Clinical trials: Mellitus Diabetes
Diabetes Mellitus, Type 2
A Study of LY3493269 in Participants With Type 2 Diabetes
The main purpose of this study is to determine the side effects related to LY3493269 in participants with type 2 diabetes. Blood tests will be performed to check concentrations of LY3493269 in the bloodstream.
- Trial name
- NCT04515576
- Testing
- LY3493269, Dulaglutide
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes Mellitus
A Long-term Safety Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes
The purpose of this study is to determine the long-term safety of the study drug tirzepatide in combination with oral antihyperglycemic medications in participants with type 2 diabetes.
- Trial name
- NCT03861039
- Testing
- Tirzepatide, Oral antihyperglycemic medication (OAM)
- Where
- 34 sites in Japan
- Volunteers
- 443 people
- Sponsor
- Eli Lilly and Company
Diabetes, Hypertension
Quality IQ Patient Simulation Physician Practice Measurement and Engagement
This study will test the quality of physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and feedback.
- Conditions
- Diabetes, Hypertension, Depression, Osteoarthritis
- Trial name
- Q-IQ (NCT03800901)
- Testing
- Continuing Medical Education, Quality IQ Patient Simulations
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Diabetic Foot Ulcer
TheraGauze™ Alone and Regranex®Gel 0.01% Plus TheraGauze™ in the Treatment of Wagner Stage I Diabetic Foot Ulcers
Patients will be randomized to receive TheraGauze alone or with Regranex to treat diabetic foot ulcer condition. The purpose of the study is provide the sponsor with pilot information regarding the ability of TheraGauze to…
- Trial name
- NCT00389636
- Testing
- TheraGauze, Regranex
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Solsys Medical LLC
Diabetes Mellitus, Type 2
Study Of AVANDAMET® With Or Without Insulin In Type II Diabetes Mellitus Patients. AVANDAMET® is a Registered Trademark of the GSK Group of Companies.
This study was designed to test the safety and efficacy (how well it works) of AVANDAMET in combination with insulin in improving the control of blood sugar when compared with taking insulin on its own.
- Trial name
- NCT00069836
- Testing
- Rosiglitazone/metformin
- Where
- 93 sites in Austria, France and 3 more
- Volunteers
- 272 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus
Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Oral Doses of JTT-252
The purpose of this study is to evaluate the safety, tolerability, and PK of single oral doses of JTT-252 and the effect of food on the PK of JTT-252 in healthy subjects, and to evaluate the safety, tolerability, PK and PD of…
- Trial name
- NCT02120976
- Testing
- JTT-252
- Where
- 2 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Shionogi Inc.
T2DM (Type 2 Diabetes Mellitus)
The Drug-drug Interaction Study of AJU-A51R1 and AJU-A51R2
To evaluate a pharmacokinetic drug interaction between AJU-A51R1 and AJU-A51R2 in healthy male volunteers.
- Trial name
- NCT04970940
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Diabetes Mellitus, Type 2
A Trial to Investigate the Efficacy and Safety of NW Low-Glu® in Patients With Type II Diabetes Mellitus
The goal of this clinical trial is to investigate efficacy and safety of an herbal medicinal product of (NW Low-Glu®) in patients with Type 2 Diabetes Mellitus (T2DM).
- Trial name
- NCT06140485
- Testing
- NW Low-Glu®, Metformin
- Volunteers
- 400 people
- Sponsor
- Natural Wellness Egypt
Obesity, Overweight
A Study of LY3549492 in Adults With Obesity or Overweight With Type 2 Diabetes
The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to evaluate the effects of treatment with LY3549492 compared to placebo in adult participants with obesity or who are overweight…
- Conditions
- Obesity, Overweight, Type 2 Diabetes
- Trial name
- NCT07030868
- Testing
- LY3549492
- Where
- 42 sites in United States, Argentina
- Volunteers
- 1 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Type 2
Acute Study of Effect of Ultrasound Vagus Nerve Stimulation on Glycemia
This is an early feasibility study to evaluate the proof of concept of modulation of glycemia by non-invasive ultrasound vagus nerve stimulation.
- Trial name
- NCT04094649
- Testing
- Ultrasound Vagus Nerve Stimulation (DECIMA)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Aucta Technologies, Inc.
Diabetic Neuropathies, Diabetes Mellitus, Insulin-Dependent
Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes
The purpose of this protocol is to determine if an investigational drug known as LY333531 is effective in treating nerve malfunction in diabetes.
