Clinical trials: Medication Non-adherence
Adherence, Medication
Alterations in the Vaginal Microenvironment Using a Non-pharmacological Intervention
Breast cancer patients commonly take medications to reduce the risk of recurrence, including aromatase inhibitors (AIs). AIs can cause significant side effects that reduce patient adherence.
- Trial name
- NCT03739983
- Testing
- Vaginal Renewal Program
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Wisconsin, Madison
Hiv, HIV/AIDS
AllyQuest Adherence App Intervention for HIV-positive Men Who Have Sex With Men and Transgender Women: Pilot Trial
AllyQuest (AQ) is a theory-informed smart phone application that supports HIV medication adherence for young men who have sex with men and young transgender women who have sex with men (YMSM/YTW) via behavior change, social…
- Conditions
- Hiv, HIV/AIDS, Medication Adherence, Sexual Behavior
- Trial name
- AQ2 (NCT03916484)
- Testing
- AllyQuest HIV Medication Adherence app-delivered intervention, AllyQuest HIV Medication Adherence app-delivered intervention + NSC
- Where
- 6 sites in United States
- Volunteers
- 71 people
- Sponsor
- University of North Carolina, Chapel Hill
Atrial Fibrillation, Medication Adherence
Keep it SIMPLE: Improving Anti-Coagulation Medication Adherence
This is an interventional study designed to develop patient focused strategies that improve adherence to anticoagulant medication in patients with non-valvular atrial fibrillation (AF).
- Trial name
- NCT02690649
- Testing
- Health Messaging (Non-Procedural)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Tammy Toscos
CHF - Congestive Heart Failure
Digital Outreach for Heart Failure Adherence
The goal of the ADHERE-HF study is to evaluate whether care-embedded, operationally delivered digital outreach improves medication refill, adherence, and clinical outcomes among adults with heart failure who are overdue for a…
- Trial name
- ADHERE-HF (NCT07831538)
- Testing
- Digital Outreach
- Where
- United States
- Volunteers
- 13,714 people
- Sponsor
- Kaiser Permanente
Compliance, Gastroprotector Therapy
Adherence to Gastro-protection in Non-steroidal Anti-inflammatory Drug (NSAID) Using Patients
Prospective multicentric study to evaluate the compliance of gastroprotective treatment in NSAID patients at risk of GI complications.
- Conditions
- Compliance, Gastroprotector Therapy, Risk Factors
- Trial name
- GADES (NCT00699725)
- Where
- 128 sites in Spain
- Volunteers
- 2,000 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Chronic Obstructive Pulmonary Disease
Validation of Medication Non-adherence Model (UK)
Research has shown that nearly 50% of patients with chronic conditions around the globe do not adhere to their prescribed medicine, leading to enormous cost to the healthcare providers.
- Conditions
- Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, Chronic Illness, Primary Care
- Trial name
- NCT02115412
- Where
- 4 sites in United Kingdom
- Volunteers
- 750 people
- Sponsor
- Philips Healthcare
Schizophrenia; Psychosis, Remission
Effects of an Interpersonal Communication Skills Training Program on Medication Adherence of Schizophrenic Patients
This quasi-experimental two-group pretest-posttest study examined the effects of an interpersonal communication skills training program on medication adherence in patients with schizophrenia, measured at pre-intervention…
- Conditions
- Schizophrenia; Psychosis, Remission, Non-Adherence, Medication
- Trial name
- NCT07165821
- Testing
- Interpersonal Communication Skills Training Program, Usual care
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Suranaree University of Technology
Type2 Diabetes, Medication Adherence
Improving Diabetes Medication Adherence for African Americans in Madison and Milwaukee Through Peer Support
The burden of diabetes is higher among African Americans (AAs) in Wisconsin as hospitalization rates for diabetes complications such as stroke and amputations are four times higher than whites and has worsened by 334% since 2011.
- Conditions
- Type2 Diabetes, Medication Adherence, Medication Nonadherence, Peer Support
- Trial name
- NCT04028076
- Testing
- Peers Supporting Health-Literacy, Self Efficacy, Advocacy and Adherence
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Asthma
Effects of the Kata® Inhalations-App on Inhaler Handling Errors, Adherence, and Asthma Control in Patients With Asthma.
The Kata® App is a digital therapy assistant for patients with asthma who need to inhale their therapy. Kata features inhalation trainers that shows patients in a simple and understandable way how to improve their inhalation…
- Trial name
- NCT06178341
- Testing
- Kata Inhalations-App
- Where
- 13 sites in Germany
- Volunteers
- 146 people
- Sponsor
- VisionHealth GmbH
Lung Cancer, Medication Adherence
Implementation Strategies for Monitoring Adherence in Real Time
The objective of this project is to identify effective strategies to help patients with lung cancer manage side effects and achieve optimal adherence to oral targeted therapies.
