Clinical trials: Membranous
Macular Holes
PEELED INTERNAL LIMITING MEMBRANE REPOSITION
Macular hiatus (MH) refers to a tissue defect in the photoreceptor cell layer of the inner boundary membrane of the optic disc in the macular region.
- Trial name
- NCT06359548
- Testing
- Peeled ILM Reposition, ILM Peeling
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Patients in Septic Shock
The Effects of a Polyethyleneimine-coated Membrane (oXiris™) for Hemofiltration Versus Polymyxin B- Immobilized Fibre Column (Toraymyxin™) for Hemoperfusion on Endotoxin Activity and Inflammatory Conditions in Septic Shock- A Randomized Controlled Pilot Study (ENDoX-study)
Septic shock has a high mortality risk despite the availability of various treatments. Endotoxin, that is present in the cell walls of gram-negative bacteria, is a potent trigger of innate immunity.
- Trial name
- NCT01948778
- Testing
- oXiris™ filter, Toraymyxin Filter, Standard of Care
- Where
- Switzerland
- Volunteers
- 38 people
- Sponsor
- University of Zurich
ARDS, Human, Extracorporeal Membrane Oxygenation Complication
Effects of Induced Moderate Hypothermia on ARDS Patients Under Venovenous ExtraCorporeal Membrane Oxygenation
Acute respiratory distress syndrome (ARDS) is a lesional pulmonary edema that occurs as a result of direct or indirect lung injury.
- Conditions
- ARDS, Human, Extracorporeal Membrane Oxygenation Complication, Hypothermia
- Trial name
- HypoLungECMO (NCT05306392)
- Testing
- Moderate Hypothermia, Normothermia
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
Periapical Periodontitis
Endodontic Microsurgery With the Use of L-PRF and an Occlusive Membrane: a Randomized Controlled Clinical Trial
This study evaluates the effect of leucocyte and platelet rich fibrin (L-PRF) during endodontic microsurgery (EMS) on patient's post-operative comfort and periapical bone healing.
- Trial name
- NCT02528240
- Testing
- EMS, + occlusive membrane, conebeam CT
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Anesthesia of Mucous Membrane
Comparison of Topical and Nebulized Anesthesia in Patients Undergoing Esophago-Gastro-Duodenoscopy
This study compares the effect of nebulized lidocaine and lidocaine spray in patients undergoing esophago-gastro-duodenoscopy. The investigators evaluate the success rate of the procedure between two methods.
- Trial name
- NCT02317770
- Testing
- Lidocaine Spray, Nebulized Lidocaine
- Where
- Thailand
- Volunteers
- 110 people
- Sponsor
- Mahidol University
Glomerulonephritis
Impact of Dapagliflozin for the Regulation of Immunological Activity in Membranous Nephropathy
WHY IS THIS RESEARCH BEING CONDUCTED? Membranous glomerulonephritis (MN) is an autoimmune disease that affects the kidneys through autoantibodies, meaning that antibodies produced by your body attack your own kidney cells.
- Trial name
- FORXIGEM (NCT07096986)
- Testing
- Forxiga
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Preterm Birth, Preterm Labor
To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis
Implementation of prediction models of risk of spontaneous delivery within 7 days or of intra-amniotic infection in women with preterm labor and intact membranes
- Conditions
- Preterm Birth, Preterm Labor, Intra-amniotic Infection, Amniocentesis Affecting Fetus or Newborn
- Trial name
- OPTIM-PTL (NCT04831086)
- Testing
- Steroid Drug, Tocolytic Agents
- Where
- Spain
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Gingival Recession
Evaluating Coronally Advanced Flap With Platelet-rich Fibrin Membrane and Chorion Membrane for Gingival Recession
The present study was a double-blind, randomised, controlled clinical trial with a parallel design, comparing the coronally advanced flap (CAF) with platelet-rich fibrin (PRF) and chorion membrane (CM) for the treatment of…
- Trial name
- NCT07308405
- Testing
- Coronally advanced flap (CAF) with platelet-rich fibrin (PRF), A similar surgical procedure was followed for the recipient bed preparation similar to that for the PRF membrane. A chorion membrane (Tissue bank, Tata Memorial Hospital, Mumbai, Maharashtra, India) o
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of Dental Sciences, Bareilly, Uttar Pradesh, India
Cardiogenic Shock
Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)
Extracorporeal membrane oxygenation (ECMO) is of great value in supporting patients with cardiac shock. More than 80% ECMO patients will develop renal catastrophe that continuous renal replacement therapy (CRRT) is required.
