Clinical trials: Memory Functions
Virtual Reality, Anesthesia
HoloLens: an Objective Alternative to the Operator's Memory
Neuraxial anesthesia has traditionally been a 'blind' technique relying on users' feel and skill, both are subjective, lack complete accuracy and influenced by patient's physique variations that are quite challenging, and lead to…
- Conditions
- Virtual Reality, Anesthesia, Epidural
- Trial name
- Hololens (NCT04028284)
- Testing
- HoloLens-guided epidural, US-guided epidural
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetes, Schizophrenia
Pioglitazone as a Treatment for Lipid and Glucose Abnormalities In Patients With Schizophrenia
This is a study with an approved drug for treating type 2 diabetes, for its effects on treating glucose and lipid abnormalities in patients being treated with first or second-generation antipsychotics, and comparison of effects…
- Conditions
- Diabetes, Schizophrenia, Insulin Resistance, Cognitive Impairment
- Trial name
- NCT00231894
- Testing
- Pioglitazone, Life style diet group
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Memory Loss
Dietary Flavanols and Dentate Gyrus Function
to assess the effect of differing amounts of a cocoa-derived dietary flavanol (epicatechin ) on dentate gyrus function and corresponding cognitive function
- Trial name
- NCT02312310
- Testing
- Cocoa Flavanol
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Anxiety, Depression
Neuromodulation Enhanced Cognitive Restructuring: A Proof of Concept Study
Psychological treatments are effective, but take a long time and can be burdensome. Therefore, avenues to optimize behavioral treatments are needed.
- Conditions
- Anxiety, Depression, Personality Disorders, Trauma and Stress-related Disorders
- Trial name
- NCT02573246
- Testing
- Cognitive Restructuring, rTMS
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Duke University
Multiple Sclerosis, Neurological Disorder
Cognitive Remediation Augmented With Transcranial Direct Current Stimulation (tDCS)
The proposed study will test the feasibility and tolerability of transcranial direct current stimulation (tDCS) added to a cognitive remediation program in n=100 adults.
- Trial name
- NCT03049969
- Testing
- tDCS stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Fear of Flying
Targeting Reconsolidation to Prevent Return of Fear
The overall aim of this project is to determine if using a cue to trigger (and reactivate) the fear memory 10 minutes prior to exposure treatment sessions leads to less anxiety in patients with a fear of flying.
- Trial name
- NCT01623830
- Testing
- Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Emory University
Diabetes Mellitus, Type 1
A Study on the Effect of 2 Pen Devices on HbA1c
The purpose of this study is to test the hypothesis that the HumaPen Memoir with memory function, when used over 24 weeks for prandial insulin injections achieves superior glycemic control, when compared to the conventional…
- Trial name
- NCT00985712
- Testing
- Insulin Lispro, Huminsulin Regular, HumaPen Memoir
- Where
- 29 sites in Germany
- Volunteers
- 263 people
- Sponsor
- Eli Lilly and Company
Alzheimer's Disease
A Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Participants With Early Alzheimer's Disease
This study seeks to evaluate the efficacy and safety of ABBV-8E12 in participants with early Alzheimer's disease (AD).
- Trial name
- NCT02880956
- Testing
- ABBV-8E12
- Where
- 68 sites in United States, Australia and 9 more
- Volunteers
- 453 people
- Sponsor
- AbbVie
Kidney Transplant; Complications, Toxicity
Effect of Tacrolimus Formulation on Neurological Side Effects in Older Kidney Transplant Recipients
Previous studies have shown that elderly patients experience higher trough levels of tacrolimus and are more sensitive to the effects of medications, they experience higher occurrence and severity of such medication related…
- Conditions
- Kidney Transplant; Complications, Toxicity, Drug Toxicity, Neurotoxicity
- Trial name
- NCT03461445
- Testing
- Envarsus, IR Tacrolimus
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of California, Davis
Schizophrenia, Psychosis
Non-Invasive Direct Current Stimulation for Cognition in Schizophrenia
This study proposes to assess the effect of trans-cranial direct current stimulation (tDCS) on cognitive control, working memory, functional, clinical, and cognitive outcomes in schizophrenia patients.