- Conditions
- Lung Cancer, Medication Adherence, Symptoms and Signs
- Trial name
- iSMART (NCT04347161)
- Testing
- Conversational Agent/Chatbot, Usual Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Diabetes, Diabete Type 2
Use of a Smart-phone Based Medication Adherence Platform to Improve Outcomes in Uncontrolled Non-insulin Dependent Diabetes Among Veterans
The purpose of this study is to determine if a novel smartphone-based medication adherence platform accompanied by directed pharmacist intervention can improve A1c control and medication compliance in non-insulin dependent…
- Trial name
- NCT05789706
- Testing
- Dayamed Arthur a novel intelligent medication adherence platform
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Sierra Nevada Health Care System
Bipolar Disorder, Schizophrenia
Event Marker Ingested To Trigger Event Recorder 3.0 Psychiatry Study
Feasibility study of using a digital health feedback system (DHFS) to monitor medication-taking and physiologic and behavioral parameters in patients with bipolar disorder or schizophrenia.
- Trial name
- EMITTER3PSY (NCT01804257)
- Testing
- Digital Health Feedback System
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Proteus Digital Health, Inc.
Pain, Postoperative, Analgesics, Opioid
Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy
A blinded randomized control trial in living kidney donors. The study group will receive a liposomal bupivacaine Trans Quadratus Lumborum (TQL) block after the induction of general anesthesia.
- Conditions
- Pain, Postoperative, Analgesics, Opioid, Analgesics, Non-Narcotic, Physiological Effects of Drugs
- Trial name
- NCT03294109
- Testing
- Abdominal wall block with liposomal bupivicaine
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Adverse Drug Event, Non-Adherence, Medication
Evaluating ActionADE on Adverse Drug Event Due to Non-Adherence
Repeat non-adherence to medications is a common cause of preventable adverse drug events. Health information technologies have the potential to improve information continuity.
- Trial name
- NCT04574648
- Testing
- ActionADE
- Volunteers
- 2,000 people
- Sponsor
- University of British Columbia
Hypertension, Primary Hypertension
Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs Intake
By conducting the SPPA trial we try to find out, whether personalized Short Message Service (SMS) reminders of blood pressure-lowering medication can effectively increase patients' adherence to blood pressure-lowering medication.
- Conditions
- Hypertension, Primary Hypertension, Non-Adherence, Medication, Non-Adherence, Patient
- Trial name
- SPPA (NCT03105687)
- Testing
- SMS reminders of medicines intake
- Where
- 24 sites in Slovakia
- Volunteers
- 300 people
- Sponsor
- Comenius University
Atrial Fibrillation, Medication Adherence
Determination of Rates and Reasons for Non-Adherence to Anti-Arrhythmic Therapy for Atrial Fibrillation
The purpose of this study is to determine if follow-up by a pharmacist over the telephone improves adherence and short term clinical outcomes in the patient with atrial fibrillation prescribed an oral anti-arrhythmic medication.
- Trial name
- NCT01513031
- Testing
- Education and telephone follow-up
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Creighton University
Frozen Shoulder, Depression
Non-adherence to Pain Medication Increases Risk of Postoperative Frozen Shoulder
Background: Postoperative Frozen-Shoulder (FS) or adhesive capsulitis is a relatively frequent complication (5-20%), even after simple arthroscopic shoulder surgeries.
- Trial name
- NaFS (NCT04758585)
- Testing
- Arthroscopy
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Baden
Patient Satisfaction, Extracorporeal Shock Wave Lithotripsy
COMPARİSON OF THE EFFECTS OF ULTRASOUND-GUİDED ERECTOR SPİNAE PLANE BLOCK AND INTRAMUSCULAR NONSTEROİDAL ANTİ-INFLAMMATORY DRUG ADMİNİSTRATİON ON INTRAOPERATİVE ANALGESİA AND PATİENT SATİSFACTİON DURİNG EXTRACORPOREAL SHOCK WAVE LİTHOTRİPSY
The aim of this study is to compare two ways of reducing pain during extracorporeal shock wave lithotripsy (ESWL), a non-invasive treatment that breaks up kidney and urinary stones with shock waves.
- Conditions
- Patient Satisfaction, Extracorporeal Shock Wave Lithotripsy, Erector Spinae Plane Block
- Trial name
- NCT07880535
- Testing
- Ultrasound-guided erector spinae plane block, Diclofenac Sodium (DCS)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Hypertension
Medication Adherence Improvement Support App For Engagement - Blood Pressure
The purpose of this study is to evaluate the impact of the Medisafe smartphone application on blood pressure control and self-reported medication adherence for patients with uncontrolled blood pressure.
- Trial name
- MedISAFE-BP (NCT02727543)
- Testing
- Medisafe
- Where
- United States
- Volunteers
- 413 people
- Sponsor
- Brigham and Women's Hospital
Type 2 Diabetes Mellitus, Medication Adherence
STUDIIO-Diabetes Pilot: STUdy of Drug Insurance to Improve Outcomes of Diabetes
Canada is the only country with a universal health insurance system that does not provide coverage for prescription drugs to all residents. One-third of working-age Canadians have no insurance.
- Conditions
- Type 2 Diabetes Mellitus, Medication Adherence, Medication Compliance, Medication Nonadherence
- Trial name
- NCT03804905
- Testing
- No-cost Medications
- Volunteers
- 144 people
- Sponsor
- Sunnybrook Health Sciences Centre