Clinical trials: Men Who Have Sex With Men
HIV/AIDS
Access to PrEP for MSM: Acceptability and Feasibility in Community-based Clinics in West Africa (CohMSM-PrEP)
This demonstration project will assess the acceptability and feasibility of pre-exposure prophylaxis (PrEP) for men who have sex with men (MSM) as part of a comprehensive HIV prevention package in community-based clinics in West…
- Trial name
- CohMSM-PrEP (NCT03459157)
- Testing
- HIV prevention package including PrEP
- Where
- 4 sites in Burkina Faso, Côte d’Ivoire and 2 more
- Volunteers
- 649 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Anal Carcinoma, HIV Infection
Anal Cytology Collection Procedures in Predicting High-Grade Anal Dysplasia in Men Who Have Sex With Men
This clinical trial compares three anal cytology collection procedures (collected at a single visit) in men who have sex with men (MSM).
- Conditions
- Anal Carcinoma, HIV Infection, Human Papillomavirus Infection
- Trial name
- NCT02816879
- Testing
- Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
- Where
- 3 sites in United States
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Anal Cancer, Quality of Life
Prospective Cohort on Quality of Sexual Life Among Men Who Have Sex With Men Treated for Anal Cancer With Concurrent Chemotherapy and Intensity-modulated Radiotherapy
Treatment of anal cancer has been always linked to quality of life. Recently, with development on radiotherapy technique, toxicities have been lowered with the maintenance of adequate rates of disease control.
- Trial name
- NCT02949596
- Testing
- Quality of life and quality of sexual life questionnaires
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Anal High-grade Squamous Intraepithelial Lesion
Anal HSIL Screening Algorithm
This the propose to use the Multiphase Optimization Strategy Trial (MOST) design to identify an anal HSIL screening algorithm which is most suitable in terms of effectiveness, efficiency, and economy.
- Trial name
- 0007/65 (NCT05531799)
- Testing
- OPTIMIZATION PHASE
- Where
- Thailand
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
HIV, Sexually Transmitted Diseases
LYNX: A Novel Mobile App to Support Linkage to HIV/STI Testing PrEP for Young Men Who Have Sex With Men
This study is testing the acceptability and feasibility of a highly interactive mobile application (app) to promote HIV/sexually transmitted infection (STI) testing and uptake of pre-exposure prophylaxis (PrEP) among young men…
- Conditions
- HIV, Sexually Transmitted Diseases, Risk Reduction, Pre-Exposure Prophylaxis
- Trial name
- NCT03177512
- Testing
- LYNX Mobile App
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda.
Hazardous alcohol use, which is common among men in Uganda, is a primary driver of both HIV risk and intimate partner violence (IPV) in this setting.
- Trial name
- Kisoboka Amaka (NCT06900634)
- Testing
- Kisoboka Amaka, Screening and Referral
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- San Diego State University
HIV Infections
Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection Among Men and Transgender Persons Who Have Sex With Men
This study will evaluate the safety and efficacy of the human monoclonal antibody (mAb) VRC-HIVMAB060-00-AB (VRC01) in preventing HIV-1 infection among men and transgender (TG) persons who have sex with men, in North America…
- Trial name
- NCT02716675
- Testing
- VRC01
- Where
- 26 sites in United States, Brazil and 2 more
- Volunteers
- 2,699 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
PrEP Uptake
MI-based PrEP Intervention
Gay, bisexual and other men who have sex with men (MSM) are the group at highest risk of HIV infection in the United States. Pre-exposure prophylaxis (PrEP) has demonstrated high efficacy in preventing HIV infection among MSM.
- Trial name
- NCT03313765
- Testing
- Motivational interviewing (MI), Standard-of-care
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
HIV/AIDS, Mobile Health
Evaluation of a Multi-Component Intervention to Support HIV Testing and Linkage to Services Among MSM in Peru
This study is testing a new program designed to improve access to HIV testing and help connect people with available treatment or prevention services, based on their test result.
