Adherence in Heart Failure
This study is being done to look at how people manage their heart failure. The investigators are testing two medication reminder systems and the investigators want to know which one people like better.
- Trial name
- Heart iRx (NCT01463267)
- Testing
- iPhone or pillbox, Non-reminding
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kent State University
Metastatic Renal Cancer, Stage III Renal Cell Cancer
Safety and Compliance of Renal Cancer Patients Treated by Non-IV Drugs
Generally, in the trials, an observant patient is described as correctly taking 90 to 100% of the prescribed doses. Here, the 80% compliance rate will be the cut-off between observant and non-observant patients.
- Trial name
- TOPTACOS (NCT03630692)
- Testing
- observance of oral drug treatment
- Where
- 14 sites in France
- Volunteers
- 158 people
- Sponsor
- Institut Cancerologie de l'Ouest
Epilepsy
IMPACT of AspireSR® for VNS Therapy on Healthcare Resource Utilisation and Clinical Outcomes.
This is a retrospective non-interventional study to describe the HCRU and clinical outcomes before and after AspireSR® device implantation in subjects with drug resistant epilepsy at the Queen Elizabeth Hospital, Birmingham…
- Trial name
- IMPACT (NCT05975931)
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- LivaNova
Diabetes Mellitus, Non-Insulin-Dependent
Education and Group Support for Diabetic Hispanics
The purpose of this ongoing work in Starr County, located on the Texas-Mexico border, is to conduct clinical studies to determine the effectiveness of diabetes self-management programs designed specifically for Mexican Americans.
- Trial name
- NCT00004983
- Testing
- diabetes self-management education
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type2 Diabetes, Medication Adherence
Improving Diabetes Medication Adherence for African Americans in Madison and Milwaukee Through Peer Support
The burden of diabetes is higher among African Americans (AAs) in Wisconsin as hospitalization rates for diabetes complications such as stroke and amputations are four times higher than whites and has worsened by 334% since 2011.
- Conditions
- Type2 Diabetes, Medication Adherence, Medication Nonadherence, Peer Support
- Trial name
- NCT04028076
- Testing
- Peers Supporting Health-Literacy, Self Efficacy, Advocacy and Adherence
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Kidney Transplantation, Medication Non-Adherence
Kidney Transplant Immunosuppressive Therapy Adherence Trial (KITE)
This randomized controlled interventional study aims to evaluate the effect of structured education and telephone counseling on immunosuppressive medication adherence among kidney transplant recipients.
- Conditions
- Kidney Transplantation, Medication Non-Adherence, Immunosuppressive Therapy, Renal Transplant Recipients
- Trial name
- KITE (NCT07364123)
- Testing
- Education and Telephone Counseling Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Gaziantep
Asthma in Children, Nonadherence, Medication
Symptom-driven ICS/LABA Therapy for Adolescent Patients With Asthma Non-adherent to Daily Maintenance Inhalers
Inhaler nonadherence is a common problem that has been estimated to account for approximately 60% of all asthma-related hospitalizations.
- Trial name
- NCT05689983
- Testing
- Maintenance ICS and Symptom Driven SABA, Symptom-driven budesonide/formoterol combination
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Washington University School of Medicine
Parkinson Disease
Study of Comprehension and Execution of Medication Prescriptions in Parkinsonian Patients and Healthy Volunteers
Many patients with Parkinson's disease (Pd) don't respect medication prescriptions. Non-adherence is caused by several factors among which three play an important role: treatment complexity, cognitive decline, and…
- Trial name
- TACTIPARK (NCT03976505)
- Testing
- reading a table format prescription on a touch screen, reading a textual format prescription on a touch screen, filling a virtual pillbox displayed on the screen as prescribed in the prescription
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens