Clinical trials: Memory Complaint
Healthy Adults With Subjective Memory Complaints
Effects of HX106 on Improvement in Cognitive-Bio-Markers of Memory Function
The objectives of the current study are to evaluate the efficacy and safety of HX106 in healthy adults with subjective memory complaints for improving cognitive and neurobiolgoical markers of memory.
- Trial name
- NCT01956097
- Testing
- HX106 590mg, HX106 1180mg
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Cognitive Impairment, RRSO
IMProving Executive Function Study
This is a double-blind, placebo-controlled, crossover study testing whether Vyvanse (lisdexamfetamine; LDX) improves executive functioning (EF) in 100 postmenopausal women who report onset of EF difficulties after oophorectomy.
- Trial name
- IMPRES (NCT03187353)
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mild Cognitive Impairment (MCI), Subjective Memory Complaint
Validation of a Digital Intervention to Rehabilitate Cognitive Resources
The goal of this clinical trial is to learn if the use of a digital cognitive rehabilitation system named RICORDO, that is flexible and capable of adapting the rehabilitation pathway according to the needs and capacity of the…
- Conditions
- Mild Cognitive Impairment (MCI), Subjective Memory Complaint, Dementia Alzheimer Type
- Trial name
- MI-RICORDO (NCT07064226)
- Testing
- RICORDO, Treatment as Usual (TAU)
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Neurodegenerative Diseases, Mild Cognitive Impairment
Magnetic Resonance Imaging (MRI) of Brain Iron in Neurodegenerative Disease
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis are recognized as a major health concern at the present time.
- Trial name
- NCT00249080
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Subjective Memory Complaint
Lifestyle Remodeling in Subjective Memory Complaint (SMC): Brain Imaging and Blood Biochemistry Study
The specific study aims: 1. To investigate whether the brain function is affected by the past life experiences, such as lifestyle and physiology-related factors in SMC. 2.
- Trial name
- NCT04162990
- Testing
- Lifestyle remodeling Intervention, Does Comparator: regular treatment
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Cognitive Ability, General
Body and Brain Exercise for Older Adults With Memory Complaints
The purpose of this study is to investigate whether an exercise class with a cognitive (or brain) training component was more effective than a usual combined aerobic and resistance exercise class for older adults with cognitive…
- Trial name
- NCT02136368
- Testing
- Multi-modal exercise, Mind-Motor Exercise, Balance and range of motion exercises
- Where
- Canada
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cognitive Impairment
Vascular Alteration and Evolution of Cognitive Impairment
In the cross sectional study "Adelahyde 1" which took place between 2001 and 2005, the investigators data suggest that vascular alterations may play a role in the setting of subjective memory complaints.
- Trial name
- ADELAHYDE2 (NCT01351961)
- Testing
- blood sampling, brain MRI and TEP cerebral, Assessment of cognitive functions
- Where
- France
- Volunteers
- 131 people
- Sponsor
- Central Hospital, Nancy, France
Hypertension
Walking Exercise on Memory, Subjective Cognitive Complaint, and Brain-derived Neurotrophic Factor for Hypertension
The purpose of this study is to determine the effect of 6-month aerobic walking program on memory, subjective cognitive complaints, and brain-derived neurotrophic factor for older hypertensive women.
- Trial name
- NCT04930263
- Testing
- Aerobic exercise, control group
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- National Taiwan University Hospital
Cognitive Decline
ADL+2.0: Intervention for Prevention of Cognitive Decline in Community-dwelling Older Adults
Singapore's rising dementia incidence with an ageing population presents an urgent need for effective interventions that delay or prevent cognitive decline.
- Trial name
- ADL+ 2 (NCT07141160)
- Testing
- Combined: Mobile app + 6WELLS, Remote mobile based app
- Where
- Singapore
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Aging
Everyday Memory Intervention
Evaluates an intervention designed to improve everyday memory function, contrasting people receiving the intervention with a group that receives traditional memory strategy training.
