Clinical trials: Medication Reviews
Healthy
Scopolamine Patch Pharmacokinetics in Healthy Adults
The study to be performed will utilize already FDA-approved marketed products in healthy adults for the purpose to generate data for establishing rate of drug delivery of Transderm Scop® TDDS (transdermal drug delivery system) in…
- Trial name
- NCT03029650
- Testing
- Transderm Scop®, Intravenous scopolamine hydrobromide
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Peer Review, Research
Fentanyl Patch Pharmacokinetics in Healthy Adults
The study to be performed will utilize already FDA-approved marketed products in healthy adults for the purpose to generate data for establishing rate of drug delivery comparisons between RLD (reference listed drug) Duragesic ®…
- Trial name
- NCT02531971
- Testing
- Intravenous fentanyl citrate, Duragesic®, Mylan generic fentanyl
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Contraception
PK of Depo SubQ Injected in the Upper Arm
A single-arm trial to demonstrate that Depo-SubQ Provera injected in the upper arm is adequate for effective contraception
- Trial name
- NCT01143207
- Testing
- Medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- FHI 360
Healthy
Pharmacokinetics of Lidocaine in Healthy Adults
The study to be performed will utilize already FDA-approved marketed products in healthy adults for the purpose to generate data for establishing rate of drug delivery of Lidoderm® topical patch (manufactured by Endo…
- Trial name
- NCT03310970
- Testing
- Lidocaine 5% patch, Lidocaine hydrochloride, Lidoderm 5% patch
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Nicole K Brogden
Opioid Use, Opioid-Related Disorders
Comparing State Payer Strategies to Prevent Unsafe Opioid Prescribing
This study examines the comparative effectiveness of opioid review programs in reducing unsafe opioid prescribing in two states: prospective prior authorization (PA) with hard stops in Washington and retrospective review (RR)…
- Trial name
- NCT03932799
- Testing
- Prospective prior authorization (PA) with hard stops in Washington, Retrospective review (RR) with prescriber notification in Ohio
- Where
- 2 sites in United States
- Volunteers
- 5,411 people
- Sponsor
- University of Washington
Hospices, Poly Pharmacy
Standardized Patient-Centered Medication Review in Home Hospice
This is a pilot cluster randomized trial that tests the effect of a novel intervention that trains hospice staff to 1. regularly review, simplify, and align patients' prescribed medications with their goals of care as their…
- Conditions
- Hospices, Poly Pharmacy, Deprescriptions, Caregivers
- Trial name
- SPECTORx (NCT03972163)
- Testing
- NIA Medication Management - Active Comparator, STOPPFrail (Screening Tool of Older Persons Prescriptions), "Discontinuing Medication Appropriately" and "Understanding the Art of Communication about Deprescribing"
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Massachusetts, Worcester
Cross-Sectional Study
The Pharmacist Follows You and Your Medication From Hospital to Your Daily Life and Investigate What This Means to You
Background It is well known that the transfer of a patient from hospital to the general practitioner is related with mistakes in the medication of the patient.
- Trial name
- NCT03079375
- Testing
- basic intervention, extended intervention
- Volunteers
- 1,499 people, healthy volunteers welcome
- Sponsor
- Lene V. Ravn-Nielsen
HIV
Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women
This study will inform international medical guidelines as to whether the Levonorgestrel intrauterine device (LNG IUD), a highly effective long-acting reversible contraceptive method, is safe and acceptable as compared to the…
- Trial name
- NCT01721798
- Testing
- Mirena levonorgestrel IUD, Copper T-380a IUD
- Where
- South Africa
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- FHI 360
Diabetic Macular Edema
Chart Review: Drug Utilization Study in Participants Who Received Ozurdex™ (Dexamethasone Intravitreal Implant) 0.7 mg Injections for Visual Impairment Due to Diabetic Macular Edema (DME)
A retrospective, non-interventional, observational, multi-center, drug utilization study to be conducted in adult participants with visual impairment due to DME treated with Ozurdex implants in Germany and Switzerland from 1…
- Trial name
- NCT03889444
- Testing
- Dexamethasone intravitreal implant
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Allergan
Contraception
Long-Acting Reversible Contraception
In the proposed study, women aged 18-29 seeking oral or injectable contraception will be offered an opportunity to try LARC instead; the FDA-approved options include two types of intrauterine products and one type of subdermal…
- Trial name
- LARC (NCT01299116)
- Testing
- DMPA, oral contraceptives, Implanon®
- Where
- United States
- Volunteers
- 916 people, healthy volunteers welcome
- Sponsor
- FHI 360
Renal Cell Carcinoma
To Examine the Effects of Axitinib Dose Reduction and Interruption for Adverse Event Management Among Patients Receiving Axitinib in for the Treatment of Advanced Renal Cell Carcinoma
To assess how dose reductions or treatment interruptions related to axitinib can be implemented to manage and resolve adverse events occurring among patients with advanced renal cell carcinoma treated with first-line axitinib in…
- Trial name
- NCT04682587
- Testing
- Axitinib, Avelumab, Pembrolizumab
- Where
- United States
- Volunteers
- 481 people
- Sponsor
- Pfizer
Pulmonary Arterial Hypertension
Pilot Chart Review Study Of Sitaxentan Sodium (Thelin) In Patients With Pulmonary Arterial Hypertension (PAH)
The objectives of this study are to develop research methods and corresponding materials for a study of the effectiveness of sitaxentan sodium (Thelin) in "real-world" settings; to pilot test these methods at three study centers…
- Trial name
- NCT01445873
- Testing
- Sitaxentan sodium
- Volunteers
- 36 people
- Sponsor
- Pfizer