Clinical trials: Membranous
Cardiogenic Shock, Extracorporeal Membrane Oxygenation Complication
Cangrelor on Top of anticoagUlation in Patients With myocaRdial Infarction-related Cardiogenic Shock/Cardiac Arrest receiVIng VA-ECMO
The SURVIVE trial aims to test whether using an anti-thrombotic regimen involving cangrelor can reduce bleeding risk while maintaining effective antithrombotic effects in patients on VA-ECMO due to cardiogenic shock (CS)/ cardiac…
- Conditions
- Cardiogenic Shock, Extracorporeal Membrane Oxygenation Complication, Platelet Dysfunction
- Trial name
- SURVIVE (NCT06792643)
- Testing
- Cangrelor
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Acute Respiratory Distress Syndrome
Assessment of Cardiac Output in Patients With ARDS Implanted With Venous-venous ECMO.
In patients with severe acute respiratory distress syndrome, extracorporeal membrane oxygenation (ECMO), which also as known as extracorporeal life support, may be used.
- Trial name
- PiCCMO (NCT05164484)
- Testing
- Transpulmonary thermodilution
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bone Formation Around Implant After Crestal Sinus Lifting
Assessment Crestal Maxillary Sinus Membrane Elevation Using Different Implant Heights
This study is aiming to evaluate primary stability and bone gain in trans-crestal osseodencification technique using Regular concaved osteotomes at different height elevations.
- Trial name
- NCT05166434
- Testing
- trans-crestal sinus lifting
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Premature Rupture of Membrane, Unfavorable Cervix
Randomized Control Trial of Intracervical Balloon Placement vs Oxytocin in Women With Term PROM and Unripe Cervices
This study is designed to determine if an intracervical balloon catheter (IBC) is better than oxytocin for induction of labor in the setting of premature rupture of membranes (PROM) or breaking the bag of water prior to onset of…
- Trial name
- NCT03172858
- Testing
- Intracervical balloon catheter, Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Limbal Stem Cell Deficiency (LSCD)
The Improvement of Limbal Stem Cell Deficiency (LSCD) in Unilateral Stem Cell Damage by Amniotic Membrane Extract Eye Drop (AMEED)
Corneal epithelial cells and limbal stem cells (LSC) are located in the limbus basal epithelium that are necessary for repair of corneal.
- Trial name
- NCT02649621
- Testing
- Amniotic Membrane Extract Eye Drop (AMEED)
- Volunteers
- 10 people
- Sponsor
- Royan Institute
Gingival Recession
Placental Membrane for Root Coverage
Aim of the study was to evaluate the clinical efficacy of placental membrane with coronally advanced flap in covering single and multiple Miller's class I and II gingival recession defects.
- Trial name
- NCT03053921
- Testing
- recession coverage, recession coverage and membrane
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Nephrotic Syndrome Due to Idiopathic Membranous Nephropathy, Severe Proteinuria Due to Idiopathic Membranous Nephropathy
A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN and Severe Proteinuria
This study is an exploratory, randomized, double-blind, multicenter, placebo-controlled study with repeated doses of AP1189. The study population will consist of patients with idiopathic membranous nephropathy (iMN) and severe…
- Trial name
- NCT04456816
- Testing
- 100 mg AP1189
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- SynAct Pharma Aps
Labor, Premature
Tocolytics Trial: Intravenous (IV) Magnesium Versus Oral Nifedpine in Fetal Fibronectin (FFN) Postive Population
In women with singleton gestations, to contemporarily assess the efficacy of oral nifedipine versus intravenous magnesium sulfate in the acute management of preterm labor in terms of defined early and late neonatal measures
- Trial name
- NCT00641784
- Testing
- Magnesium, Nifedlipine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- MemorialCare
Tooth-loss
The Use of Platelet-rich Fibrin (PRF) Membranes in Lateral Alveolar Ridge Augmentation When Jaw Bone is Missing Before Dental Implant Installation. A Study Comparing an Autogenous Bone Block Graft Covered Either by a (PRF) Membrane (Test) or Bone Substitute and a Barrier Membrane (Control)
Tooth loss can in many cases be treated with an artificial titanium root (dental implant) and subsequent manufacture of a porcelain crown.
- Trial name
- NCT04350749
- Testing
- PRF is added in the test group.
- Where
- Denmark
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Idiopathic Membranous Nephropathy
Efficacy of Rituximab Combined With Cyclosporine in the Treatment of Idiopathic Membranous Nephropathy
Idiopathic membranous nephropathy (IMN) is one of the common types of primary glomerular diseases and the most common cause of nephrotic syndrome in adults.
- Trial name
- NCT05782933
- Testing
- Rituximab, Modified Ponticelli regimen
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Beijing Friendship Hospital
Periodontal Diseases, Intrabony Defects
A Clinical Trial to Evaluate the Safety and Effectiveness of Resorbable Collagen Membrane - MatrixflexTM
This is a randomized, single blind, parallel-arm, multi-center, non-inferior clinical trial. 174 patients are recruited in total, and they are treated by Guided Tissue Regeneration (GTR).