- Trial name
- EMMI (NCT04088136)
- Testing
- Everyday Metacognitive Memory Intervention, Memory Strategy Control Intervention
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Alzheimer's Disease, Cognitive Impairment
Effect of EGb761® on Brain Glucose Metabolism in Three Groups of Elderly Defined by Cognitive Functions
The aim of the study is to evaluate the effect of EGb761®, in comparison to placebo, on cerebral glucose metabolism, in three groups of elderly patients: newly diagnosed mild Alzheimer's disease (AD), memory complaint patients…
- Trial name
- NCT00814346
- Testing
- EGb761®
- Where
- 8 sites in France
- Volunteers
- 49 people
- Sponsor
- Ipsen
Major Depression
Clinical Effectiveness of Choline Alphoscerate for Older Adults With Major Depression and Subjective Memory Complaints
To evaluate the efficacy of choline alphoscerate on improving symptoms related to depression, anxiety, and subjective memory complaints compared to placebo in patients with Major Depressive Disorder(MDD) accompanied with…
- Trial name
- CHOLDEPS (NCT05257902)
- Testing
- choline alphoscerate
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Samsung Medical Center
Fatigue Syndrome, Chronic, Chronic Pain
Subjective Memory Complaints, Objective Memory Performance and Cognitive Training
The aim of this study is to examine if repetitive computerized cognitive training improves working memory in patients who are on sick leave due to complex symptom disorders (chronic pain, chronic fatigue, anxiety, depression and…
- Conditions
- Fatigue Syndrome, Chronic, Chronic Pain, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT02156128
- Testing
- Cogmed working memory training, Control group
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Cerebrovascular Function, Cognition
Oral Ketone Monoester Supplementation and Resting-state Brain Connectivity
People who report subjective memory complaints have a greater risk of developing dementia. Memory issues may be an early warning sign of dysfunctional cerebral glucose metabolism and cerebral blood flow.
- Trial name
- NCT05992571
- Testing
- β-OHB
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Metamemory, Memory Complaints
Relations Between Cognitive Complaints and Cognitive Scores Goals in Cancer: Assessment of Metamemory
This pilot study is, in this new and original approach in cancer pathology, measure and explain the correspondence between perceived cognitive impairment (cognitive complaint) by cancer patients and their cognitive scores goals…
- Conditions
- Metamemory, Memory Complaints, Performance Mnemonic, Cancer
- Trial name
- NCT02212132
- Testing
- behavioral assessments
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Francois Baclesse
Age-Related Memory Disorders
An Examination of Visual Perceptual Training
Perceptual-cognitive training (PCT) is a computerized software game has been shown to improve sport performance in young elite athletes and even to aid in recovery speeds post-concussion.
- Trial name
- NCT03763344
- Testing
- Perceptual Cognitive Training (PCT)
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Victoria
Memory Complaint, Mild Cognitive Impairment
PET Imaging of the Translocator Proteine Ligands (TSPO) With [18 F] DPA-714 Biomarker of NeuroInflammation in Cognitive Decline (NIDECO)
Alzheimer's disease (AD) is the most common cause of dementia in elderly subjects. AD is characterized by brain lesions like extracellular deposits of ß-amyloïd proteins in senile plaques and intracellular neurofibrillary tangles…
- Conditions
- Memory Complaint, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NIDeCo (NCT02062099)
- Testing
- [18F]DPA-714 PET/ [18F]AV-45 PET/neuropsychological assessment
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Tours
Memory Disorders, Age-Related Cognitive Decline
Effect of Vitamin D on Cognitive Decline of Patients With Memory Complaint
As recommended allowance of oral vitamine D are unable to ensure the recommended serum concentration of vitamine D, the purpose of this study is to show that a dose of vitamin D3 higher than the recommended allowance may slow the…
- Trial name
- D-COG (NCT02185222)
- Testing
- Cholecalciferol 100 000 UI
- Where
- 11 sites in France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Tours
COVID-19, Cognitive Impairment
Computerized Training of Attention and Working Memory in Post COVID-19 Patients With Cognitive Complaints
Many post COVID-19 patients suffer from cognitive deficits, even after 1 year after hospitalization. These complaints have a huge impact on psychological well-being and quality of life.
- Conditions
- COVID-19, Cognitive Impairment, Cognition Disorder, Memory Disorders
- Trial name
- CO-TRAINER (NCT05831839)
- Testing
- RehaCom
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Erasmus Medical Center
Planned RRSO
E2 and LDX for the Treatment of Cognitive Complaints After Oophorectomy
This project seeks to address cognitive disturbance, which is a frequent adverse sequelae of riskreducing bilateral salpingo-oophorectomy (RRSO) with or without post-procedure chemotherapy and adjunctive treatments.
- Trial name
- E2LDX (NCT01986764)
- Testing
- Lisdexamfetamine, Estradiol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania