Clinical trials: Medication Non-Adherence
Adherence to Medication Regime, Hypertensive Disease
Study for the Recording of Adherence to Treatment With Perindopril/Indapamide/Amlodipine Fixed Dose Combination
The main objective of this study is to record, in routine clinical practice, patients' adherence to treatment with Perindopril/Indapamide/Amlodipine fixed dose combination, during 4 months treatment.
- Trial name
- CONTROL-3 (NCT02655029)
- Testing
- Perindopril/Indapamide/Amlodipine fixed dose combination
- Where
- Greece
- Volunteers
- 2,285 people
- Sponsor
- Servier Hellas Pharmaceuticals Ltd.
Adverse Drug Event, Non-Adherence, Medication
Evaluating ActionADE on Adverse Drug Event Due to Non-Adherence
Repeat non-adherence to medications is a common cause of preventable adverse drug events. Health information technologies have the potential to improve information continuity.
- Trial name
- NCT04574648
- Testing
- ActionADE
- Volunteers
- 2,000 people
- Sponsor
- University of British Columbia
Alcohol Dependence, Alcohol Use Disorder
Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Our primary aim is to assess the feasibility of initiating treatment in the ED with extended-release naltrexone (XR-NTX) plus care management (CM) vs.
- Trial name
- NCT02445339
- Testing
- XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Hypertension, Medication Non-Adherence
Patient Centered Health Technology Medication Adherence Program for African American Hypertensives
This will be a two--arm Randomized controlled trial (RCT) design that will assess efficacy of the Smartphone Medication Adherence Stops Hypertension (SMASH) mobile health ( mHealth) program compared to an enhanced standard care…
- Trial name
- SMASH (NCT03454308)
- Testing
- SMASH, Enhanced SC
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Medical University of South Carolina
Drug Dependence
Drug Use During Sex and Its Impact on Taking PrEP (Pre-Exposure Prophylaxis) : CONSUME
This is a cross-sectional, single-center observational study conducted from October 2020 to March 2021 in Ile de France at the infectious disease of CHU Bichat (PrEP and CeGIDD(Free Center for Information, Screening and Diagnosis…
- Trial name
- CONSUME (NCT04709016)
- Testing
- self-questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Drug Resistance
Aspirin and Clopidogrel Resistance Study
Resistance to antiplatelet drugs (aspirin, clopidogrel) is a recognized phenomenon with a prevalence from 17% to 35%. Resistance as detected by in vitro tests such as Multiple Electrode Aggregometry (MEA) has been shown to…
- Trial name
- NCT01039480
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University Hospital, Basel, Switzerland
Type 2 Diabetes
Vildagliptin Versus Liraglutide - Patient Preference After Receiving Both Medications
Dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagonlike peptide-1 (GLP-1) mimetics or analogs, which rely on the gastrointestinal hormones that are part of the incretin system for the treatment of T2DM, provide a therapeutic…
- Trial name
- PREFER (NCT01518101)
- Testing
- Vildagliptin/ Metformin, Liraglutide, Metformin
- Where
- 8 sites in Germany
- Volunteers
- 62 people
- Sponsor
- Novartis Pharmaceuticals
Multiple Sclerosis, Relapsing-Remitting
A Study of Multiple Sclerosis Routine Clinical Practice: Impact on Adherence and Clinical Outcomes of Ofatumumab Treated Patients
This was a retrospective non-interventional study (NIS) of adult (≥18 years) multiple sclerosis (MS) patients on ofatumumab therapy in the United Kingdom (UK) using secondary data.
- Trial name
- NCT06897657
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes Mellitus, Type 2, Hypertension
An Analysis to Assess Non-adherence in People With Type 2 Diabetes
Non-adherence is defined as: "the extent to which a person's behaviour - taking medication, following a diet, and/or executing lifestyle changes, corresponds with agreed recommendations from a health care provider".
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Medication Adherence
- Trial name
- NCT05256875
- Testing
- chemical adherence test, medication adherence questionnaire, pharmacy refill rate
- Where
- 2 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Leicester
Health Education
Clinical Guidance for Proper Treatment of Unexplained Resistant Hyperprolactinemia.
Many women despite being well-treated in proper dose, with proper drug and for proper duration, may not respond to different forms of prolactin normalizing drugs.
- Trial name
- NCT04262024
- Testing
- cabergoline 1.5-2 mg/week).orally daily for 1 month plus health education, cabergoline 1.5-2 mg/week).orally daily for 1 month without health education
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Woman's Health University Hospital, Egypt
Medication Adherence
Non-adherence to Immunosuppressives in Kidney Transplantation in Brazil Multicenter Study
The purpose of the study are: 1. To estimate the prevalence of non-adherence to immunosuppressants, and to other treatment-related aspects (smoking cessation, alcohol consumption, physical activity, and appointment keeping), in…
- Trial name
- ADHEREBRAZIL (NCT02066935)
- Testing
- kidney transplant patient
- Where
- Brazil
- Volunteers
- 1,105 people
- Sponsor
- Fundação Instituto Mineiro de Estudo Pesquisa Em Nefrologi
Arterial Hypertension, Medication Nonadherence
Feasibility of a Program on a Nurse-led Telephone 6-month-follow-up for Uncontrolled Hypertensive Women
This study evaluate the feasibility of a 6-month personalized support program for hypertensive and non-observant women, led by nurses by telephone follow-up.
