Clinical trials: Membranous
Cesarean Section Complications
RCT Investigating Pre-cesarean Vaginal Wash of Chlorhexidine vs Povidone-iodine for Patient With Ruptured Amniotic Membrane.
The objective of this study is to investigate if the rate of infectious morbidity is decreased with the use of chlorhexidine or povidone-iodine vaginal scrub before cesarean section after ruptured membranes.
- Trial name
- VAP (NCT03925155)
- Testing
- EZ scrub vaginal chlorhexidine 4% solution, 10% provodine-iodine vaginal preparation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Chronic Periodontitis
Clinical, Anti-Inflammatory And Anti-Infective Properties Of Amniotic Membranes Used For Guided Tissue Regeneration
The objective of this study is to evaluate the anti-inflammatory and anti-infective properties of amniotic membrane (AM) when used for guided tissue regeneration (GTR) in periodontal bone defects.
- Trial name
- NCT02033226
- Testing
- Amniotic Membrane, Control group (Hydroxyapatite only)
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Surgery for Cataract, Surgery for and Idiopathic Epiretinal Membrane
Validation of a Prognostic Score for Good Visual Recovery at One Year Following Combined Surgery for Cataract and Idiopathic Epiretinal Membrane
The prevalence of idiopathic epiretinal membranes (ERM) in people over 50 is estimated at 6 to 19%. Even though most cases show very few symptomats, they may induce alterations of the underlying retina and lead to visual…
- Trial name
- PROCATMER (NCT03329976)
- Testing
- measurement of visual acuity
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Glomerulonephritis, Membranous, Nephrotic Syndrome，Idiopathic
Clinical Study of Rituximab for the Treatment for Idiopathic Membranous Nephropathy With Nephrotic Syndrome
To confirm the efficacy and safety of rituximab (genetical recombination) intravenously administered to idiopathic membranous nephropathy with nephrotic syndrome.
- Trial name
- PRIME (NCT05914155)
- Testing
- Rituximab (genetical recombination)
- Where
- 18 sites in Japan
- Volunteers
- 88 people
- Sponsor
- Shoichi Maruyama MD PhD
Myopia, Choroidal Neovascularization
Efficacy and Safety of Intravitreal Bevacizumab in the Treatment of Choroidal Neovascular Membranes Associated to High Myopia
The purpose of this study is to determine the efficacy and safety of intravitreal injections of bevacizumab in High Myopia´s choroidal neovascularization versus the standard treatment of Photodynamic therapy.
- Trial name
- NCT00967850
- Testing
- Intravitreal Injection, Photodynamic Therapy (Visudyne)
- Where
- 7 sites in Spain
- Volunteers
- 56 people
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Renal Failure, End Stage Renal Disease
Safety and Clinical Performance of a Dialyzer With a Modified Polysulfone Membrane
The clinical investigation will be performed to generate clinical data on clearances and removal rates (for ß2-microglobulin, myoglobin, phosphate, creatinine, and urea) as well as biocompatibility of the modified polysulfone…
- Trial name
- eMPORA (NCT03315624)
- Testing
- Dialyzer
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Epiretinal Membrane
Outcomes of Vitrectomy Combined With Subtenon Triamcinolone Injection for the Idiopathic Epiretinal Membrane
This study compares the anatomical and visual outcomes of patients with idiopathic epiretinal membrane(ERM) treated by vitrectomy and membrane peeling with or without subtenon triamcinolone acetonide injection
- Trial name
- NCT01630876
- Testing
- Vitrectomy only group, Combined therapy group
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yeungnam University College of Medicine
Diabetes Mellitus, Type 2, Artery Disease
Arterial Composition and Cardiovascular Outcome in DIabeteS
1. People living with type 2 diabetes are told that they have a significantly higher risk of developing a disease related to the heart or blood vessels.
- Conditions
- Diabetes Mellitus, Type 2, Artery Disease, Protein Deposition
- Trial name
- ACCODIS (NCT04150315)
- Testing
- Proteome analysis
- Where
- Denmark
- Volunteers
- 763 people
- Sponsor
- University of Southern Denmark
Knee Injuries
Large-scale Expansion and Characterization of Mesenchymal Stem Cells for Clinical Application
According to many recent research, mesenchymal stem cells (MSC) isolated from synovial membrane and infrapatellar fat pad have higher ex vivo proliferation capacity, multipotency and ability to undergo chondrogenesis.
- Trial name
- NCT02375568
- Testing
- 103024-F
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- Chin-Hung Chang
Relapsed Prostate Cancer
Prospective Evaluation of 68-Ga-prostate Specific Membrane Antigen (PSMA)-Positron Emission Tomograph (PET) and Early Prostatic Specific Antigen (PSA) Kinetics During Salvage Radiotherapy for Personalizing the Management of Men With Relapse of Prostate Cancer After Radical Prostatectomy
This is an open-label, phase II trial in patients with PSA recurrence after prostatectomy. Patients entering the study will all receive initial 50 Gray (Gy) radiotherapy (25 x 2Gy) to the prostate bed and thereafter be classified…
- Trial name
- PROPER (NCT02699424)
- Testing
- External radiation therapy
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Lund University Hospital
Early Labor
Membrane Sweeping in Early Labor and Delivery Outcomes
Membrane sweeping is a routine procedure in obstetrics in term patients. It has been shown to be effective in decreasing post term gestation and in increasing rate of spontaneous vaginal delivery when used in setting of induction…
- Trial name
- NCT03517696
- Testing
- Membrane sweeping
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Retinal Detachment, Proliferative Vitreoretinopathy
Internal Limiting Membrane Peeling in Retinal Detachment Surgery
Despite advances in surgical techniques over the recent decades, proliferative vitreoretinopathy (PVR) remains the main obstacle to successful rhegmatogenous retinal detachment (RRD) repair, accounting for nearly 75% of all…
- Trial name
- IMPURITY (NCT05538156)
- Testing
- Control group, Intervention group
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Coronary Artery Disease
Short-term Outcomes of Elective High-risk PCI With Extracorporeal Membrane Oxygenation Support: a Single-centre Registry
Background Revascularization of complex coronary artery disease, including multivessel coronary artery disease, left main stenosis, bifurcation stenosis and chronic total occlusions (CTO) can be performed by Percutaneous Coronary…
- Trial name
- NCT05387902
- Testing
- Extracorporeal Membrane Oxygenation
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Robert Jan van Geuns
Alkaline Chemical Burn Of Cornea And Conjunctival Sac, Acid Chemical Burn Of Cornea And Conjunctival Sac
The Improvement of Limbal Epithelial Culture Technique by Using Collagenase to Isolate Limbal Stem Cells
Using collagenase to isolate limbal stem cells and improve the technique of ex vivo expansion of limbal stem cells for the treatment of patients suffering from unilateral limbal stem cell insufficiency based on the concept of…
- Conditions
- Alkaline Chemical Burn Of Cornea And Conjunctival Sac, Acid Chemical Burn Of Cornea And Conjunctival Sac, Benign Mucous Membrane Pemphigoid With Ocular Involvement
- Trial name
- NCT02202642
- Testing
- collagenase
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Pathologic Processes, Diabetes Mellitus
Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs
The purpose of the study is to evaluate the efficacy of multiple human placental membrane products and Standard of Care (SOC) versus SOC alone in the management of nonhealing diabetic foot ulcers (DFUs) and venous leg ulcers…
- Conditions
- Pathologic Processes, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases
- Trial name
- C5CAMP (NCT06674980)
- Testing
- Standard of Care - DFU, AM/Single - DFU, AM/Double - DFU
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- C5 Biomedical
Tympanic Membrane Perforation
Effectiveness of Silver Nitrate Cauterization vs Conservative Management in Tympanic Membrane Perforation Closure
The objective of this study is to evaluate the effectiveness of 50% silver nitrate chemical cauterization compared to conservative management (spontaneous healing) in closing small, dry tympanic membrane perforations.
- Trial name
- NCT07833670
- Testing
- 50% Silver Nitrate Cauterization
- Volunteers
- 56 people
- Sponsor
- Muhammad Ali Javed
Critically Ill Renal Failure Requiring CVVHD and Oseltamivir, Critically Ill Requiring ECMO and Oseltamivir
Pharmacokinetics of Tamiflu® (Oseltamivir) in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO)and or Continuous Venovenous Hemodialysis (CVVHD)
Critically ill patients with flu may receive a drug called oseltamivir. They may also receive medical therapies to support their lung function (extracorporeal membrane oxygenation; ECMO) and kidney function (continuous venovenous…
- Trial name
- NCT01048879
- Testing
- pharmacokinetic blood sampling, pharmacokinetic blood and dialysate sampling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Prostate Cancer
External Beam Therapy With Theranostic Radioligand Therapy for Oligometastatic Prostate Cancer (ProstACT TARGET)
This is a phase II trial to evaluate the therapeutic efficacy of a radiolabelled PSMA-targeting antibody, 177Lu-TLX591, given in combination with external beam radiation therapy (EBRT) in patients with biochemically recurrent…
- Trial name
- NCT05146973
- Testing
- 177Lu-DOTA-TLX591
- Where
- 4 sites in Australia
- Volunteers
- 5 people
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Low Back Pain
Study to Evaluate Ferris PainWrap in the Treatment of Chronic Low Back Pain
The purpose of this study is to see if the Ferris PainWrap is effective in the treatment of chronic low back pain.
- Trial name
- NCT00364065
- Testing
- Ferris PainWrap
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Pain and Rehabilitation Medicine
Catheter-Related Infections
Impact of Prophylactic Antibiotics on Bloodstream Infections After Liberation From Extracorporeal Membrane Oxygenation
The goal of this prospective interventional study is to evaluate the impact of antibiotic prophylaxis on bloodstream infections after liberation of extracorporeal membrane oxygenation therapy.
- Trial name
- IPANEMA-ECMO (NCT05651464)
- Testing
- Vancomycine
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Universität des Saarlandes
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