- Conditions
- Diabetic Neuropathies, Diabetes Mellitus, Insulin-Dependent, Diabetes Mellitus, Non-Insulin-Dependent
- Trial name
- NCT00044408
- Testing
- Ruboxistaurin mesylate
- Where
- 35 sites in United States, Canada and 6 more
- Volunteers
- 200 people
- Sponsor
- Chromaderm, Inc.
Type 1 Diabetes, Type 2 Diabetes
Patient Transitioning From Exubera® Inhalation Powder to Technosphere® Insulin Inhalation Powder
The purpose of this study is to allow patients with specific needs for inhaled insulin to continue with inhaled insulin therapy using Technosphere Insulin after Exubera was withdrawn from the market.
- Trial name
- NCT01798914
- Testing
- Technosphere Insulin Inhalation Powder
- Where
- 14 sites in United States
- Sponsor
- Mannkind Corporation
Diabetes, Diabetes Mellitus, Type 2
Comparison of Subject-driven Titration of Biphasic Insulin Aspart (BIAsp) 30 Twice Daily Versus Investigator-driven Titration of BIAsp 30 Twice Daily Both in Combination With Oral Antidiabetic Drugs in Subjects With Type 2 Diabetes
This trial is conducted in Asia. The aim of this trial is to compare BIAsp 30 twice daily individually adjusted by the subject versus BIAsp 30 twice daily individually adjusted by the investigator both combined with oral…
- Trial name
- NCT01618214
- Testing
- biphasic insulin aspart 30
- Where
- 22 sites in China
- Volunteers
- 344 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus
Abbott Sensor Based Glucose Monitoring System Paediatric Study
To evaluate the point accuracy of the Abbott Sensor Based Glucose Monitoring System when used at home by children with diabetes.
- Trial name
- BEAGLE (NCT02388815)
- Testing
- FreeStyle Libre Flash Glucose Monitoring System
- Where
- 9 sites in United Kingdom
- Volunteers
- 89 people
- Sponsor
- Abbott Diabetes Care
Obesity, Type 2 Diabetes
MagDI Canada Study
The objective of the MagDI Canada study is to evaluate the performance and safety of the MagDI System in eligible participants who are indicated for a duodeno-ileal (small bowel) side-to-side anastomosis procedure for partial…
- Trial name
- NCT06467955
- Testing
- Magnet System, DI Biofragmentable
- Where
- 3 sites in Canada
- Volunteers
- 60 people
- Sponsor
- GT Metabolic Solutions, Inc.
Diabetes, Diabetes Mellitus, Type 1
A Trial Investigating the Concentration in the Blood of NN1250 in Children, Adolescents and Adults With Type 1 Diabetes
This trial was conducted in Europe. The aim of this clinical trial was to look into the concentration of NN1250 (insulin degludec/insulin 454) in the blood after one injection of NN1250 in children, adolescents and adults with…
- Trial name
- NCT01030926
- Testing
- insulin degludec, insulin glargine
- Where
- Germany
- Volunteers
- 39 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose
The purpose of this study is to measure the effect of LY2189265 to increase insulin levels in response to glucose intake.
- Trial name
- NCT01300260
- Testing
- LY2189265, Insulin, Glucose
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Obesity, Overweight
A Study to Evaluate the Effects of Enicepatide in Participants With Obesity or Overweight, With or Without Type 2 Diabetes
The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA) being developed for chronic weight…
- Conditions
- Obesity, Overweight, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- NCT07670416
- Testing
- Enicepatide
- Where
- 21 sites in China
- Volunteers
- 300 people
- Sponsor
- Hoffmann-La Roche
Bacterial Infections, Diabetic Foot
Study Evaluating the Safety and Efficacy of a Once-daily Dose of Tigecycline vs Ertapenem in Diabetic Foot Infections (DFI) With a Substudy in Patients With Diabetic Foot Infections Complicated by Osteomyelitis.
The purpose of this study was to look at the safety and effectiveness of a once-daily dose of tigecycline compared to ertapenem for the treatment of diabetic foot infections. The co-primary efficacy endpoints were not met.
- Conditions
- Bacterial Infections, Diabetic Foot, Osteomyelitis
- Trial name
- NCT00366249
- Testing
- Tigecycline, Ertapenem
- Where
- 211 sites in United States, Argentina and 37 more
- Volunteers
- 1,061 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Diabetes
User Performance Evaluation for DARIO™ BGMS
The study aims to evaluate the accuracy of the blood glucose level results obtained from fingertip using the Dario Blood Glucose Monitoring System (BGMS) compared to Yellow Springs Instrument (YSI) as well as to evaluate the…
- Trial name
- NCT02357043
- Testing
- Dario Blood Glucose Monitoring System, YSI
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- LabStyle Innovations Ltd.
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