Clinical trials: Medication Non-Adherence
Hiv, HIV/AIDS
AllyQuest Adherence App Intervention for HIV-positive Men Who Have Sex With Men and Transgender Women: Pilot Trial
AllyQuest (AQ) is a theory-informed smart phone application that supports HIV medication adherence for young men who have sex with men and young transgender women who have sex with men (YMSM/YTW) via behavior change, social…
- Conditions
- Hiv, HIV/AIDS, Medication Adherence, Sexual Behavior
- Trial name
- AQ2 (NCT03916484)
- Testing
- AllyQuest HIV Medication Adherence app-delivered intervention, AllyQuest HIV Medication Adherence app-delivered intervention + NSC
- Where
- 6 sites in United States
- Volunteers
- 71 people
- Sponsor
- University of North Carolina, Chapel Hill
Attention Deficit Disorder, Attention Deficit Disorder (ADD)
The Primary Objective of This Study is to Determine Whether Positively Framed Information (PFI) on Side Effects, Compared to Negatively Framed and Extensive Information (NFI) Can Reduce the Number and Severity of Reported Adverse Events Caused by ADHD Medication in Children Aged 7 to 17 Years.
The goal of this randomized controlled care evaluation is to determine whether positively framed and concise information (PFI), compared to negatively framed and extensive information (NFI) about adverse events can reduce the…
- Conditions
- Attention Deficit Disorder, Attention Deficit Disorder (ADD), Attention Deficit Disorder with Hyperactivity, ADHD
- Trial name
- NOVA (NCT06797570)
- Testing
- Communication Strategy for Side Effect Counseling in ADHD Treatment
- Volunteers
- 130 people
- Sponsor
- St. Antonius Hospital
Musculoskeletal Diseases, Rheumatoid Arthritis
Improving Beliefs About Medication in Patients With Rheumatoid Arthritis
The purpose of this study is to determine if a short motivational patient-centered intervention for non-adherent patients is more successful in improving beliefs about medication (and adherence) compared to a usual care control…
- Trial name
- NCT00968266
- Testing
- Patient-centered group intervention
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Sint Maartenskliniek
Diabetes Mellitus, Chronic Obstructive Pulmonary Disease
Validation of Medication Non-adherence Model (UK)
Research has shown that nearly 50% of patients with chronic conditions around the globe do not adhere to their prescribed medicine, leading to enormous cost to the healthcare providers.
- Conditions
- Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, Chronic Illness, Primary Care
- Trial name
- NCT02115412
- Where
- 4 sites in United Kingdom
- Volunteers
- 750 people
- Sponsor
- Philips Healthcare
Lung Cancer, Medication Adherence
Implementation Strategies for Monitoring Adherence in Real Time
The objective of this project is to identify effective strategies to help patients with lung cancer manage side effects and achieve optimal adherence to oral targeted therapies.
- Conditions
- Lung Cancer, Medication Adherence, Symptoms and Signs
- Trial name
- iSMART (NCT04347161)
- Testing
- Conversational Agent/Chatbot, Usual Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Multiple Sclerosis, Relapsing-Remitting
Delayed Diagnosis of Multiple Sclerosis, Treatment Initiation and Non-adherence in Upper Egypt
The earlier that MS can be diagnosed; the sooner treatment can be initiated with timely reduction of subclinical disease activity and prevention of disability progression.
- Trial name
- NCT05438693
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- doaa mokhtar mahmoud
Bipolar Disorder, Non-Adherence, Medication
Using mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Mood Disorders
This proposed 2-stage randomized controlled trial (RCT) will evaluate a personalized patient-centered adherence intervention iTAB-CV + Self-Monitoring (iTAB-CV + SM) vs.
- Conditions
- Bipolar Disorder, Non-Adherence, Medication, Hypertension, Major Depressive Disorder
- Trial name
- iTAB-CV RCT (NCT04675593)
- Testing
- iTAB-CV, Self-Monitoring
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Case Western Reserve University
Schizophrenia; Psychosis, Remission
Effects of an Interpersonal Communication Skills Training Program on Medication Adherence of Schizophrenic Patients
This quasi-experimental two-group pretest-posttest study examined the effects of an interpersonal communication skills training program on medication adherence in patients with schizophrenia, measured at pre-intervention…
- Conditions
- Schizophrenia; Psychosis, Remission, Non-Adherence, Medication
- Trial name
- NCT07165821
- Testing
- Interpersonal Communication Skills Training Program, Usual care
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Suranaree University of Technology
Medication Non Adherence, Polypharmacy
Tailored Medication Management Intervention
Successful medication management is an essential instrumental activity of daily living (IADL) for older adults with polypharmacy; however, between 40%-70% of older adults fail to take their medications as prescribed.
- Trial name
- NCT04717297
- Testing
- Medication Management Remote Intervention, Waitlist Control, Medication Management In-Person Intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Washington University School of Medicine
Heart Transplant Rejection, Immune Suppression
Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients
We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR)…
- Conditions
- Heart Transplant Rejection, Immune Suppression, Pediatric Heart Transplant, Medication Nonadherence
- Trial name
- NCT05732779
- Testing
- DOT intervention
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Breast Neoplasms, Prostatic Neoplasms
Study to Investigate Adherence of Patients to Clodronate (Bonefos) Treatment
Adherence (or compliance with) a medication regimen is generally defined as the extent to which patients take medication as prescribed by their health care providers.
