Clinical trials: Membranous
Atrial Fibrillation
Safety and Efficacy Study of Amniotic Membrane Patch to Treat Postoperative Atrial Fibrillation
The purpose of this study is to to evaluate the rate of new onset postoperative atrial fibrillation in subjects receiving the amniotic membrane patch placed on the epicardial surface as compared to subjects who did not undergo…
- Trial name
- NCT02193321
- Testing
- Amniotic Membrane Patch
- Where
- United States
- Sponsor
- University of Arizona
Pharmacokinetics, Amoxicillin-clavulanate
Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO)
Pharmacokinetics of antibiotics in critically ill neonates, infants and children on extracorporeal membrane oxygenation (ECMO).
- Conditions
- Pharmacokinetics, Amoxicillin-clavulanate, Piperacillin-tazobactam, Meropenem
- Trial name
- PADECMO (NCT06426836)
- Testing
- Amoxicillin-clavulanate, Piperacillin-tazobactam, Meropenem
- Where
- 3 sites in Belgium
- Volunteers
- 300 people
- Sponsor
- University Hospital, Ghent
Cataract and IOL Surgery, Epi-retinal Membrane
Outcomes of Combined Cataract Surgery With Retinal Surgery for Visually Significant Epiretinal Membrane With Vivity Versus Monofocal Intraocular Lens
To investigate the patient Quality of Life and satisfaction outcomes of combined cataract surgery with retinal surgery for visually significant epiretinal membrane in patients receiving Vivity IOL versus standard monofocal…
- Trial name
- NCT07070492
- Testing
- cataract surgery, retinal surgery
- Volunteers
- 36 people
- Sponsor
- Debbie Kuo, MD
Lupus Nephritis, Lupus Erythematosus, Systemic
Tacrolimus for the Treatment of Systemic Lupus Erythematosus With Membranous Nephritis
The investigators study the efficacy and safety of tacrolimus in the treatment of membranous nephritis secondary to systemic lupus erythematosus.
- Trial name
- NCT00125307
- Testing
- tacrolimus
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Severe Cardiac Insufficiency
Evaluation of Antithrombin Deficiency in Patients of Intensive Care Unit Placed on Extracorporeal Membrane Oxygenation
Prospective, monocentric, non-interventional study in patients placed on extracorporeal membrane oxygenation (ECMO)
- Trial name
- ATECMO (NCT04133844)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Neovascular Age-related Macular Degeneration
Neovascular Age-related Macular Degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness in non-Hispanic white Americans. Neovascular AMD is an advanced form of macular degeneration that historically has accounted for the majority of vision loss…
- Trial name
- NVAMD (NCT01712035)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Oregon Health and Science University
Premature Rupture of Membrane
Fetal and Maternal Outcome in Preterm Premature Rupture of Membranes (PPROM)
The aim of this study is to compare fetal and maternal outcome in cases of PPROM before 34 weeks versus after 34 weeks.
- Trial name
- NCT03491826
- Testing
- rupture of membrane
- Where
- Egypt
- Volunteers
- 1,011 people
- Sponsor
- sarah mohamed hassan
Epiretinal Membrane
Instrument Tissue Interaction at the Grasp Site During Membrane Peeling of Epiretinal Membranes
Epiretinal membranes are a disease of the retinal surface, that may affect visual acuity and cause metamorphopsia. Using vitrectomy with membrane peeling, postoperative improvement of visual acuity and metamorphopsia may be…
- Trial name
- NCT06459284
- Testing
- retrospective data analysis
- Where
- Austria
- Volunteers
- 55 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
End Stage Renal Disease
Efficacy of Uremic Toxins Clearance With Expanded Hemodialysis
The aim of this study is to quantify the B2-microglobulin reduction rate based on the type of extracorporeal therapy (ET) used: HDx (expanded hemodialysis), HDc (high-flux conventional hemodialysis), or HDF (hemodiafiltration).
