Clinical trials: Melasma (Facial Melasma)
Melasma
Split-face Study Comparing the Cosmetic Efficacy and Tolerability of Two Topical Products in Participants With Moderate Facial Melasma
The objective of this study is to evaluate the efficacy and tolerability of Lytera 2.0 versus 4% hydroquinone in the improvement of the appearance of moderate facial melasma.
- Trial name
- NCT02977507
- Testing
- Lytera 2.0, 4% Hydroquinone Topical Cream, SkinMedica Facial Cleanser
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Allergan
Melasma
Tranexamic Acid With Microneedling in Melasma
Topical tranexamic, a hydrophilic molecule, can't pass the lipid barriers of the stratum corneum and it's also not retained in adequate amount in the epidermis to enter the melanocytes, so there's a difficulty in the effective…
- Trial name
- NCT05909072
- Testing
- Hyaluronic acid combined with tranexamic acid microneedling, tranexamic acid microneedling
- Volunteers
- 27 people
- Sponsor
- Zagazig University
Melasma
Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study
The goal of this clinical trial is to learn if Eflornithine hydrochloride cream works to treat melasma in adults, in comparison to Hydroquinone cream. It will also learn about the safety of Eflornithine hydrochloride cream.
- Trial name
- NCT06957834
- Testing
- Eflornithine hydrochloride cream, Hydroquinone cream
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- National Skin Centre
Hyperpigmentation
Efficacy and Tolerability of the Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06253455
- Testing
- tested product
- Where
- China
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Pigmentation, Pigmentation Disorder
Effects of RF Microneedle on Photoaging Skin
Melasma relapse is almost common after discontinuation of conventional treatment. Recent studies have suggested that photoaging dermis is main pathomechanism of melasma emphasizing stromal targeting therapy.
- Trial name
- NCT05710068
- Testing
- RF Microneedle, Combination cream
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Ajou University School of Medicine