- Conditions
- Breast Neoplasms, Prostatic Neoplasms, Multiple Myeloma, Osteolysis
- Trial name
- BONA (NCT01198457)
- Testing
- Clodronate (Bonefos, BAY94-8393)
- Where
- Czechia
- Volunteers
- 147 people
- Sponsor
- Bayer
Soil-transmitted Helminth Infections
Community Health Education and Hygiene Promotion Added to Deworming Among Ethnic Khmer Children in Vietnam
This study evaluated whether adding community health education and household hygiene promotion to supervised deworming could improve soil-transmitted helminth (STH) outcomes and related caregiver and household factors among…
- Trial name
- NCT07855978
- Testing
- Albendazole 400 mg, Community Health Education and Hygiene Promotion
- Where
- 4 sites in Vietnam
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Femoropopliteal Disease, Drug Coated Balloon
DCB Outcomes After Non-Compliant Balloon Vessel Preparation With or Without Scoring in Patients With Femoropopliteal Arterial Disease
The aim of this clinical trial is to determine whether vessel preparation with a non-compliant scoring balloon before drug-coated balloon (DCB) angioplasty provides superior procedural and clinical outcomes compared with vessel…
- Conditions
- Femoropopliteal Disease, Drug Coated Balloon, Critical Limb-Threatening Ischaemia, Peripheral Arterial Disease
- Trial name
- DASBAD-NC (NCT07764016)
- Testing
- Non-compliant Plain Balloon angioplasty (PBA), Non-compliant Scoring Balloon Angioplasty (SB)
- Volunteers
- 142 people
- Sponsor
- Marc Sirvent
Medication Non-adherence
Improving Adherence and Outcomes by Artificial Intelligence-Adapted Text Messages
Uncontrolled hypertension is a major cause of morbidity and mortality and many patients fail to take their antihypertensive medication as prescribed.
- Trial name
- AIM@BP (NCT02454660)
- Testing
- SMS (Text messages)
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Medication Non-adherence, Stent Thrombosis
Patterns of Non-Adherence to Dual Anti-Platelet Regimen In Stented Patients
The purpose of this observational research study is to determine when and why patients discontinue, interrupt, or disrupt the regimen of anti-platelet medications prescribed following stent implantation, and to examine the…
- Trial name
- PARIS (NCT00998127)
- Where
- 15 sites in United States, France and 3 more
- Volunteers
- 5,031 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Osteoarthritis, Rheumatoid Arthritis
Observational Study on Non-steroid Anti-inflammatory Drugs (NSAIDs) Treated Patients With Arthritic Disorder
The aim of this study is to find out how patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis receiving NSAID-therapy are treated and managed by their doctor in usual clinical practice, how patients…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- EVIDENCE (NCT01176682)
- Where
- 244 sites in Belgium, France and 10 more
- Volunteers
- 1,149 people
- Sponsor
- AstraZeneca
Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome
HIV Medication Adherence in Underserved Populations
The purpose of this study is to determine whether cognitive rehabilitation or psychoeducation impacts medication adherence in HIV-1 seropositive individuals.
- Trial name
- NCT02392884
- Testing
- Cognitive Rehabilitation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Cystic Fibrosis, Hemophilia A
Medication Adherence and Non-adherence in Adults With Rare Disease
The purpose of this study is to use the Medication Adherence Reasons Scale (MAR-Scale) to determine the extent of non-adherence to specific medications indicated to treat cystic fibrosis, hemophilia (A or B), idiopathic pulmonary…
- Conditions
- Cystic Fibrosis, Hemophilia A, Hemophilia B, Idiopathic Pulmonary Fibrosis
- Trial name
- NCT04541875
- Testing
- MAR-Scale
- Volunteers
- healthy volunteers welcome
- Sponsor
- Xperiome
Diabetes, Medication Non Adherence
Influence of Pharmacist and Student Pharmacists on Medication Adherence in Community Pharmacy Setting in Underserved Population
The overall objective is to examine the influence of various services provided by the community pharmacy on patients' diabetes and diabetes-related health outcomes.
- Conditions
- Diabetes, Medication Non Adherence, Blood Pressure, Pharmacist-Patient Relations
- Trial name
- NCT04376112
- Testing
- Pharmacist and pillpack intervention, Standard of care
- Where
- United States
- Sponsor
- Loma Linda University
Medication Adherence, Medication Nonadherence
Determining the Impact of a Medication Delivery Unit on Medication Adherence of Adults With Common Cardiac Conditions
The research study is a randomized controlled trial (RCT). The primary endpoint is to compare medication adherence of adult patients recently hospitalized with a diagnosis of common cardiac conditions who require medication…
- Conditions
- Medication Adherence, Medication Nonadherence, Adverse Reaction to Drug
- Trial name
- EMMA-RCT (NCT01600677)
- Testing
- Computerized medication delivery unit, Usual care
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Pittsburgh