- Trial name
- NCT02739347
- Testing
- Active Trans-cranial direct-current stimulation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Attention, Memory
Polyunsaturated Fatty Acids (PUFA) Status and Cognitive Function in Healthy Young Adults
To date, the relationship between omega-3 polyunsaturated fatty acids (n-3 PUFAs) in cognitively intact individuals has only been examined in a limited number of studies; it is at present unknown whether supplementation with n-3…
- Conditions
- Attention, Memory, Mood, Mental Fatigue
- Trial name
- NCT01075958
- Where
- United Kingdom
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Haemophilus Influenzae Type b, Neisseria Meningitidis
Dose Ranging Study of Combined Haemophilus Influenzae Type B-Meningococcal Serogroups CY (Hib-MenCY-TT) Vaccine
This study evaluated the safety and immunogenicity of 3 formulations of Hib-MenCY-TT vaccine compared to 2 control groups receiving licensed meningococcal serogroup C conjugate vaccine and/or licensed Hib conjugate vaccine…
- Trial name
- NCT00127855
- Testing
- Hib-MenCY-TT vaccine (MenHibrix), Meningitec®, ActHIB®
- Where
- 3 sites in Australia
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Traumatic Brain Injury
Memantine for Neuroprotection and Cognitive Enhancement Following Traumatic Brain Injury
The purpose of this study is to determine if memantine can improve cognitive and neuropsychiatric outcomes after severe traumatic brain injury.
- Trial name
- NCT02240589
- Testing
- Memantine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Indiana University
Schizophrenia
Neurocognitive Effects of Ziprasidone: Relationship to Working Memory and Dopamine Blockade
Ziprasidone is a newer drug intended for the treatment of the symptoms of schizophrenia. This new drug may have an added benefit of being able to help with some of the difficulties in problem solving and memory that many patients…
- Trial name
- NCT00225498
- Testing
- ziprasidone vs risperidone or olanzapine
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Northwell Health
Mild Cognitive Impairment
Water-based Activity to Enhance Recall in Veterans
This two-year study will evaluate the feasibility of an exercise training augmentation for cognitive training intervention to improve memory performance in Veterans with a diagnosis of amnestic Mild Cognitive Impairment (aMCI).
- Trial name
- WATER-VET (NCT02614092)
- Testing
- Water-based Activity + Cognitive Training
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Schizophrenia, Schizoaffective Disorder
Effect of Single Dose Intranasal Insulin On Cognitive Function
The purpose of the study is to find out how a small dose of insulin might affect memory, the ability to concentrate, and improve your daily functioning in patients with schizophrenia and schizoaffective disorders.
- Trial name
- NCT00646581
- Testing
- Insulin (Humulin)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Schizophrenia
Effects of Eszopiclone on Sleep and Memory in Schizophrenia
The investigators will test the hypothesis that the sleep medication, eszopiclone, can normalize brain activity during sleep and improve memory in patients with schizophrenia.
- Trial name
- NCT01641900
- Testing
- eszopiclone
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy Adults
Investigating Accelerated Learning in Healthy Subjects: Trigeminal Nerve Stimulation
The purpose of this study is to investigate whether it is possible to accelerate learning and improve associative memory performance in healthy subjects, by applying transcranial Direct Current Stimulation (tDCS) targeting the…
- Trial name
- NCT03138590
- Testing
- Transcranial Direct Current Stimulation- Neuroconn DC Stimulator PLUS
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Acceptability of an Exercise Intervention
Exercise Snacking to Improve Strength and STability: ESISST Pilot Study
As we age, muscles can become progressively weaker to the point that tasks of daily living cannot be carried out safely. However, regular resistance exercise training has been shown to maintain and even increase muscle strength…
- Trial name
- ESSIST (NCT05439252)
- Testing
- Exercise Snacking
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Bath
Cognitive Dysfunction
Feasibility of the Memory and Attention Adaptation-Training Geriatrics Intervention in Older Cancer Survivors With Mild Cognitive Impairment
Cancer-related cognitive dysfunction (CRCD) affects up to 75% of patients receiving chemotherapy and older adults are at greater risk of developing CRCD, which can negatively affect their functional independence and quality of…
- Trial name
- urochester (NCT05258058)
- Testing
- Memory and Adaptation Training-Geriatrics
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Allison Magnuson