- Trial name
- ELITE (NCT03549923)
- Testing
- Simultaneous CRRT, Conventional-indication CRRT, Esmolol
- Where
- China
- Volunteers
- 131 people
- Sponsor
- Beijing Anzhen Hospital
Bone Resorption
Guided Bone Regeneration Using Fixed vs Non-Fixed Resorbable Collagen Membranes
The aim of this clinical trial is to compare the horizontal bone gain when grafting a bone substitute with non fixed resorbable collagen membranes (control group), versus fixed resorbable collagen membranes (test group) in…
- Trial name
- NCT06334159
- Testing
- Horizontal GBR with the use of non-resorbable pins for the stabilization of the collagen membrane, Horizontal GBR without the use of non-resorbable pins for the stabilization of the collagen membrane
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Tooth Extraction, Tooth Replacement
Comparison of Two Collagen Membranes for Bone Augmentation Around Dental Implants Restored with Monolithic Zirconia Single Crowns
The goal of this randomized controlled clinical trial is to compare the use of two covering collagen membranes in a bone augmentation procedure around single implants and to assess three different veneering approaches on crowns…
- Trial name
- BioGide-Compr (NCT06724783)
- Testing
- Collagen membrane
- Where
- Switzerland
- Volunteers
- 68 people
- Sponsor
- Dr. med. dent. Malin Strasding
Macular Diseases
Characteristics and Limitations of Intraoperative OCT Supported Membrane Peeling in Macular Diseases
During the last decade optical coherence tomography (OCT) extended the possibilities for in vivo macula diagnostic and was increasingly used for pre- and post-operative imaging of retinal diseases.
- Trial name
- NCT02683694
- Testing
- iOCT
- Where
- Austria
- Volunteers
- 81 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Respiratory and Circulation Failure
The Effect of CQI on the Outcome of Patients Supported With ECMO
This was a prospective observational study in comparison with a retrospective control group(Jan 2015 to Jun 2019). Two ICUs in China were included.
- Trial name
- NCT05024786
- Testing
- continuous quality improvements
- Where
- China
- Volunteers
- 163 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Pregnancy Related, Remote Monitoring
Feasibility of Remote eCTG Monitoring Home@Hospital in Complicated Pregnancies
The objective of this single center, interventional cohort study is to evaluate the feasibility of remote electrophysiological cardiotocography (eCTG) monitoring in complicated pregnancies in a home@hospital setting.
- Conditions
- Pregnancy Related, Remote Monitoring, Feasibility
- Trial name
- HASTA (NCT06859177)
- Testing
- Remote eCTG
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Immediate Dental Implant in Type 2 Extraction Socket, Vestibular Socket Therapy
Vestibular Socket Therapy Using Magnesium Membrane Versus Cortical Lamina for Immediate Implant Placement in Type II Extraction Sockets
This randomized controlled clinical trial evaluates the effectiveness of bioresorbable magnesium membranes compared to traditional cortical lamina in Vestibular Socket Therapy (VST) for immediate implant placement in Type II…
- Trial name
- VST (NCT07526272)
- Testing
- Immediate implant and VST using cortical lamina., Immediate implant and VST using Magnesium membrane.
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mohamed Adel Alfeky
Extracorporeal Membrane Oxygenation
The Consistency of Cardiac Output Measurements by Different Methods in VA-ECMO Patients
Objective： 1. To evaluate the consistency of cardiac output measured by different hemodynamic monitoring methods in patients with VA-ECMO 2.
- Trial name
- NCT04102072
- Testing
- Trendelenburg Maneuver, dobutamine stress test
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Membranous Nephropathy
Combination of Rituximab and Cyclosporine in the Treatment of Primary Membranous Nephropathy
High-grade proteinuria is one of the key determinants of adverse renal prognosis in patients with primary membranous nephropathy (PMN).The main purpose of this study is to determine whether Rituximab combined with Cyclosporine is…
- Trial name
- NCT07861204
- Testing
- Rituximab combined with cyclosporine, rituximab
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Peking University First Hospital
Vitrectomy, Epiretinal Membrane
Performance Comparison of the 25 Gauge 20,000cpm HYPERVIT Dual Blade vs. 10,000cpm ULTRAVIT Vitrectomy Cutter
This prospective randomised controlled trial will be conducted to investigate that increasing the vitrectomy cutting rate from 10,000 cut/min to 20,000 cut/min will result more efficiency and shorter core vitrectomy time, and it…
- Conditions
- Vitrectomy, Epiretinal Membrane, Macular Hole, Vitreous Hemorrhage
- Trial name
- NCT05710458
- Testing
- 25 gauge 20,000 cpm Hypervit Dual Blade, 25 gauge 10,000 cpm Ultravit Vitrectomy Cutter
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- The University of Hong Kong
PROM, Preterm (Pregnancy)
Outcome of Conservative Management in Cases of Pre Mature Rupture of Membranes (PROM) Between 20 and 28 Weeks of Pregnancy in Sohag City Hospitals
Prospective observational study
- Trial name
- NCT06271863
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Sepsis, Acute Renal Failure
Super High-Flux - High Volume Dialysis in Sepsis-Induced Acute Renal Failure
Patients within the intensive care unit who have severe infections causing shock and kidney failure have almost a 60% risk of dying despite antibiotic therapy, surgical drainage of the site of infection and intensive care support…
- Trial name
- NCT00333593
- Testing
- Large pore dialyser, Standard dialyser
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Austin Health
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