- Trial name
- PreDynamiques (NCT03963934)
- Testing
- Program on a nurse-led telephone 6-month-follow-up for uncontrolled hypertensive women: a patient-tailored intervention
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Mme Edith DAUCHY
Bipolar Disorder
Personal Adherence Evaluation of Medication Use for Adult Bipolar Disorder Patients
This study will attempt to increase understanding of why bipolar disorder patients do or do not take their medications by conducting in-depth interviews with them.
- Trial name
- NCT00763581
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Western Reserve University
Steatohepatitis, Nonalcoholic, Steatosis
Nutritional Intervention IN Nash NON-ALCOHOLIC (NAFLD).
The goal of this randomized clinical trial with adults is to discuss the effectiveness of the nutritionist's educational interventions in users diagnosed with NAFLD, compared to the usual medical follow-up of users treated at the…
- Conditions
- Steatohepatitis, Nonalcoholic, Steatosis, Liver Diseases, Steatohepatitis
- Trial name
- NUTRINAFLD (NCT05946330)
- Testing
- NUTRITIONAL EDUCATIONAL INTERVENTION IN FATTY LIVER DISEASE NON-ALCOHOLIC (NAFLD).
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Universidade Federal do Paraná
Chronic Heart Failure With Reduced and Mildly Reduced Ejection Fraction (HFrEF and HFmrEF)
Polypharmacy, Safety, and Medication Adherence in Patients With Chronic Heart Failure With Reduced and Mildly Reduced Ejection Fraction
This prospective registry study (FARAON) aims to assess the prevalence, structure, safety profile, and dynamics of polypharmacy, as well as its association with medication adherence, quality of life, and clinical outcomes in…
- Trial name
- FARAON (NCT07640854)
- Where
- Russia
- Volunteers
- 130 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Opiate Addiction, Medication Non-adherence
Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy
This study uses an artificial intelligence platform to automatically confirm medication ingestion. The Health Insurance Portability and Accountability Act (HIPAA)-compliant platform can be downloaded as an 'app' onto any…
- Conditions
- Opiate Addiction, Medication Non-adherence, Addiction, Opioid Dependence
- Trial name
- NCT02243670
- Testing
- AiCure monitoring and intervention
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- AiCure
Bipolar Disorder, Medication Adherence
CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL)
This is a prospective study using customized adherence enhancement (CAE) and long-acting injectable (LAI) antipsychotic in 30 individuals with bipolar disorder (BD) at risk for treatment non-adherence.
- Conditions
- Bipolar Disorder, Medication Adherence, Medication Non Adherence
- Trial name
- NCT03408873
- Testing
- Abilify Maintena, Customized Adherence Enhancement (CAE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Martha Sajatovic
Patient Satisfaction, Extracorporeal Shock Wave Lithotripsy
COMPARİSON OF THE EFFECTS OF ULTRASOUND-GUİDED ERECTOR SPİNAE PLANE BLOCK AND INTRAMUSCULAR NONSTEROİDAL ANTİ-INFLAMMATORY DRUG ADMİNİSTRATİON ON INTRAOPERATİVE ANALGESİA AND PATİENT SATİSFACTİON DURİNG EXTRACORPOREAL SHOCK WAVE LİTHOTRİPSY
The aim of this study is to compare two ways of reducing pain during extracorporeal shock wave lithotripsy (ESWL), a non-invasive treatment that breaks up kidney and urinary stones with shock waves.
- Conditions
- Patient Satisfaction, Extracorporeal Shock Wave Lithotripsy, Erector Spinae Plane Block
- Trial name
- NCT07880535
- Testing
- Ultrasound-guided erector spinae plane block, Diclofenac Sodium (DCS)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Medication Adherence, End Stage Renal Failure on Dialysis
Prevalence of Non-adherence to Medication Among Patients on Chronic Hemodialysis
Background: Non-adherence to medication among patients on chronic hemodialysis compromises treatment effects and results in increased morbidity, mortality and extensive costs to the healthcare system.
- Trial name
- NCT03897231
- Testing
- questionnaire
- Where
- Denmark
- Volunteers
- 385 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Medication Adherence, Medication Nonadherence
Collaborative Nurse-pharmacist Counseling for Self-administered Biologics
The goal of this clinical trial is to learn if nurse-pharmacist counseling can improve patient knowledge and confidence and prevent side effects in patients who start a biologic medication in-office and later continue the…
- Conditions
- Medication Adherence, Medication Nonadherence, Adverse Drug Event
- Trial name
- COLLAB (NCT05798104)
- Testing
- Collaborative nurse-pharmacist counseling
- Where
- United States
- Sponsor
- Tonia Carr