- Trial name
- NCT04786535
- Testing
- Expanded Hemodialysis, High-flux Conventional Hemodialysis, Hemodiafiltration
- Where
- Mexico
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Antiphospholipid Syndrome
Evaluation of Cell Membrane Expression of Annexin A2 on Monocytes by Flow Cytometry in Primary Antiphospholipid Syndrome
Annexin A2 (ANXA2), an endothelial cell receptor for plasminogen and tissue plasminogen activator, plays a pivotal role in regulation of fibrinolysis in vitro and in vivo and has been identified as a new autoantigen in…
- Trial name
- MONOCYTAN (NCT06373926)
- Testing
- blood withdrawal
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Major Depressive Disorder
A Study of LY03005 vs Pristiq
The objective of this study is to evaluate relative bioavailability between 80 mg LY03005 oral tablets and 50 mg Pristiq® oral tablets after a single dose of each drug in a cross-over 2-period design under fasting condition in…
- Trial name
- NCT03733574
- Testing
- LY03005, Pristiq
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Refractory Glaucoma
Ahmed Glaucoma Valve Alone, With Amniotic Membrane or With Mitomycin C (MMC) for Treatment of Refractory Glaucoma
This randomized, controlled trial (RCT) compares the efficacy and safety of Ahmed Glaucoma Valve (AGV) implantation alone, with 3 minutes MMC application or with a single layer coverage of amniotic membrane.
- Trial name
- NCT00893490
- Testing
- Ahmed Glaucoma Valve (AGV), Mitomycin C (MMC), amniotic membrane coverage
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Prostate Cancer Diagnosis
PSMA PET Scan and mpMRI for Prostate Cancer Detection
Prospective, randomized, phase 2 clinical trial to determine if PSMA PET imaging plus mpMRI improves detection of clinically significant prostate cancer as compared to mpMRI alone.
- Trial name
- NCT05820724
- Testing
- PSMA PET scan, No PSMA PET, 18F- DCFPyl Injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Menstrual Cycle
Menstrual Cycle and Platelet-rich Fibrin
The goal of this clinical trial is to test effect of menstrual cycle (MC) on growth factors of platelet rich fibrin (PRF) in health condition.
- Trial name
- NCT06060574
- Testing
- Platelet rich fibrin device
- Volunteers
- 36 people
- Sponsor
- Necmettin Erbakan University
Corneal Ulcers, Corneal Melting
Safety Study of a Sutureless Amniotic Membran Transplantation to Treat Ocular Surface Disorders (Expanded Access)
The investigators aimed at developing a technique to apply amniotic membrane to a diseased ocular surface without surgical intervention (sutureless amniotic membrane transplantation).
- Trial name
- AmnioClip (NCT02168790)
- Testing
- Amniotic membrane ring
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Klinikum Chemnitz gGmbH
Chorioamnionitis
Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis
Chorioamnionitis is an infection of the placenta and amniotic membranes (bag of waters) surrounding the baby inside of a pregnant woman prior to delivery.
- Trial name
- NCT00879190
- Testing
- Unasyn, Ampicillin/gentamicin
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Stanford University
Age Related Macular Degeneration
Wet AMD Recurrence Rate in Patients Stable on Three Month Ranibizumab Dosing
The current norm in clinical practice for the treatment of choroidal neovascular membranes (CNVM) secondary to Age-related Macular Degeneration(AMD) involves monthly injections of Ranibizumab until the disease is stabilized.
- Trial name
- NCT01453920
- Testing
- Ranibizumab
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Epiretinal Membrane, Macular Oedema
Evaluation of Retinal Parameters in Patients With Epiretinal Membrane After Vitrectomy
The goal of this interventional study is to assess the dynamics of structural and functional retinal changes in eyes with epiretinal membrane (ERM) after pars plana vitrectomy (PPV).
- Conditions
- Epiretinal Membrane, Macular Oedema, Macular Diseases, Retinal Diseases
- Trial name
- NCT07165626
- Testing
- Subtreshold micropulse laser therapy, Pars plana vitrectomy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Pomeranian Medical University Szczecin
Macular Edema Due to Diabetes Mellitus, Vitreous Hemorrhage
Comparison of Restoration in Vitreous Hemorrhage Patients With DME After or Not Removing Inner Limiting Membrane
This study is conducted to compare the anti-VEGF effect and visual function in vitreous hemorrhage patients with diabetic macular edema after pars plana vitrectomy with inner limiting membrane peeling or not
- Trial name
- NCT05529589
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Retinal Detachment, Surgery
Internal Limiting Membrane Flap in the Management of Retinal Detachment Due to Paracentral Retinal Breaks
To describe the technique and outcomes of using either inverted or free internal limiting membrane flap in the management of retinal detachment due to paracentral retinal breaks.
- Trial name
- NCT03707015
- Volunteers
- 9 people
- Sponsor
- San Ni Chen
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