- Conditions
- Periodontal Diseases, Intrabony Defects, Guided Tissue Regeneration
- Trial name
- NCT04851847
- Testing
- Guided Tissue Regeneration (GTR)
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Collagen Matrix
Chronic Periodontitis
Evaluation of Amnion Chorion Membrane and Demineralized Bone Matrix Putty Allograft in Periodontal Intrabony Defects
A clinical and radiographic evaluation of 2 regenerative techniques, bioresorbable membrane and bone allograft for management of periodontal intrabony defects.
- Trial name
- NCT02679209
- Testing
- Demineralized bone matrix in putty form, Amnion chorion membrane
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diaphragm, Extracorporeal Membrane Oxygenation Complication
Evolution of Diaphragm Thickness Under Veno-arterial ECMO
The main objective is to evaluate the evolution of the thickness of the diaphragm (during the first week of treatment) by VA ECMO in the resuscitation patients.
- Trial name
- ATROPHY-ECMO (NCT04052230)
- Testing
- ultrasound measure
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Prostate Cancer
68Ga-RM2 Compared to 68Ga-PSMA-617 PET/CT for Intermediate Risk Prostate Cancer Imaging
Patients with primary intermediate risk prostate cancer for whom radical prostatectomy is indicated, will be invited to participate to the present study.
- Trial name
- PROSTATEP (NCT03606837)
- Testing
- 68Ga-PSMA-617 PET/CT, 68Ga-RM2 PET/CT
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Bordeaux
Adenoid Cystic Carcinoma
The Evaluation of the Effectiveness, Safety and Tolerability of Treatment, Using a PSMA-Lu177, in Patients with ACC- an Open, Non-commercial Clinical Trial
Non-commercial phase 2 clinical trial to evaluate the effectiveness, safety and tolerability of treatment using prostate-specific membrane antigen (PSMA) labeled with 177Lutetium in patients with recurrence and/or metastases in…
- Trial name
- LuRM_ACC/2023 (NCT06199453)
- Testing
- Lutetium (177Lu) vipivotide tetraxetan
- Where
- Poland
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Cardiopulmonary Arrest, Fungal Infection
Pharmacokinetics/Pharmacodynamics (PK/PD) of Fluconazole in Children on Extracorporeal Membrane Oxygenation (ECMO)
Extracorporeal membrane oxygenation (ECMO) is a form of heart-lung bypass used to support children who suffer heart or lung failure until whatever illness caused that failure can be treated and reversed.
- Trial name
- NCT01169402
- Testing
- Fluconazole
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Michael Cohen-Wolkowiez
Osteoarthritis, Knee
Efficacy and Safety of NEM® Brand Eggshell Membrane in Patients With Grade 2/3 Knee Osteoarthritis
This study was designed to evaluate the efficacy and safety of NEM® brand eggshell membrane in patients with grades 2 and 3 knee osteoarthritis (OA) having significant joint pain and stiffness, in a large, multi-center clinical…
- Trial name
- NCT02291757
- Testing
- NEM brand eggshell membrane
- Where
- 8 sites in Turkey (Türkiye)
- Volunteers
- 166 people
- Sponsor
- Generica Pharmaceuticals
Tooth Loss, Recession, Gingival
Use of Leucocyte- and Platelet-rich Fibrin Membranes in Single Implant
The objective of this randomized controlled clinical trial is to evaluate the increase of soft tissue thickness around single implants installed in maxillary esthetic area with the use of Leucocyte-Platelet rich Fibrin (L-PRF)…
- Trial name
- NCT03660566
- Testing
- Test - Implant with L-PRF, Control - Implant without L-PRF
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Mechanical Circulatory Support
Cerebral Oximetry, Pulmonary Artery Catheter Parameters and ECMO Flow in Patients Supported With Veno-arterial ECMO
for patients connected to VA ECMO due to cardiogenic shock, monitoring: 1. Cerebral Oximetry 2. ECMO Parameters ECMO blood flow (L/min) every 12 hours. Sweep gas flow Cannulation configuration 3.
- Trial name
- ECMO (NCT07526181)
- Volunteers
- 30 people
- Sponsor
- Assiut University
Extracorporeal Clotting During Hemodialysis
Effect of Nephral 400 ST Dialysis Membrane on Coagulation in Hemodialysis
The purpose of this study is to investigate whether the dialysis filter AN69ST (Nephral 400 ST Dialysis Membrane) induces less clotting during hemodialysis than a conventional polysulphone filter.
- Trial name
- NCT00594607
- Testing
- AN69ST dialysis membrane, Fx8 (Fresenius)
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Ullevaal University Hospital
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