- Conditions
- HIV/AIDS, Mobile Health, Feasibility Studies, Qualitative Research
- Trial name
- MERCURY (NCT07074899)
- Testing
- Multi-component HIV testing and linkage-to-services intervention
- Where
- 2 sites in Peru
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Stimulant Abuse, HIV Prevention
Integrated BA and HIV RR Counseling for MSM With Stimulant Abuse
This study seeks primarily to test, in a two-arm randomized controlled trial (RCT), the efficacy of Project IMPACT, an intervention that integrates Behavioral Activation (BA) with HIV risk reduction (RR) counseling for…
- Conditions
- Stimulant Abuse, HIV Prevention, Substance Abuse
- Trial name
- NCT03175159
- Testing
- IMPACT, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV
Home Self-Testing for HIV to Increase HIV Testing Frequency in Men Who Have Sex With Men (The iTest Study)
The purpose of this study is to determine whether the availability of home self-testing for HIV will increase HIV testing frequency among men who have sex with men without negatively impacting their risk for HIV acquisition.
- Trial name
- NCT01161446
- Testing
- Home HIV self-testing with OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Washington
Anal Cancer
Assessing Drivers and Barriers to Follow-Up Screening for Anal Cancer in Men Who Have Sex With Men
This study is designed to identify barriers that prevent men who have sex with men from receiving doctor-recommended annual follow-up screenings for anal cancer.
- Trial name
- NCT00501306
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Laser Surgery Care
HIV
Youth mHealth Adherence Intervention for HIV+ YMSM
This study will help determine feasibility, acceptability, and preliminary efficacy of an app for HIV medication adherence over a 3-month period.
- Trial name
- NCT03092115
- Testing
- HIV medication adherence app
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Drug Dependence
Drug Use During Sex and Its Impact on Taking PrEP (Pre-Exposure Prophylaxis) : CONSUME
This is a cross-sectional, single-center observational study conducted from October 2020 to March 2021 in Ile de France at the infectious disease of CHU Bichat (PrEP and CeGIDD(Free Center for Information, Screening and Diagnosis…
- Trial name
- CONSUME (NCT04709016)
- Testing
- self-questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV
HPTN 073 Black Men Who Have Sex With Men (MSM) Pre-Exposure Prophylaxis (PrEP)
Black men who have sex with men (MSM) Pre-Exposure Prophylaxis (PrEP) Study with Client Centered Care Coordination (C4) Component.
- Trial name
- NCT01808352
- Testing
- Observational
- Where
- 3 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Syphilis
Syphilis Self-testing to Expand Test Uptake Among Men Who Have Sex With Men (SST)
Syphilis infection is a major global health problem, leading to substantial morbidity among key populations in low- and middle-income countries (LMICs).
- Trial name
- NCT04480749
- Testing
- Access to Facility based Syphilis Testing, Syphilis Self-Test
- Where
- Zimbabwe
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Suicide
Implementing Evidence Informed Practices in Schools to Address LGBTQ Adolescent Suicide
Reducing youth suicide in the U.S. is a national public health priority. Sexual and gender minority adolescents are at elevated risk for suicide. Safer school environments, however, can decrease this risk.
- Trial name
- RLAS (NCT02875535)
- Testing
- RLAS
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
HIV Infections
HIV Prevention Among Latina Transgender Women Who Have Sex With Men: Evaluation of a Locally Developed Intervention
Wake Forest University and its partners, Triad Health Project, and the University of North Carolina, Greensboro, will be evaluating the effectiveness of ChiCAS (Chicas Creando Acceso a la Salud or Girls Creating Access to…
- Trial name
- NCT03465852
- Testing
- ChiCAS
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Anal Cancer
The Prevent Anal Cancer Self-Swab Study
The purpose of this research study is to find ways to screen for anal cancer among gay, bisexual, and other men who have sex with men (MSM) and transgender persons.
- Trial name
- NCT03489707
- Testing
- Home-based human papillomavirus (HPV) DNA screening, Clinic-based human papillomavirus (HPV) DNA screening
- Where
- United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
HIV
Evaluating a Real-Time, Remote Monitoring System for Home-Based HIV Testing
This study explores whether offering follow-up counseling and referral over the phone after using a home-based HIV test increases rates of ever and repeat testing, compared with home-based testing with no follow-up (HBST alone)…
- Trial name
- (eTEST) (NCT02876926)
- Testing
- "Smart" home-based test for HIV, Home-based testing only, Reminder letters for clinic-based testing
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Brown University