Clinical trials: Membranous
ECMO, Training Effectiveness
Virtual Reality Training for ECMO Circuit Checks
Purpose of the Study: This investigation will examine whether a brief session with an immersive virtual-reality headset can prepare critical-care nurses to carry out an eleven-step extracorporeal membrane oxygenation circuit…
- Conditions
- ECMO, Training Effectiveness, Education Nursing, Educational Intervention
- Trial name
- HEALTH-ECMO-VR (NCT07138599)
- Testing
- Virtual Reality ECMO Simulation Training, Instructional Video of Certified Perfusionists on Performing a Circuit Check
- Where
- 2 sites in Netherlands
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
HIV Infections
Safety and Tolerability of the Vaginal Gel PRO 2000/5
The purpose of this study is to determine whether the vaginal gel PRO 2000/5 causes irritation when used daily. Studies have shown PRO 2000/5 is safe and well tolerated as a vaginal gel in healthy women who are not sexually…
- Trial name
- NCT00006207
- Testing
- PRO 2000
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cardiac Arrest, Myocardial Infarction
Monitoring Antiplatelet Drugs in Cardiac Arrest Patients
Dual Antiplatelet Therapy (DAPT) with acetylsalicylic acid (ASA) and oral P2Y12 inhibitor (Clopidogrel, Ticagrelor or Prasugrel) is recommended in STEMI or NSTEMI patients undergoing primary Percutaneous Coronary Intervention…
- Conditions
- Cardiac Arrest, Myocardial Infarction, Extracorporeal Membrane Oxygenation, Platelet Dysfunction
- Trial name
- PLT-ECMO (NCT05730114)
- Testing
- Antiplatelet Drug
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Milano Bicocca
Newborn Respiratory Distress, Preterm Infant
Short Term Effects of Synchronized vs. Non-synchronized NIPPV in Preterm Infants.
Comparing the cardio-respiratory adaptation and differences to non invasive ventilation techniques, nasal intermittent positive pressure ventilation (NIPPV) non synchronized vs synchronized (SNIPPV) in preterm newborns…
- Trial name
- SyncNIV (NCT03289936)
- Testing
- NIPPV, SNIPPV
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Prostate Cancer Metastatic
68Ga-PSMA-R2 in Patients With Biochemical Relapse (BR) and Metastatic Prostate Cancer (mPCa)
This was an open-label, multicenter, single dose, Phase I/II study to evaluate the safety and tolerability of a single administration of 3 mega Becquerel (MBq)/kg, but not less than 150 MBq and not more than 250 MBq, of…
- Trial name
- PROfind (NCT03490032)
- Testing
- [68Ga]-PSMA-R2
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Advanced Accelerator Applications
Idiopathic Membranous Nephropathy
Obinutuzumab in the Management of Idiopathic Membranous Nephropathy
To observe the efficacy and safety of obinutuzumab in Chinese population with idiopathic membranous nephropathy and guide clinical management.
- Trial name
- NCT05845762
- Testing
- Obinutuzumab Injection
- Volunteers
- 30 people
- Sponsor
- Qianfoshan Hospital
Fibromyalgia
Membrane Lipid Replacement in Fibromyalgia
The purpose of this study is to determine the clinical effectiveness of an all-natural, patented wafer with active ingredients that are FDA approved as Generally Recognized as Safe (GRAS) Reference: US Federal Drug Administration…
- Trial name
- NCT03288389
- Testing
- NTFactor Lipids®
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Institute for Molecular Medicine
Diabetic Macular Edema, Vision Disorders
Effect of Intraoperative Dexamethasone Implant in Taut Posterior Hyaloid Removal in Diabetic Macular Edema
This study is undertaken to determine effect of sustained release dexamethasone implant,Ozurdex in improving outcome of taut posterior hyaloid removal in patients with diabetic macular edema Diabetic macular edema constitute…
- Trial name
- NCT01698788
- Testing
- Dexamethasone Drug delivery system (Ozurdex)
- Where
- India
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Prostate Cancer (Adenocarcinoma), Adenocarcinoma of the Prostate
RYZ711 Diagnostic Platform Study
This is a Phase 1/2 multicenter, multi-cohort imaging study to evaluate the safety, tolerability, and diagnostic performance of RYZ711 positron emission tomography/computed tomography (PET/CT) in men with histologically confirmed…
- Conditions
- Prostate Cancer (Adenocarcinoma), Adenocarcinoma of the Prostate, Metastatic Castration-resistant Prostate Cancer (mCRPC), Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
- Trial name
- NCT07862582
- Testing
- RYZ711, PSMA PET/CT
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- RayzeBio, Inc.
