Clinical trials: Melatonin
Breast Cancer
Melatonin Postoperative Sleep Study in Breast Cancer Patients
Primary Objective: To evaluate the impact of postoperative exogenous nocturnal melatonin supplementation on the early regulation of the sleep-wake cycle and its clinical impact (subjective improvement of the quality of sleep and…
- Trial name
- NCT00506064
- Testing
- Melatonin, Questionnaire
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Osteo Arthritis Knee
Melatonin Use After Primary Total Joint Arthroplasty
The purpose of this study is to determine the effect of melatonin supplementation on patient sleep quality, length of stay, and opioid consumption following primary, unilateral, elective total hip or knee arthroplasty.
- Trial name
- NCT04795336
- Testing
- Melatonin 5 mg
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- NYU Langone Health
Major Depressive Disorder
Efficacy and Safety Study of a Combination Product [Drug:BCI-024 (Buspirone) and Drug:BCI-049 (Melatonin)] to Treat Major Depressive Disorder (MDD)
The primary objective of this study are to evaluate the synergistic effect of a combination product, consisting of drug BCI-024 (buspirone) and drug BCI-049 (melatonin), in reducing symptoms of depression in patients with Major…
- Trial name
- NCT00705003
- Testing
- BCI-024: over-encapsulated Buspirone tablet 15 mg QD and BCI-049: over-encapsulated Melatonin tablet 3 mg QD, BCI-024 (Buspirone)
- Where
- 9 sites in United States
- Volunteers
- 142 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Preoperative Anxiety
Comparing the Effect of Melatonin, Diazepam, and Placebo on Decreasing the Level of Anxiety Preoperatively
The goal of this clinical trial is to compare the effect of melatonin, diazepam, and placebo on the level of anxiety in patients undergoing surgery.
- Trial name
- NCT06103188
- Testing
- Diazepam, Melatonin
- Where
- Jordan
- Volunteers
- 87 people
- Sponsor
- University of Jordan
Postoperative Pain, Delirium
Study of Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery
Pain, confusion, and breaks in normal sleep cycles have been challenges commonly faced by patients after undergoing joint surgeries.
- Conditions
- Postoperative Pain, Delirium, Confusion, Sleep
- Trial name
- NCT01505465
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hospital for Special Surgery, New York
Non Small Cell Lung Cancer
Adjuvant Melatonin for Prevention of Lung Cancer Recurrence and Mortality
There is evidence to support the use of melatonin, a natural health product, as an additional treatment aid for cancer patients.
- Trial name
- AMPLCaRe (NCT00668707)
- Testing
- melatonin
- Where
- 8 sites in Canada
- Volunteers
- 709 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Sleep Disorder, Blindness
Melatonin Studies of Totally Blind Children
The purpose of this study is to learn more about abnormal body rhythms in blind boys and girls that keep them from falling asleep at bed-time or cause them difficulty staying alert during the day.
- Trial name
- NCT00795236
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Delirium
Prevention of Delirium in Inpatients Utilizing Melatonin
A double blind randomized controlled trial investigating melatonin, 5mg, compared to placebo, given to patients at least 65 years old, admitted to the hospital on a general medical floor, to prevent delirium.
- Trial name
- PODIUM (NCT02654314)
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 277 people
- Sponsor
- Yale University