Paroxysmal Nocturnal Hemoglobinuria
A Safety and Immunogenicity Study in Long-term Treatment of Eculizumab (JSC "GENERIUM", Russian Federation)
A safety and immunogenicity study in long-term treatment of Eculizumab (JSC "GENERIUM", Russian Federation) in patients with paroxysmal nocturnal hemoglobinuria, who have been involved earlier in the clinical trials of Eculizumab…
- Trial name
- NAP (NCT04679103)
- Testing
- Eculizumab (JSC GENERIUM, Russia)
- Where
- 9 sites in Russia
- Volunteers
- 50 people
- Sponsor
- AO GENERIUM
Delivery, Obstetric
The Effect of Membrane Sweeping on the Delivery Time and the Need of Induction in Term Pregnancy
Pregnancies that extend beyond 42 weeks of gestation are at an increased risk for poor fetal and maternal outcomes. For decreasing the number of these cases, some labor induction techniques are used.
- Trial name
- NCT03591159
- Testing
- Membran Sweeping
- Where
- Turkey (Türkiye)
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Ankara University
Colorectal Cancer
Cell Membrane Potential Regulates Spatial-Specific Mechanoptosis Resistance and Metastasis in Colorectal Cancer Via Mechanotransduction and the PVR/CD96 Axis
Spatial heterogeneity represents a pivotal driver of therapeutic resistance and metastatic progression in colorectal cancer (CRC).
- Trial name
- NCT07650786
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Ma Tianyi
Preterm Labor (24 GA - 32 GA)
Identification of Spontaneous Delivery Markers
The investigators project aims to identify, in pregnant women, discriminating molecules to allow an early detection of women who will spontaneously deliver prematurely, suitable in routine clinical practice.
- Trial name
- TrophY2 (NCT02225717)
- Testing
- Cervicovaginal swab
- Where
- France
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neurodegeneration With Brain Iron Accumulation (NBIA), Pantothenate Kinase-associated Neurodegeneration (PKAN)
TIRCON International NBIA Registry
TIRCON-reg aims to continue the provision of a global registry and natural history study for NBIA disorders harmonize and cover existing national and single site registries enable participation of countries and single sites that…
- Conditions
- Neurodegeneration With Brain Iron Accumulation (NBIA), Pantothenate Kinase-associated Neurodegeneration (PKAN), Beta-Propeller Protein-Associated Neurodegeneration (BPAN), Mitochondrial Membrane Protein Associated Neurodegeneration (MPAN)
- Trial name
- TIRCON (NCT05522374)
- Where
- 9 sites in Canada, Czechia and 6 more
- Volunteers
- 2,000 people
- Sponsor
- LMU Klinikum
Airway Obstruction
Ultrasonography Versus Palpation for Identification of the Cricothyroid Membrane
After a structured teaching program anaesthetists are educated in identifying the cricothyroid membrane with ultrasonography. Thereafter their ability to do so is compared with their ability to do so with palpation.
- Trial name
- NCT02975791
- Testing
- Marking the cricothyroid membrane after ultrasound, Marking of the cricothyroid membrane after Palpation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Preterm Premature Rupture of Membranes, Fetal Inflammatory Response Syndrome
Multimodal Monitoring of Fetal Risk of Inflammation in Preterm Premature Rupture of Membranes
The purpose of this study is to examine whether the value of vaginal fluid cytokine levels as well as computerized fetal ECG analysis are suitable clinical parameters to detect an imminent intra-amniotic inflammation with a high…
- Conditions
- Preterm Premature Rupture of Membranes, Fetal Inflammatory Response Syndrome, Early Onset Neonatal Sepsis, Infection of Amniotic Cavity
- Trial name
- MuMFI-PPROM (NCT02702297)
- Testing
- single arm
- Where
- 4 sites in Germany
- Volunteers
- 57 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Primary Membranous Nephropathy
Study of YK012 in Primary Membranous Nephropathy
The goal of this clinical trial is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity, and preliminary efficacy of YK012 in participants with primary membranous nephropathy (PMN).
- Trial name
- NCT06982729
- Testing
- YK012
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Excyte Biopharma Ltd
Idiopathic Membranous Nephropathy
Rituximab Combined With Cyclosporine Versus Rituximab Alone in the Treatment of iMN
The primary objective of this study is to determine whether or not cyclosporine (CsA) combined with RTX is more effective than RTX alone in the treatment of idiopathic membranous nephropathy (iMN).
- Trial name
- NCT04743739
- Testing
- Rituximab, cyclosporine
- Where
- 7 sites in China
- Volunteers
- 12 people
- Sponsor
- Peking Union Medical College Hospital
Hallux Rigidus
Amniotic Membrane as an Adjunct Treatment for Hallux Rigidus
The purpose of this study is to determine whether patients undergoing a dorsal cheilectomy procedure with implementation of amniotic membrane tissue results in improved clinical and functional outcomes compared to a standard…
- Trial name
- NCT01825356
- Testing
- Dorsal Cheilectomy without Amniotic Membrane Tissue Implantation, Dorsal Cheilectomy with Amniotic Membrane Tissue Implantation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Vascular Endothelial Growth Factor Overexpression, Membrane Alteration
Perforated Barrier Membranes Maintain Physiologic Gingival Crevicular Fluid Growth Factor Levels
Membrane modifecation: Guided tissue membrane perforations may serve as a more biologic scaffold that could allow for the free passage of biologic mediators from the periosteum and overlying gingival connective tissue into the…
- Trial name
- NCT02168322
- Testing
- collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.